Term
Tuberculosis is 200x more common in what demographic? |
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Definition
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Term
What diameter induration should be considered positive in HIV, high risk patients? Everyone else? |
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Definition
HIV-5mm High Risk - 10mm Everyone else - 15mm |
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Term
What tests are used to diagnosis TB? |
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Definition
Nucleic Acid Amplification (NAA) and cultures |
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Term
How do 90% of Primary infections manifest? |
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Definition
asymptomatic w/normal CXR |
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Term
What is the most common symptomatic presentation of pulmonary TB? |
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Definition
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Term
Extrapulmonary TB is most common in whom? |
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Definition
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Term
What is the most common clinical form of TB? |
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Definition
Reactivation (post-primary) TB |
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Term
What is the most rapidly progressive form of TB? |
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Definition
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Term
What is the most common extra-thoracic form of TB? |
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Definition
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Term
all HIV patients with an induration of 5mm or more should receive what drug and for how long? |
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Definition
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Term
Prophylaxis in HIV-negative patients 1) Recent converter 2) less risk factors 3) no risk factors |
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Definition
1) >5mm - INH 2) < 35yo and >10mm - treat, >35yo and >15mm - treat. 3) <35 yo and >15mm - INH |
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Term
What tests must be done before Anti-TB chemotherapy is given? |
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Definition
cultures and sensitivities |
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Term
When can you discharge someone from the hospital who was admitted for TB? |
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Definition
after 3 consecutive negative sputum cultures and clinical improvement |
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Term
According to the lecturer what are the 4 TB meds used? |
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Definition
1) Isoniazid (INH) 2) Rifampin 3) Pyrazinamide 4) Ethambutol or Streptomycin |
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Term
What is a major toxicity of Isoniazid? |
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Definition
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Term
What is a major side effect of Rifampin? |
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Definition
orange discoloration of urine, sweat, tears and saliva |
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Term
What is the most common opportunistic bacterial infection in AIDS patients? |
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Definition
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Term
Treatment plan for mycobacterium avium? |
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Definition
Antiretroviral therapy-control AIDS-may control infection.
Azithromycin/Clarithromycin |
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Term
What is characteristic of Leprosy and what causes it? |
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Definition
mutilation caused by sensory loss |
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