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UMB OTC-GI Part 1 and 2
P3 - Exam 2
102
Pharmacology
Professional
11/25/2016

Additional Pharmacology Flashcards

 


 

Cards

Term
4 Degrees of hemorrhoids
Definition
1rst - enlarged
2nd - fall out but auto return
3rd - fall out; manual return
4th - stuck out of the butt
Term
Goals of treating for anorectal disorders
Definition
1. soft stools
2. less straining
3. cure and prevent symptoms
Term
Non-pharm for anorectal
Definition
1. hydrate
2. 20-30g fiber per day
3. don't lift heavy
4. avoid: alcohol, caffeine, citrus and spice
5. < 120 deg Sitz bath QID for 20min
Term
Pharm treatments for anorectal
Definition
-Local anesthetics
-Vasoconstrictors
-Protectants
-Astringents
-Keratolytics
-Coticosteroids
-Analgesics/anesthetics/antipuritics
Term
Anorectal OTC exclusions
Definition
<12yo
Ulcerative colitis/crohns
FH of colon cancer
Dx-ed or potential serious disorders
Severe symptoms
Term
How long can we treat anorectal disorders OTC
Definition
7 days
Term
Medical referral req. anorectal disorders
Definition
pain
bleeding
seepage
change in BM pattern
Prolapse
Thrombosis
Term
2 problems with using local anesthetics?
Definition
Mask pain - hide serious problem
Can cause an allergic rx in distinguishable from anorectal symptoms
Term
T/F Use local anesthetic on open sores?
Definition
F
Term
Name some local anesthetics ending in "caine" used in anorectal Tx
Definition
Benzo
Bibu
Tetra
Term
Name some local anesthetics ending in "ine" used in anorectal Tx
Definition
dyclon
Pramox
Term
Name the remaining local anesthetics used in anorectal Tx
Definition
Benzyl alcohol
Term
List the 2 vasoconstrictors used in anorectal Tx
Definition
ephedrine
phenylphederine
Term
List 3 astringents used in anorectal Tx
Definition
calamine
Zinc oxide
Witch hazel
Term
Keratolyics used in anorectal Tx
Definition
Alcoxa
Resorcinol
Term
Analgesic/anesthetics/pruitics used in anorectal Tx
Definition
Menthol
Juniper
Camphor
Term
Astringents, protectants, keratolytics, and analgresics/anesthetics/antipruritics, and some local anesthetics are used how many times per day in anorectal tx?
Definition
6 times per day
Term
Vasoconstrictors. hydrocortisone and some local anesthetics are used how many times per day in anorectal tx?
Definition
4 times per day
Term
Which pts should avoid using vasoconstrictors to tx anorectal
Definition
DB
Heart disease
HTN
Antidepressants
Thyroid disease
Term
T/F Witch Hazel can be used internally?
Definition
F
Term
T/F Keratolytics (acloxa, resorcinol) can be used internally?
Definition
F
Term
T/F Hydrocortisone can mask symptoms of bacterial/fungal infection
Definition
T
Term
Onset of hydrocortisone is
Definition
12hr, but longer duration
Term
T/F Using too much or eating analgesics/anesthetics/antipruritics (aka: Camphor, Junipor tar [phenol], menthol) can cause death
Definition
T
Term
Active ingredient in all Perp H formulations
Definition
phenylephrine aka: vasoconstrictor
Term
Active ingredient in TUCKS fromulations with the exception of the protectant which uses witch hazel only is:
Definition
Praxamine
Term
Pregnant people and anorectal therapy
Definition
Any external products, and protectants int/ext which are all oily greasy and disgusting messes
Term
How to stick a drug in you butt
Definition
left side
fetal
insert
wait 15-20
Term
For the most part OTC tx of anorectal disorders is limited to
Definition
burning, itching, discomfort, swelling, and irritation
Term
Which anorectal protectant to use?
Definition
Always select the anorectal protectant tx with the fewest ingredients
