Term
mRNA determines the sequence of ? |
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Definition
The amino acids in the protein that is produced. |
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Term
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Definition
many ribosomes attached simultaneously to a single molecule of mRNA |
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Term
What is the initiation codon? |
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Definition
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Term
What provides the energy for chain elongation? |
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Definition
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Term
Proteins are synthesized in what direction? |
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Definition
N- to C- terminus, following codons of mRNA in a 5' to 3' direction. |
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Definition
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Definition
variability in the 3bp spot. there are more than 61 tRNAs |
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Definition
a change that specifies the same amino acid |
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Term
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Definition
a change that specifies a different amino acid |
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Term
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Definition
change that produces a stop codon |
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Term
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Definition
Frameshift! Addition of one or more bases |
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Term
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Definition
Frameshift, loss of one or more bases |
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Term
Frame shifts often cause? |
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Definition
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Term
What are the 4 major processed in translation? |
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Definition
1. tRNA charging 2. Initiation 3. Elongation 4. Termination |
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Term
Sickle Cell Anemia is the result of what kind of mutation? |
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Definition
Missense, Val is made instead of Glu making the hemoglobin hydrophobic |
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Term
Each Amino acids reacts with _ to form _? |
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Definition
ATP, aminoacyl-AMP and pyrophosphate |
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Term
Cleavage of this drives the reaction forming aminoacyl-tRNAs? |
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Definition
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Term
Once the AA is attached to the tRNA insertion of the aa on to a polypeptide chain depends on ? |
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Definition
the codon-anticodon interaction |
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Term
Initiation in prokaryotes. |
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Definition
Shine-Delgarno upstream from the start site |
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Term
What is required to form the initiation complex? |
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Definition
Inititation factors (IF-1, IF-2, IF-3 in prok, eIF-1, eIF-2... in euk,) ATP and GTP |
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