• Salivation
• Lacrimation
• Urination
• Diaphoresis

SSRI

(Serotonin Syndrome)

• Hyperreflexia
• Myoclonus
• Hyoerthrrmia
• Autonomic Instability

Tricyclic Antidepressants

(e.g.- imipramine)

• Coma
• Convulsions
• Prolonged QRS

• Respiratory Failure
• Miosis

Sympathomimetic Agents

(e.g.- Cocaine, amphetamines)

• Sweating
• Tremulousness
• Hyperactivity
• Dilated Pupils

Hallucinogenics

(e.g.- Phencyclidine, LSD)

• Visual and sensory distortions

Anticholinergics

(e.g.-Antihistamines, antispasmodics)

• Agitation
• Hallucinations
• Dilated Pupils
• Dry Skin
• Fever
• Flushing

• Foot Drop
• Hemorrhagic cystitis
• Mucosal ulceration
• Infertility later in life

• Pulmonary fibrosis
• Neurotoxicity
• Foot Drop
• CN palsies
• Loss of DTR's

• Hypocalcemia 2° to hypomagnesemia
• High-frequency Hearing Loss
• Bone Marrowo Suppression
• Renal tubular toxicity leading to wasting of
• Potassium
• Phosphorus
• Magnesium (w/2º hypocalcemia)

• Diabetes Insipidus

• Congestive Heart Failure

(dose-dependent cardiomyopathy)

• Tics

• Weight Loss
• Hypothyroidism
• Diabetes Insipidus
• Mild Renal Insufficiency

• Hemorrhagic cystitis

• Pancreatitis
• Coagulopathy (↓fibrinogen and protein C)
• Acute Thrombosis
• Anaphylaxis

Inhibits protein synthesis

• Rhabdomyolysis

• Leukopenia

• Hypocalcemia

• Gallstones
• Pancreatitis
• Hypokalemia/Hyponatremia
• Nephrocalcinosis

• Gingival Hyperplasia

• Renal Tubular Acidosis (RTA)
• Nephrolithiasas

• Positive ANA
• SLE

• Hyperactivity
• Learning Difficulty

Verapamil

(Calcium-channel blocker)

• First Degree Heart Block

• Thrombocytopenia

Hydrochlorothiazide

(Thiazide Diuretic)

• Increased Uric Acid/Gout
• Hypokalemia
• HYPERcalcemia (calcium-sparing diuretic)

Ethanol

(Also the antidote for Methanol Poisoning)