Term
| The following bacteria belong to what class: strep pneumoniae, s. pyogenes, s. aureus, enterococcus? |
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Definition
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Term
| The following bacteria belong to what class: clostridium spp., listeria, bacillus anthracis? |
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Definition
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Term
| What is the smallest free living organism? What is unusual about its cell wall? What is it's incubation period? |
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Definition
Mycoplasma pneumonia.
smallest free living organism, no cell wall.
incubation period of 3 weeks |
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Term
| What is an *intracellular* g- parasite? |
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Definition
| chlamydophila pnemoniae, related to chlamydia |
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Term
| What lives in an aquatic reservoir and is g- but hard to visualize or grow on a medium? |
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Definition
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Term
| What are 3 atypical bacteria? |
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Definition
| mycoplasma pneumoniae, chlamydophyla pneumoniae, legionella pneumophila |
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Term
| Depending on bacterial spp, by what amount can MIC vary? |
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Definition
| Minimum Inhibitory Concentration (MIC) of antibiotic can vary *100-fold* depending on bacterial species. Higher the MIC, more likely the bacteria will be resistant. |
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Term
| What abx has mic: e.coli(8)>staph aureus(1)>s.pyogenes(.1), and involves a resistance breakpt>8mg/L? |
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Definition
| 1st gen cephalosporin: Cefazolin (MIC in mg/L): |
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Term
| What abx has mic: enterobacter (16)>e.coli(.5)>s.pneumoniae(.05) and involves a resistance breakpt>8mg/L? |
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Definition
| 3rd gen cephalosporin: Ceftriaxone |
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Term
| What abx has mic: s.pneumoniae(2)>p.aeruginosa(.5)>enterobacter(.1) and involves a resistance breakpt > 1 mg/L? |
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Definition
| Fluoroquinolone: Ciprofloxacin |
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Term
| What type of therapy requires no gstain or culture to guide therapy; involves taking best guess at cause of infection; choice of abx depends on infection, most likely organisms, resistance patterns, severity, location, and immune status; involves a tendency to use more broad spectrum agents and a greater chance of failure and adverse effects? |
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Definition
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Term
| What type of tx is based on IDing organism by gstain or culture? |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
| signa/signetur-label/write/let it be labeled=directions for use |
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Term
| What is the moa of the following abx: penicillins? |
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Definition
| Inhibit bacterial cell wall synthesis |
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Term
| What is the moa of the following abx: cephalosporins? |
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Definition
| inhibit bacterial cell wall synthesis |
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Term
| What is the moa of the following abx: monobactams? |
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Definition
| inhibit bacterial cell wall synthesis |
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Term
| What is the moa of the following abx: monobactams? |
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Definition
| inhibit bacterial cell wall synthesis |
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Term
| What is the moa of the following abx: carbapenems? |
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Definition
| inhibit bacterial cell wall synthesis |
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Term
| What is the moa of the following abx: bacitracin? |
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Definition
| inhibit bacterial cell wall synthesis |
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Term
| What is the moa of the following abx: vancomycin? |
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Definition
| inhibit bacterial cell wall synthesis |
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Term
| What is the moa of the following abx: daptomycin? |
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Definition
| inhibit cytoplasmic membrane synthesis |
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Term
| What is the moa of the following abx: fluoroquinolones? |
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Definition
| inhibit bacterial dna gyrase |
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Term
| What is the moa of the following abx: macrolides and ketolides? |
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Definition
| inhibit bacterial protein synthesis |
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Term
| What is the moa of the following abx: tetracyclines? |
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Definition
| inhibit bacterial protein synthesis |
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Term
| What is the moa of the following abx: aminoglycosides? |
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Definition
| inhibit bacterial protein synthesis |
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Term
| What is the moa of the following abx: clindamycin? |
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Definition
| inhibit bacterial protein synthesis |
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Term
| What is the moa of the following abx: quinupristin-dalfopristin? |
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Definition
| inhibit bacterial protein synthesis |
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Term
| What is the moa of the following abx: mupirocin? |
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Definition
| inhibit bacterial protein synthesis |
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Term
| What is the moa of the following abx: linezolid? |
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Definition
| inhibit bacterial protein synthesis |
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Term
| What is the moa of the following abx: tmp-smx? |
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Definition
| inhibit bacterial folic acid synthesis |
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Term
| What gene codes for new pbp2a? |
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Definition
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Term
| To which B-lactam Abx is mrsa resistant? |
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Definition
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Term
| What percent of s.aureus were mrsa in 2008 in sentara hospitals? |
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Definition
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Term
| What percent of s.aureus were mrsa in 2008 in chkd hospitals? |
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Definition
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Term
| What is the drug of choice for mrsa? |
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Definition
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Term
| To what is ca-mrsa sensitive? |
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Definition
| clindamycin, doxycycline, bactrim |
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Term
| What is the most common infection in children tx w/abx? |
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Definition
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Term
| What is recommendation 3a for children w/uncomplicated acute otitis media? |
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Definition
| *observation* w/o use of abx in child w/uncomplicated aom is an option for selected children based on diagnostic certainty, age, illness severity, and assurance of follow-up |
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Term
| What is recommendation 3b for children w/ acute otitis media? |
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Definition
| if decision is made to tx w/abx, clinician should rx *amoxicillin* for most children, dose *80-90 mg/kg/day* |
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Term
| Describe the course of acute rhinosinusitis in most cases. (principle 4) |
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Definition
| *Acute rhinosinusitis resolves without antibiotic treatment in most cases [A]* |
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Term
| When are *abx recommended* in tx sinusitis in children? |
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Definition
| *abx are recommended* for the management of acute bacterial sinusitis to achieve a more rapid clinical cure |
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