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what percent of the world infected with tb? |
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thought to be a romantic condition of the body/soul tragic but fashinable
eventually truth leads to sanitorium movement |
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bump in hte 802 90s in tb |
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who is really susceptible? |
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hiv close congregate housing |
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who is really susceptible? |
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hiv close congregate housing |
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Definition
7 percent multi drug 1 percent |
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mycolic acid lipid bilayer on inisde and outside cell wall makes it |
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80-90 percent no symptoms mild cold insidous onset untreated usually rspolves in 4-6 weeks small percent get progressive primary tb |
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neutrophilic phase subsequent mononuclear granulatomousinflammation caseous necrosis ghon complex |
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Vitamin __is important int he battle |
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primary tuberculosis indicator |
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tuberculosis commonly causes a __ disease |
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big hilar nodes, peripheral infiltrates ghon only in the ___ infection |
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macrohpages- active tb granuloma indicator. find the organism |
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because of ____ they are stained with AFB |
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in ht e small percent of patients with primary infectious tb they can spread it |
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MASSIVE hematogeous dissemination severelyill
usually primary though can occur in secodary fulminant illness heaptospleomegaly meningitis large caseuous nerotic break into the blood system through big vessel kills a lot |
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positive ppd, cxr with "old tb", inability to culture |
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two copeting hteories on latency |
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Definition
one that walled off granulomas lower ph and power o2 and replication is checked
2) organism spreads colonizes, protective immune response helps. |
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most important thing i am gonna say this his how you ttreat latent not active |
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Definition
12 months of inh .36 6 months of inh .5 2 months of inh and ripamfin |
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reactivation greates in the first___ years |
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lifetime risk of reactivation on Average |
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where would you see infiltrate on a secondary tb |
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apices of lung fluffy and cavy |
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where will you get extrapulmonary tb |
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larynx, pleura gi terminul ileum looks like corhns lymph meninges |
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peripheral lymph nodes tb |
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paravertebral nodes/vertebral bone tuberculosis |
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secondary tb in hiv infection |
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only 30 percent cavitate not at the apices |
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multi multi drugs! never give one for active 18-24 months inh, strep, PAS 9 months of inh and rif 6 months inh, rif and pyr |
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