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Trelbie Bouchard
Medical terminology
20
Medical
Not Applicable
08/29/2021

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Term
Chromosome Breakage
Definition
the breaking of one or both of the sugar-phosphate chains of a DNA molecule that can be caused by exposure of the molecule to ionizing radiation.
Term
Germ Cells
Definition
Female and Male reproductive cells
Term
Mutation
Definition
Loss or change of a nitrogenous base in the DNA chain
Term
Direct action
Definition
ionization of atoms on essential molecules produced by straight interaction with the incident radiation
Term
Radiation damage is observed on which level?
Definition
Molecular, cellular, and organic systems
Term
Chromosome aberrations result when irradiation occurs?
Definition
Early in interphase
Term
Point mutation
Definition
ionizing radiaiton interacts with a DNA macromolecule and the energy transferred in process of ruptures one of its chemical bonds, severs one of the sugar-phosphate chain side rails, or stands.
Term
RBE
Definition
Relative capabilities of radiation with differing LETs to produce articular biologic reaction
Term
LET
Definition
the average energy deposited per unit length of track
Term
cell survival curve
Definition
classic method of displaying the sensitivity of a particular type of cell to radiation
Term
Covalent cross-links
Definition
Chemical unions created between atom by the single sharing of one or more pairs of electrons
Term
Radiation weighting
Definition
used to calculate the equivalent dose to determine the ability of a dose of any kind of ionizing radiation to cause biologic damage
Term
OER
Definition
ratio of the radiation dose required to cause a biologic response of cells or organisms in an oxygen-deprived environment to the radiation dose required to cause an identical response under normal oxygenated conditions.
Term
radiation biology
Definition
branch of biology concerned with the effects of ionizing radiation on living systems.
Term
where are lymphocytes manufactured in the human body?
Definition
Bone marrow
Term
target theory
Definition
cell dies if the key molecule becomes inactivated as a consequence of exposure to ionizing radiation
Term
indirect action
Definition
multistage process that first involves the production of reactive free radicals that are created by the interaction of radiation with water molecules
Term
apoptosis
Definition
programmed cell death
Term
chromatid aberrations
Definition
irradiation of individual chromatids occurs later in interphase after DNA synthesis has taken place
Term
Law of Bergonie and Tribondeau
Definition
Radio sensitivity of cells is directly proportional their reproductive activity and inversely proportional to their degree of differentiation
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