Term
| What factor in protein synthesis is the eukaryotic initiation factor that binds met-tRNA (initiator tRNA) |
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Definition
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Term
| WHat factor in protein synth in euks binds 40s subunit, anti association factor? |
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Definition
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Term
| what factor in protein synth in euks is the cap binding protein, helps place the mRNA on the 40S subunit with the capped 5' end correctly oriented |
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Definition
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Term
| What factor in protein synth in euks is the elongation factor that bring aminoacyl tRNA to the A site? |
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Definition
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Term
| What factor in protein synth of euks is the elongation factor (translocase: moves the ribosome along the mRNA) |
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Definition
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Term
| What ribosomal inhibitor inhibits peptidyl transferase on the prokaryotic large subunit? |
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Definition
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Term
| What ribosomal inhibitor inhibits peptidyl transferase on the eukaryotic large subunit? |
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Definition
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Term
| What ribosomal inhibitor inhibits translocation by the prokaryotic large subunit? |
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Definition
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Term
| What ribosomal inhibitor is an aminoacyl-tRNA analog that causes premature chain termination in prokaryotes and eukaryotes? |
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Definition
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Term
| What ribosomal inhibitor causes mRNA misreading and inhibits chain initiation in prokaryotes? |
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Definition
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Term
| What ribosomal inhibitor inhibits the binding of aminoacyl-tRNAs to the prokaryotic small subunit? |
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Definition
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Term
| What ribosomal inhibitor catalytically inactivates eEF-2 by ADP ribosylation? |
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Definition
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Term
| What ribosomal inhibitor is a poisonous plant protein that catalytically inactivates the eukaryotic large subunit |
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Definition
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Term
| Prokaryotes have how many release factors in the termination of protein synthesis? |
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Definition
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Term
| In prokaryotes RF-1 (release factor 1) recognizes what two stop codons? |
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Definition
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Term
| What two stop codons does RF-2 recognize? |
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Definition
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Term
RF-3 stimulates what two things?
RF-3 also has what kind of activity? |
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Definition
RF-1 and RF-2
GTPase activity |
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Term
| How many release factors do eukaryotes have? |
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Definition
| 1 RF it is called eRF-1 and it recognizes all 3 stop codons |
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Term
| What are the 3 stop codons in protein synthesis? |
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Definition
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Term
| What is the total number of codons for amino acids? |
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Definition
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Term
| What is the total number of codons in genetic code? (this includes codons for termination) |
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Definition
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Term
| What type of mutations involve a change in a single base pair and thus a change in the corresponding mRNA? |
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Definition
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Term
| What type of mutations are detected by gene sequence determination? THERE IS NO CHANGE IN THE AMINO ACID SEQUENCE!!!!! |
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Definition
| Silent mutations (shhh lolz!) |
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Term
| What type of mutations arise from a base change that causes incorporation of a different amino acid in the encoded protein? (ex. hemoglobin and sickle cell disease) |
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Definition
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Term
| What type of mutations arise from point mutations that result in the formation or loss of a termination codon. The resulting protein maybe truncated (shorter) or "read through" (lose stop codon and makes it longer). |
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Definition
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Term
| What type of mutation is generally much more serious and will cause a change all the way down a DNA sequence, making each codon (or every group of three bases) a different sequence, not just in one point or base like a point mutation, that would only slightly change the sequence of a single codon. A frameshift mutation happens not when a DNA base is simply changed, but when a whole base is added or deleted from the sequence of DNA. Causing the codon sets of 3 bases to be out of frame |
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Definition
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Term
| What type of mutation results in the switch of one purine for one pyrimidine? |
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Definition
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Term
| What type of mutation results in a switch of one purine for a different purine OR one pyrimidine for another pyrimidine? |
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Definition
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Term
| Direction of translation in protein biosynthesis is what? |
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Definition
| amino terminal to carboxy terminal |
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Term
| In protein synthesis it reads mRNA in a what direction? |
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Definition
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Term
| In PROKARYOTES, what makes sure ribosome is very close to the AUG start site (features PURINE rich sequence) |
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Definition
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Term
What start signal to both eukaryotes and prokaryotes have?
What start signal is unique to prokaryotes? |
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Definition
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Term
What is the initiator tRNA for proks?
What is the initiator tRNA for Euks? |
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Definition
N-formylmethionine (fMet)
Methionine |
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Term
| Elongation factors for proks? |
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Definition
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Term
| Elongation factors for euks? |
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Definition
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Term
| What are the termination factors for proks? |
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Definition
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Term
| How many termination factors do euks have? |
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Definition
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