Term
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Definition
A chronic, recurrent, infectious disease caused by Myobacterium Tuberculosis |
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Term
Who is at risk for contracting tuberculosis? |
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Definition
Pte with alcohol addition, immunosuppressed pts, HIV/AIDS pts, immigrants, pts that live in crowded spaces (homeless shelters, prisons), pts without health care access, health care workers, drug abusers |
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Term
How is tuberculosis transmitted? |
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Definition
Airborne droplet transmission |
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Term
How long does it take for cell-mediated immunity to develop against TB? |
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Definition
2 - 10 weeks after infx and manifested by + reaction to PPD test. |
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Term
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Definition
Inactive TB but has been exposed. Goes from a -- PPD to + PPD after exposure. |
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Term
What type of masks must health care workers use with TB pts? |
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Definition
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Term
If immune system is strong, what happens to the bacteria in the lungs? |
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Definition
Phagocytes engulf the bacteria, preventing the spread of disease into the lungs. Scar tissue can encapsulate bacilli and does not develop into disease. Lesions will calcify. These are visible on chest x-ray. |
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Term
If immune system is compromised, what happens to bacteria? |
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Definition
The tubercle bacilli can spread from lungs to other organs forming tubercles. If tubercle ruptures, bacilli spreads. |
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Term
Risk for transmission of TB is __________ after infxd pt received proper drug therapy for ________ weeks and acid-fast bacilli in ___________ culture reduced. |
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Definition
Reduced; 2 to 3 weeks; sputum |
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Term
What is Miliary or Hematogenous TB? |
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Definition
The spread of TB throughout the body when a large number of organisms enter the blood. |
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Term
Where can TB spread to in the body? |
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Definition
Kidneys, brain, spinal cord, bones/joints, liver/spleen |
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Term
What are signs/symptoms of TB? |
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Definition
Pts start out with fatigue and low-grade fever. Onset is gradual of all symptoms.
Low-grade fever, dry cough (nonproductive, purulent with hemoptysis), night sweats, chills, fatigue, weight loss, enlarged painful lymph nodes, anorexia/malnutrition, SHoB |
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Term
What are signs/symptoms in children? |
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Definition
Slight cough, HA, fatigue. Bacteria goes to the brain in kids and they can develop meningitis. |
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Term
What vaccine is used in high risk countries to prevent TB? |
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Definition
BCG vaccine used in high risk countries for high risk pts. It has live activated bacilli in serum. Pt will test + for TB for rest of life. |
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Term
What is the most reliable screening test for TB? |
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Definition
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Term
If skin test is +, what other tests are used to determine DX of TB? |
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Definition
Chest x-ray and positive sputum smear |
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Term
How is TB skin test administered? |
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Definition
Intradermal in forearm. Bevel up at 10-15% angle. Small amt of PPD is injected (0.1ml), |
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