Term
| Physiologic effects of drug metabolism |
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Definition
| Absorption, distribution, metabolism, excretion |
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Term
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Definition
| Formaldehyde to formic acid |
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Term
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Definition
| Acetaldehyde, acetic acid |
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Term
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Definition
| Benzoylecgonine, Ecgonine methyl ester |
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Term
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Definition
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Term
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Definition
| non polar stationary phase and polar mobile phase |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| Depression, bipolar disorder |
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Term
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Definition
| Asthma and pulmonary disease |
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Term
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Definition
| Drug crosses cell membranes of GI tract and enters blood |
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Term
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Definition
| Drug enters blood and reaches equilibrium btwn body fluid compartments. Free drug reaches site of action |
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Term
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Definition
| Takes place mostly in liver. Drugs detoxified by oxidation, reduction, hydrolysis or addition of chemical groups mainly glucuronides and sulfates. Each successive pass through the liver makes drug more water soluble |
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Term
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Definition
| Urinary excretion major elimination pathway of drug and metabolites |
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