Term
Formation of Red Blood Cells (Erythropoesis) Diagram |
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Definition
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Term
Formation of Red Blood Cells (Erythropoeisis) |
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Definition
1. Hemocytoblast (stem cell) 2. Proerythroblast (comitted cell) 3. Early erythroblast ( a nucleated cell in the bone marrow from which red blood cells develop) -Phase 1: cell prepares to synthesize hemoglobin by producing huge #'s of ribosomes (site of protein synthesis) 4. Late erthroblast -Phase 2: hemoglobin is synthesized and accumulates in cytoplasm of cell. 5. Normoblast -Phase 3: The erythoblast ejects its nucleus and most of its organelles. 6. Reticulocyte (Essentially a young RBC or erythrocyte- Still contains a small # of clumped ribosomes and rer- mature fully within 2 days as their ribosomes are degraded by intracellular enzymes). 7. Erythrocyte (Red Blood Cell) *An overabundance of erythrocytes or excessive oxygen in the bldstream depresses RBC production. *The # of erythorocytes in the bld does NOT control the rate of erythropoeisis- its their ability to transport enough oxygen and meet tissue demands.
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Term
White Blood Cells (Leukocytes) |
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Definition
*There are far less that RBC (App. 1% of total blood volume) *Have a nuecleus and organelles ( A differentiated structure within a cell, such as a mitochondrion, vacuole, or chloroplast, that performs a specific function.) *Do not contain hemoglobin ( the oxygen-carrying pigment of red blood cells that gives them their red color and serves to convey oxygen to the tissues) *Unlike RBCs, WBC's are not confined to the bloodstream, but are able to move through the loose connective tissue via amoebid motion *Involved in body protection (Inflammatory and immune response)
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Term
| 2 Major Groups of WBC (Leukocytes) |
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Definition
Granular Leukocytes (Granulocytes) Agranular Leukocytes (Agranulocytes)
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Term
Granular Leukocytes (Granulocytes)
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Definition
* Have lobed nuclei (Rounded nuclear masses connected by thinner strands of nuclear material. *Numerous granules in the cytoplasm- These granules differentially in hematological stains. *Give rise to three types -neutrophils -basophils -eosinophils (Functionally they are all phagocytes:A cell, such as a white blood cell, that engulfs and absorbs waste material, harmful microorganisms, or other foreign bodies in the bloodstream and tissues) [image][image] |
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Agranular Luekocytes (Agranulocytes) |
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Definition
*Lack visible cytoplasmic granules. *Nuclei are typically spherical or kidney shaped *Includes: -Lymphocytes -Monocytes (These resemble each other structurally but are functionally distinct and unrelated cell types) |
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Term
| Hematopoietic stem cells (HSC) are stem cells and the early precursor cells which give rise to: |
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Definition
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Hemostasis (Blood Standing Still) |
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Definition
The stoppage of bleeding
*If a blood vessel wall breaks, a whole set of reactions are set into progress. *The response is fast, localized and involves many blood coagulation factors that are normally present in the plasma or may be released from platelets and injured tissue cells. |
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Term
A Decrease in normal blood oxygen, which causes relese of EPO is due to: (EPO- Erythroprotein hormone. A small amount of this normally circulates in the blood. Whe |
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Definition
1. Reduced #'s of RBC's due to hemmorrahge or excess RBC destruction. 2. Reduced availability of of oxygen to the blood as might occur in high altitudes or during pneumonia. 3. Increased tissue demands for oxygen- common in those who engage in arerobic exercise. |
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