Term
In 4th to 5th week of life, a 4mm, human embryo develops a bud from the foregut that grows _________ and the cranial portion becomes the ________ and ________ _______ ________ |
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Definition
cephalad / liver and hepatic bile ducts |
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Term
In the caudal portion of the growing bud, there develops a second bud, or diverticulum, and this is destinated to become the _____ _______ and _________ ________ |
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Definition
gall bladder and cystic duct |
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Term
_________ _________ is a rare condition that results from the failure of the cystic bud to develop in the 4th week of intrauterine life |
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Definition
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Term
What is the treatment for a person with isolated agenesis of gallbladder? |
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Definition
The person with isolated agensis of the gallbladder is healthy. No treatment is needed. The prognosis is excellent |
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Term
What is the main function of the gallbladder? |
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Definition
The gallbladder's main function is to store bile |
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Term
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Definition
Bile is a bitter dark yellow/green digestive liquid produced by the liver |
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Term
What happens to the bile when stored in the gallbladder? |
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Definition
When stored in the gallbladder, bile becomes more concentrated and therefore more powerful in its ability to do its work |
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Term
Why does the gallbladder stores the bile? |
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Definition
to have it available in larger quantities for secretion when a meal is eaten |
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Term
Which hormone is released when food is ingested especially fats? |
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Definition
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Term
What does the hormone cholecystokinin do? |
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Definition
cholecystokinin turn signals the relaxation of the valve at the end of the common bile duct (the sphincter of Oddi) which lets the bile enter the small intestine |
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Term
What else does the CCK do? |
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Definition
It also signals the contraction of the gallbladder which squirts the concentrated liquid bile into the small intestine where it helps with the emulsification or breakdown of fats in the meal |
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Term
What is the muscular valve that controls the flow of digestive juices (bile and pancreatic juice)? |
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Definition
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Term
Through where does the digestive juice flow and where does it enter? |
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Definition
flows through the ampulla of vater and inters into the second part of the duodenum |
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Term
What does the CCK do to the Sphincter of Oddi? |
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Definition
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Term
What does bile consist of? |
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Definition
cholesterol, lecithin, calcium, bile salts, acids and waste materials among other things |
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Term
What happens when bile salts and cholesterol get out of balance with each other? |
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Definition
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Term
what does the liver continuously make and secrete into the bile ducts in varying amount? and where does it go? |
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Definition
bile
and some of it goes directly into the small intesting and some into the gallbladder |
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Term
What does the GB act when there is excess bile? |
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Definition
GB acts as a reservoir that uptakes excess bile when there is pressure in the bile ducts |
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Term
What is the function of bile? |
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Definition
it breaks down the fats that you eat so that your body can utilize them
bile is a very powerful antioxidant which helps to remove toxins from the liver |
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Term
Where does the GB lie and what shape does it have? |
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Definition
GB is a pear shaped organ lying in the inferior margin of the liver, between the right and left lobes |
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Term
What else lie in the same plane of the GB that can be used to help find the GB fossa? |
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Definition
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Term
What is the origin of the RPV to the GB fossa? |
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Definition
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Term
what is the landmark for the GB fossa? |
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Definition
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Term
From where does the GB derives its blood supply from? and where does it arise from? |
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Definition
the cystic artery which arises from the right hepatic artery |
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Term
Where does the cystic vein drain into? |
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Definition
directly into the portal vein |
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Term
What are the parts of GB? |
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Definition
Neck (which terminates in the narrow infundibulum)
Body
Fundus |
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Term
What is the angulated portion of the neck region called? what happens to that region? |
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Definition
infundibulum or hartmann's pouch
common location for impaction of gallstones |
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Term
Why is there failure to identify the GB on an ultrasound exam? |
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Definition
due to a previous cholecystectomy |
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Term
What leads to a collapsed and fibrosed GB making it difficult to detect? |
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Definition
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Term
What can be an other reson for the GB to be difficult to locate? |
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Definition
it may lie in an ectopic position |
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Term
What is it called when the GB fundus fold onto the body? |
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Definition
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Term
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Definition
composed of 2 or more intercommunicating compartments divided by thin septa |
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Term
What is the hourglass GB? |
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Definition
has thick septa seperating the components |
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Term
The intrahepatic bile ducts converge to form the - |
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Definition
right and left hepatic ducts |
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Term
the right and left hepatic duct join to form the - |
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Definition
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Term
The GB neck tapers to form the ___________ which joins with the _______ to form the ___________ |
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Definition
cystic duct - CHD - common bile duct |
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Term
the common bile duct and main pancreatic duct join to form the |
