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UC Med 2015
Glycolysis Steps
9
Medical
Professional
10/20/2011

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Term
First Step
Definition
Glucose is phosphorylated by hexokinase in cell cytoplasm. Uses 1 ATP so is irreversible
Term
Second Step
Definition
G-6-P is convervted to its isomer via phosphoglucose isomerase
Term
Third Step
Definition
F-6-P is phosphorylated on 1-carbon via phosphofructokinase. Uses 1 ATP so is irreversible
Term
Fourth Step
Definition
F-1,6-BP is acted upon via aldolase and triose phosphate isomerase that splits molecule in two.
Term
Fifth Step
Definition
Glyceraldehyde-3-phosphate is dehydrated via glyceraldehyde-3-phosphate dehydrogenase. Produces 1 NADH in this step
Term
Sixth Step
Definition
1,3 BPG is phosphorylated via phosphoglycerate kinase. Produces one ATP
Term
Seventh Step
Definition
3-phosphoglycerate's phosphate is relocated to second varbon via phosphoglycerate mutase.
Term
Ninth Step
Definition
2-phosphoenolpyruvate is phosphorylated via pyruvate kinase. Uses 1 ATP - IRREVERSIBLE STEP
Term
Eighth Step
Definition
2-phosphoglycerate is enolated via enolase
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