Term
How to use ORS in vommiting
Definition
wait 10 min after spew
5mL/5min thereafter for peds
15mL/5min adults
Term
Which antihistamines are used off-label to treat motion sickness
Definition
Doxylamine (Once daily)
Dimenhydrinaete (Q6h)
Diphenhydramine (Q4h)
Term
What is the only FDA approved drug for treating vomiting?
Definition
Meclizine
Term
Use meclizine in children <12yo?
Definition
No
Term
Seek medical attention for vomiting if
Definition
dehydrated
more than 5 pcs doses
Term
PCS is
Definition
Phosphorated carbohydrate solution
Term
PCS is used to treat
Definition
Nausea due to over eating
Term
T/F H2RA (cimetidine, ranitidine, famotidine) are also approved to treat Nausea due to over eating
Definition
T
Term
What normally causes diarrhea
Definition
Rotavirus - kids
Norovirus - adults
Term
Where do adults catch the norovirus?
Definition
Restaurants, cruise ships, LTC facs...
Term
Rotavirus is seasonal?
Definition
True. November-February
Term
Four clinical classes of diarrhea
Definition
Osmotic - viruses, e coli...
Secretory - c diff
Inflammatory - UC, Chron's
Motor - IBS, DB neuropathy
Term
5 types of diarrhea
Definition
Viral
Bacterial
Food-borne
Traveler's
Food induced
Term
Causes of food induced diarrhea
Definition
fat, fiber, lactose
Term
Causes of travelers diarrhea
Definition
some form of e.coli
Term
Goals of therapy in diarrhea and vomitting
Definition
1. Correct fluid balance
2. Control symptoms
3. ID and treat cause
4. Reduce death and other morbidities
Term
Refer diarrhea pts to hospital after...
Definition
48hrs
Term
Treat diarrhea with loperamide
Definition
4mg initial 2 mg after 2 more lose stools. Max dose is 8mg/day
Term
Ways to treat diarrhea
Definition
Loperamide
Bismuth subsalicylate
Lactase
Term
Bismuth subsalicylate for kids <12?
Definition
NO!
Term
Bismuth subsalicylate products
Definition
kaopectate
Maalox
epto bismol
Term
Bismuth subsalicylate dosing
Definition
525 every 30-60min max 8 doses or 4200mg
Term
Mainstay of diarrhea therapy is
Definition
ORS - Only acute patients with moderate diarrhea are candidates for anything else
Term
Symptoms of constipation
Definition
fewer than 3 bm/week
Term
Constipation treatment goals
Definition
1. Relief
2. Diet/exercise
3. Safe use of Lax
Term
Seek medical care after
Definition
7days of OTC Tx
14 days of symptoms
Term
Exclusions for OTC treatment of constipation
Definition
Lots of farting
Lots of Ab pain
Signs of disease like ever, vomiting...
Blood...Dark tarrys...
Term
Examples of bulk forming laxatives
Definition
anything "fiber"
Citrucel
Metamucil
Term
Onset of actions for constipation meds
Definition
Peg 33550 12-72hr
Docusate 12-72hr
Bulk-forming 12-24hr
Senna/Bisacodyl 6-10hr
Saline Lax 0.5-6hr
Glycerin 15min
Term
Two hyperosmotic agent for constipation tx...and how they are dosed
Definition
PEG 3350 - 17g/day
Glycerin - 1 supp.
Term
Peg 3350 OTC for <17yo
Definition
NO
Term
List emollient agents related to the tx of constipation...and how they are dosed
Definition
Docusate - up to 300mg daily divide at will
Term
List saline lax agents
Definition
Magnesium or sodium anything...
Term
Worries with saline lax
Definition
electrolytes
Mg tox = hypotension, fatigue
Term
T/F Senna turns pee pink?
Definition
T
Term
Stimulant agents for the tx of constipation
Definition
senna 34.4mg/day max (8.6/17.2 tabs)
bisacodyl 1-3 5mg tabs per day - or supp.
Term
Patients should separate oral meds from bulk-forming lax by how many hours?
Definition
2hrs - b/c of absorption effects
Term
T/F DB pts should use bulk-forming lax with caution bc of sugar content?