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Definition
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Term
main pancreatic duct is also known as |
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Definition
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Term
what is the small mucosal folds that forms within the cystic duct and sometimes in the GB neck? |
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Definition
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Term
what does the spiral valves of heister control? |
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Definition
bile flow in the cystic duct |
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Term
How does the GB appear sonographically? |
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Definition
sonolucent oblong structure |
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Term
Where does the GB lie to the right kidney |
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Definition
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Term
where does the gb lie to the head of pancreas and duodenum |
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Definition
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Term
what does the GB indent to? |
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Definition
the inferior to medial aspect of the right lobe of the liver |
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Term
What is the size of the GB? |
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Definition
less than 4 cm transverse
less than 10 cm sagittal |
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Term
What is the wall thickness of the GB? |
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Definition
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Term
How does the lumen look sonographically? |
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Definition
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Term
what is the location of the GB? |
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Definition
RUQ - between RT & LT lobes of the liver |
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Term
What within the liver connects the GB and the RPV or MPV? |
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Definition
bright linear reflector - main lobar fissure |
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Term
When is a prominent GB be normal? |
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Definition
in some individuals because of their fasting state |
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Term
If the GB appears too large what can be done? |
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Definition
administration of a fatty meal and further evaluation may differentiate between normal and abnormal |
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Term
if no contraction of the GB occurs what must be evaluated? |
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Definition
the pancreatic area for suspicious masses must be evaluated |
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Term
when must the exam of a GB be performed? |
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Definition
after a minimum of 6 hours fasting |
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Term
How does a well contracted GB change? |
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Definition
a strongly reflective outer contour
a poorly reflective inner contour
a sonolucent area between both reflecting structures |
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Term
How must the GB be evaluated? |
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Definition
evaluation of the GB is usually easily performed with routine sagittal and transverse ultrasounds but must be imaged in at least 2 patient position |
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Term
what must be done if the gb is not visualized? |
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Definition
maneuvers to evaluate the gb fossa are essential to avoid missing gb pathology |
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Term
Within the liver parenchyma the bile duct follow the same course as the - |
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Definition
portal veins and hepatic artery branches |
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Term
The common hepatic duct, portal vein and hepatic artery are encased in a common collagenous sheath that forms the ____________ |
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Definition
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Term
the proximal portion of the CBD is ________ to the proper hepatic artery and __________ to the main portal vein |
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Definition
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Term
The CBD becomes more posterior after it descends behind the - |
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Definition
duodenal bulb and enters the pancreas |
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Term
The distal CBD lies ________ to the anterior wall of the IVC |
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Definition
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Term
What are the common risk factors for GB stone (5 F's)? |
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Definition
Forty something
Female
Fat
Fertile
Fair Skinned
(Fair Female who are 40 years and fat are fertile) |
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Term
What are the symptoms of GB stones? |
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Definition
most patients are asymptomatic but some may show biliary colic (recurrent episodes of abd pain) |
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Term
What is highly sensitive in the detection of stones within the GB? |
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Definition
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Term
What results in an echogenic appearance with strong posterior acoustic shadowing in a GB? |
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Definition
the large difference in the acoustic impedance of stones and adjacent bile makes them highly reflective |
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Term
What is the key feature for looking for gb stones? |
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Definition
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Term
what differencitates the polyps or other entities in gb? |
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Definition
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Term
In case of gall stones how is it visualized? |
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Definition
the gb wall is first visualized in the near field followed by the bright echo of the stone, followed by the acoustic shadowing |
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Term
what is the acoustic shadowing of the gall stones called? what is it AKA? |
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Definition
WES (Wall Echo Shadowing)
AKA double arc |
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Term
What is the presence of a gallstone in the common bile duct? |
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Definition
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Term
What is the rare condition in which the gb becomes filled with a pasty semi solid substance made mostly of calcium carbonate? |
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Definition
milk of calcium bile
AKA limey bile |
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Term
how does milk of calcium bile in the gb appear sonographically? |
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Definition
highly echogenic material with posterior acoustic shadowing |
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Term
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Definition
biliary sludge, biliary sand or microlithiasis |
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Term
What is gallbladder sludge made up of? |
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Definition
residual particles that remain in the gb after it sends bile from the liver to the intestines to further break down food. |
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Term
What happens if the gb doesn't empty correctly? |
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Definition
protiens can be left behind, resulting in sludge in the gb. gb sludge can solidify forming gallstones |
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Term
what are the predisposing factors for gb sludge? |
