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trueger
molec bio
50
Other
Not Applicable
05/24/2006
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Term
chromatin structure
 Definition
-DNA wound around +histones
H2a, H2b, H3, H4 octamers
H1 ties em into 30nm strings
in mitosis -> chromosomes
Term
heterochromatin
 Definition
condensed, inactive
Term
euchromatin
 Definition
less condensed, transcription active
Term
condensed, inactive
 Definition
heterochromatin
Term
less condensed, transcription active
 Definition
euchromatin
Term
transition
 Definition
pur for pur, pyr for pyr
Term
transversion
 Definition
pyr for pur, pur for pyr
Term
pur for pur, pyr for pyr
 Definition
transition
Term
pyr for pur, pur for pyr
 Definition
transversion
Term
degenerate code
 Definition
more than one codon for aa
Term
more than one codon for aa
 Definition
degenerate code
Term
which way do u write?
 Definition
5-3 (add to 3 end)
Term
exonucl acty
 Definition
3-5
Term
5-3
 Definition
which way do u write?
Term
3-5
 Definition
exonucl acty
Term
what degrades the RNA primer?
 Definition
dna pol i
5-3 exo
Term
base excision repair
 Definition
make a break sev bases on the 5 side
remove short strand
pol, ligase
Term
xeroderma pigmentosum
 Definition
def base excis repair
eg uvr ABC
cant fix pyr dimers
dry skin, melanoma etc
AR
Term
ataxia-telangectasia
 Definition
xray sens
Term
blooms syndrome
 Definition
radn sens
Term
fanconis anemia
 Definition
crosslinking ds
Term
skin sens to UV
 Definition
xeroderma pigmentosum
Term
xray sens
 Definition
ataxia-telangectasia
Term
radn sens
 Definition
blooms syndrome
Term
crosslinking ds
 Definition
fanconis anemia
Term
dna repair defects
 Definition
xeroderma pigmentosum
ataxia-telangectasia
blooms syndrome
fanconis anemia
Term
xeroderma pigmentosum
ataxia-telangectasia
blooms syndrome
fanconis anemia
 Definition
dna repair defects
Term
wheres the triphos?
 Definition
5 (hence 5-3 writing)
Term
what direction are proteins written?
 Definition
N-C (5-3)
Term
largest RNA
 Definition
mRNA
Term
most abundant RNA
 Definition
rRNA
Term
smallest RNA
 Definition
tRNA
Term
rna pol 1 makes
 Definition
rRNA
Term
rna pol 2 males
 Definition
mRNA
Term
rna pol 3 makes
 Definition
tRNA
Term
a-amanitin
 Definition
inh RNA pol 2
found in poison shrooms
Term
promoter
 Definition
where RNA pol binds
upstream
Term
enhancer
 Definition
binds TFs -> act
Term
operator
 Definition
binds TFs -> inh
Term
where RNA pol binds
upstream
 Definition
promoter
Term
binds TFs -> act
 Definition
enhancer
Term
binds TFs -> inh
 Definition
operator
Term
what splices?
 Definition
snRNPs
Term
snRNPs
 Definition
what splices?
Term
RNA proc
 Definition
5-cap, polyA tail (3), splicing
occurs in nucl
Term
5-cap, polyA tail (3), splicing
occurs in nucl
 Definition
RNA proc
Term
tRNA
 Definition
aa-ACC at 3' end
Term
tRNA charging
 Definition
aminoacyl-tRNA synth
spec for each codon
reqs 1ATP
that energy is used in elongation
Term
wobble
 Definition
3rd position: ambigious (degenerate)
Term
protein synth
 Definition
met binds P site
incoming binds A site
A hijacks met
everyone moves twds E
uncharged tRNA is now in E, peptide is in P, and it repeats
uses GTP to move
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