Definition
T
Term
T/F Docusate and mineral oil can be used together
Definition
NOOOOOOO - causes absorption
Term
Major problem with mineral oil is
Definition
everything, but more specifically lipid pneumonia b/c of aspiration
Term
Problems with saline lax
Definition
1. Bad for electrolyte balance
2. Drug to drug interactions
3. Not for Renal pts
4. Not for heart pts
Term
T/F Senna turns your anus brown
Definition
t
Term
Senna has a bunch of complication like
Definition
1. absorption probs
2. protein loss
3. dehydration
4. CRAMPING
Term
I took a bisacodyl enteric coated tab; how long before I can take the rest of my druggie drug drugs?
Definition
1hr
Term
Pregnancy constipation choices
Definition
Bulk-forming / Diet
Term
t/F Phenylketouria pts cannot use sugar-free-bulf-forming lx
Definition
T
Term
OTC + PEG 3350 + IBS =
Definition
NO
Term
Antacids such as Tums, Mylanta, Rolaids, and Alka-Seltzer can relieve heart burn in as little as ____ minutes
Definition
5
Term
Primary ingredients of antacids
Definition
Sodium bicarb - Alka-Seltzer
Aluminum + Mg /hydro - Mylanta
Bismuth Subsal - Pepto
Calcium carb - Tums/rolaids
Term
Heartburn meds onset of action
Definition
Antacids = 5min
H2RA =30min
PPI = 2-3hr
Term
Short term relief of heartburn is provided by
Definition
antacids 5-30min
Term
H2RA duration of action is
Definition
4-10hr
Term
PPI duration of action is
Definition
21-24hr
Term
List approved H2RAs for OTC heartburn relief
Definition
Tagamet = Cimetidine
Pepcid = famotidine
Zantac = ranitidine
Term
H2RA combos available for OTC are
Definition
Tums dual action + Pepcid complete = Famotidine/Ca carb/Mg hydrox
Term
Available OTC PPI and dosing
Definition
Prilosec (Omeprazole 20.6)
Term
How to take PPIs
Definition
30min before morning meal with glass of water
Term
Max length of OTC heartburn treatment
Definition
14days; one time within in 4 months
Term
T/F cimetidine can cause men to grow boobs, decrease libido, and impotence
Definition
T - weak anti-androgenic effect
Term
PPI Drug-to-drug interactions
Definition
MTX
Clopridigrel
Warfarin
Digoxin
Term
T/F PPI users have a higher risk of c. diff
Definition
TRUE
Term
Pregnancy, breast feeding, and Heartburn
Definition
Everything is safe pretty much:
- Antacids stick with Mg or Ca (Rolaids/Tums)
- No data on PPI and breast-feeding
Term
Heartburn and dyspepsia symptoms
Definition
post-prandial burning in central to upper abdomen
Term
Use a PPI when
Definition
2 or more episodes of heartburn per week
Term
Seek medical attention for heart burn if:
Definition
Severe symptoms arise
nocturnal episodes
Have for 3 months or more
Term
Exclusions for self treatment in the exciting world of internal gas
Definition
-If occurring more than 3tims per month for 3 months
-BM change
-Severe AB discomfort
Term
Which product(s)can be used after gas has formed?
Definition
simethicone Aka: gas-ex, Mylanta-gas
Term
Which internal gas products are taken at the start of meals
Definition
Alpha galactosidase
Probiotics
Term
You can cook with alpha galactsidase?
Definition
No - inactivates at 130deg
Term
Available products for the treatment of internal gas
Definition
Simethicone = Gas-Ex
Charcoal
Alpha Glacatosidase = Beano
Lactose=lactaid
Probiotics =lactobacillus = yogurt
Term
IBS vs. internal gas in location of pain
Definition
IBS is only in the lower abdomen, Int gas is everywhere
Term
IBS vs. Int gas in signs and symptoms
Definition
Int gas = belching farting

IBS = pain the ends after pooping...accompanied with diarrhea or constipation.
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