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Definition
pregnancy
rapid weight loss
prolonged fasting
critical illness
bone marrow transplantation
biliary stasis
cystic duct obstruction
cholecystitis |
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Term
What are the complications for gb sludge? |
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Definition
stone formation
biliary colic
acalculous cholecystitis
pancreatitis |
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Term
How does gb sludge look sonographically? |
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Definition
amorphous, low level echoes within the gb in the dependent position with no shadowing |
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Term
what happens to the gb sludge with a change in position? |
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Definition
sludge may slowly resettle in the most dependent location |
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Term
When sludge mimicpolypoid tumors what is the sludge then called? |
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Definition
tumefactive sludge or sludge balls |
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Term
What is hepatization of the gb? |
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Definition
occasionally sludge has the same echotexture as the liver leading to camouflage of the gb |
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Term
what is caused by gallstones in more than 90% of the cases? |
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Definition
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Term
What happens when there is impaction of the stones in the cystic duct or the gb neck? |
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Definition
it results in obstruction with luminal distention, ischemia, superinfection and eventually, necrosis of the gb |
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Term
what is acute cholecystitis associated with? |
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Definition
RUQ pain, fever and leukocytosis (elev. wbc's) |
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Term
What is the complications of acute cholecystitis? |
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Definition
empyema
gangrenous cholecystitis
gb perforation
pericholecystic abscess |
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Term
What are the sonographic finding of acute cholecystitis? |
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Definition
thickened gb wall (>3mm)
distention of the gb lumen (>4cm)
gallstones
impacted stone in cystic duct or gb neck
pericholecystic fluid collecions
positive murphy's sign
hyperemic gb wall with doppler |
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Term
what lab value suggests obstruction at the level of the ampulla of vater? |
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Definition
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Term
What is the complications of acute cholecystitis? |
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Definition
gangrenous cholecystitis
emphysematous cholecystitis
empyema
gb perforation
acalculous cholecystitis
torsion (volvulus) of the gb
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Term
what is the finding for gangrenous cholecystitis? |
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Definition
loss of tissue due to decreased blood supply there are no specific ultrasound findings to define this |
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Term
What are the signs for gangrenous cholecystitis? |
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Definition
asymmetric wall thickening
wall striations
intraluminal membranes
pericholecystic fluid
the gb wall is necrosing |
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Term
Emphysematous cholecystitis of the gb due to - |
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Definition
gb wall ischemia and infection |
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Term
what ultrasound findings of emphysematous cholecystitis? |
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Definition
comet tail (reverberation) artifacts are seen due to the presence of gas within the wall/lumen of the gb due to gas forming bacteria
occurs more commonly in diabetic men |
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Term
What is the purulent material within the GB due to bacteria-containing bile associated with acute cholecystitis |
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Definition
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Term
Empyema is initiated with obstruction of the _________ |
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Definition
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Term
Where does GB perforation occur? |
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Definition
localized fluid collection in the GB fossa |
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Term
What does the complications include for GB perforation? |
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Definition
peritonitis
pericholecystic abscess
biliary fistula |
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Term
Which acute cholecystitis is without the presence of gallstones |
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Definition
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Term
Acalculous cholecystitis exists with conditions like |
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Definition
prolonged use of TPN
abd surgery
trauma
severe burns
sepsis
AIDS |
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Term
What is the rare acute cholecystitis but patients present with symptoms of acute cholecystitis? |
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Definition
Torsion (Volvulus) of the GB |
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Term
How does Torsion of the gb look like? |
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Definition
massively distended and inflamed gb lying in an unusual horizontal postion |
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Term
What happens if torsion is >180 degrees? |
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Definition
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Term
Recurring symptoms of biliary colic due to multiple previous episodes of acute cholecystitis is called - |
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Definition
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Term
How does chronic cholecystitis look sonographically? |
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Definition
doesn't appear different from acute cholecystitis |
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Term
What does chronic cholecystitis finding include? |
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Definition
thick-walled fibrotic contracted gb. sludge and an obsructing cystic duct stone may be present |
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Term
what is an unusual variant of chronic cholecystitis? |
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Definition
xanthogranulomatous cholecystitis |
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Term
How does xanthogranulomatous cholecystitis look like? |
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Definition
the gb is thickened and irregular with extension of yellow xanthogranulomatous inflammation to adjacent organs |
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Term
When is the gb wall thickned? |
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Definition
when it is greater than 3mm |
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Term
what is the common cause of gb wall thickness? |
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Definition
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Term
what are the causes for gb wall thickening? |
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Definition
hypoalbuminemia
ascites
hepatitis
chf
pancreatitis |
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Term
what happens when the gb is removed? |
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Definition
when the gb is removed bile is no longer retained in the bile ducts but is free to flow into the duodenum during fasting and digestive phases |
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Term
what happens to the extrahepatic bile duct after the gb is removed? |
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Definition
dilation of the extrahepatic bile duct, which is usually less than 1cm, occurs after gb removal |
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