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TSM 59
Cerebellum
23
Medical
Undergraduate 2
12/30/2012

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Cards

Term
Describe the function of the cerebellum?
Definition
1) It corrects the output of major DMP. It acts as a comparator between the cortical signal and resultant movement.
2) It is important in motor learning (interactions between climbing and mossy fibres).
Term
What are the deep cerebellar nuclei?
Definition
1) Fastigial
2) Interposed
3) Dentate
Term
What are the deep nuclei?
Definition
The deep cerebellar nuclei and the vestibular nuclei.
Term
Where is cerebellar input from?
Definition
The periphery and all levels of the CNS.
Term
Where does cerebellar output go?
Definition
From the deep nuclei to the brainstem and motor cortex (via thalamus).
Term
What is the main input, tract and terminals of the vestibulocerebellum?
Definition
1) Vestibular afferents
2) Vestibulo-cerebellar tract
3) Mossy fibres
Term
What is the main input, tract and terminals of the spinocerebellum?
Definition
1) Spinal cord
2) Spino-cerebellar
3) Mossy fibres
Term
What is the main input, tract and terminals of the cortico-cerebellum?
Definition
1) Cerebral cortex
2) Ponto-cerebellar
3) Mossy fibres
Term
What is the main input, tract and terminals of all three divisions?
Definition
1) Inferior olivary nucleus
2) Olivo-cerebellar (contralateral)
3) Climbing fibres
Term
What are the 4 spino-cerebellar tracts?
Definition
1) Dorsal and ventral spino-cerebellar tracts from the lower limb and trunk
2) Cuneocerebellar and rostral spinocerebellar tracts from the upper limb and trunk.
Term
How do inputs from the cerebral cortex reach the cerebellum?
Definition
Sensorimotor areas project to the pontine nuclei which receives inputs from the spinal cord and brainstem. The pontine nuclei project contralaterally to the cerebellum via the ponto-cerebellar tract.
Term
What is the main input to the inferior olivary nucleus?
Definition
The cerebral cortex.
Term
What is the output, function and what effect would a lesion have in the fastigial nucleus?
Definition
1) Medial descending systems
2) Motor execution
3) Loss of balance; wide gait
Term
What is the output, function and what effect would a lesion have in the interposed nucleus?
Definition
1) Lateral descending systems
2) Motor execution
3) Retention tremor; limb movement deficits
Term
What is the output, function and what effect would a lesion have in the dentate nucleus?
Definition
1) Motor and premotor cortices
2) Motor planning
3) Difficulty with complex movements
Term
What is the output, function and what effect would a lesion have in the vestibulocerebellum?
Definition
1) Vestibular nuclei
2) Balance and eye movements
3) Loss of balance and nystagmus
Term
How do mossy and climbing fibres affect the output of purkinje cells?
Definition
1) Mossy fibres excite granule cells which send parallel fibres to excite a row of purkinje cells (weak)
2) Climbing fibres excite purkinje cells oriented perpendicular to the parallel fibres.
Term
Describe past pointing.
Definition
Overshoot when attempting to touch an object.
Term
Describe intention tremor.
Definition
Increased tremor during movement of hand or foot to a target.
Term
Describe dysdiadochokinesia.
Definition
Difficulty in repeated pronations supinations of the arm.
Term
Describe decomposition of movement.
Definition
Lack of smoothness during multi-joint movement.
Term
Describe scanning speech.
Definition
Speech slow and slurred.
Term
What is the effect of the purkinje cell on the deep nuclei?
Definition
It is inhibitory.
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