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Understanding Pathophysiology Chapter 23
Alterations of Cardiovascular Function
28
Nursing
Undergraduate 1
08/28/2013

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Term
Hypertension (HTN)
Definition
"Silent Killer" High blood pressure. Caused by increased and sustained vasoconstriction or increased blood volume (fluid overload). Increase in systolic pressure. Sustained 140/90 or greater.
Term
Varicose vein
Definition
Vein in which blood has pooled, producing distended, tortuous and palpable vessels.
Term
Blood pressure
Definition
Pressure that blood exerts against the arteries.
Term
Hypertension Statistics
Definition
1/3 of Americans have HTN. 2/3 of people older than 60 have HTN.
Term
Hypertension SxS
Definition
Headache, blurred vision, dizziness, nose bleeds, peripheral edema, increased heart rate, chronic weakness,
Term
Chronic Venous Insufficiency (CVI)
Definition
Inadequate venous return over a long period
Term
Target Organ Disease
Definition
HTN had heavy impact on kidneys (renal failure), brain (CVA), heart (Cadiomyopathy), Arteries (CAD)(PAD)
Term
Hypertension Types
Definition
Primary: 92-95%
Secondary: 5-8%
Term
Primary Hypertension Risk Factors
Definition
Mod: Smoking, alcohol, high Na+ intake, obesity, low intake of K+, Ca2+, Mg 2+, stress, sleep deprivation
Non-mod: Heredity, age, race, sex, diabetes
Term
Stress
Definition
Stimulates sympathetic nervous system. Emotional and Physical.
Term
Secondary Hypertension Risk Factors
Definition
Underlying disorders such as renal disease, adrenal tumors, oral contraceptives, corticosteroids, antihistamines, pre/eclampsia
Term
Thrombus
Definition
Blood clot that remains attached to a vessel wall
Term
Thromboembolus
Definition
Detached thrombus
Term
Deep Vein Thrombosis
Definition
Occurs in the lower extremities
Term
Triad of Virchow
Definition
Promotes venous thrombosis. 1.) Venous stasis 2.) Venous endothelial damage 3.) Hypercoagulable states
Term
Superior Vena Cava Syndrome
Definition
Progressive occlusion of the SVC that leads to venous distension in the upper extremities and the head
Term
Renin-Angiotensin-Aldosterone System (RAAS)
Definition
Regulates long term blood pressure and intravascular fluid
Term
Hypertension Drug Treatment
Definition
ABCD - ACE inhibitors, Beta-blockers, Calcium channel blockers, Diuretics
Term
ACE
Definition
Enzyme that causes vasoconstriction
Term
Beta-1
Definition
Beta-1 receptors in the heart tell the heart to pump harder and faster
Term
Calcium Channels
Definition
Calcium is a ion that helps the heart contract
Term
Diuretics
Definition
Offload fluid
Term
Primary Hypertension
Definition
Genetic: Defect in renal Na+ excretion, overactive sympathetic nervous system, disorder of the renin-angiotensin-aldosterone system (RAAS)
Environmental: Modifiable risk factors
Term
Stages of Primary Hypertension
Definition
Stage 1: BP is 140-159 systolic and 90-99 diastolic.
Stage 2: BP is >160 systolic and >100 diastolic
Term
Complicated Hypertension
Definition
Target Organ Damage
1.)Malignant HTN (Hypertensive Crisis)
Term
Malignant HTN (Hypertensive Crisis)
Definition
Diastolic pressure of >140 mm hg. Main danger is cerebral edema and coma. SxS - headache, confusion, unresponsiveness, diaphoresis, chest pain, red skin, anxiety, impending doom. Nitro will be given immediately.
Term
Orthostatic Hypotension (Standing)
Definition
Can be both acute and chronic. 20-10-20 Rule.
Chronic: secondary to a specific disease, or idiopathic
Term
20-10-20 Rule
Definition
Decrease in systolic pressure by 20
Decrease in diastolic pressure by 10
Increase in heart rate by 20
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