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Toxicology
Ass. clinical Sciences
44
Health Care
Professional
07/17/2013

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Cards

Term
Process of a substance getting into the body
Definition
Absorption
Term
Contact with substance that occurs once or for a short time
Definition
Acute exposure
Term
Response to exposure that equals the sum of the responses
Definition
Additive effect
Term
Change in body function that leads to disease
Definition
Adverse effect
Term
Response to exposure that is less than expected
Definition
Antagonistic
Term
Risk of getting cancer if exposed every day for 70 years
Definition
Cancer risk
Term
Substance that causes cancer
Definition
Carcinogen
Term
Amount of substance present in a certain amount of water etc
Definition
Concentration
Term
Substance present in environment that does not belong there
Definition
Contaminant
Term
Measurement of exposure often expressed as mg/kg body wt
Definition
Dose
Term
United States Environmental Protection Agency
Definition
EPA
Term
Contact with a substance by swallowing, breathing or skin
Definition
Exposure
Term
Water beneath the earth’s surface between the soil and rocks
Definition
Groundwater
Term
Time it takes for half of the original amount to disappear
Definition
Half-life
Term
Source of potential harm from past, current or future exposure
Definition
Hazard
Term
Experiment done in an artificial environment like in a lab
Definition
In vitro
Term
Experiment done within a living organism
Definition
In vivo
Term
Lowest dose of substance introduced by any route other than inhalation which has been reported to have caused death in humans or animals
Definition
Lethal dose 0
Term
Dose of a substance which is expected to cause the death of 50 percent of an entire defined experimental animal population
Definition
Lethal dose 50
Term
Lowest observed adverse effect level
Definition
LOAEL
Term
Lowest dose of a substance that has been reported to cause harmful effects in people or animals
Definition
LOAEL
Term
Conversion or breakdown of a substance by a living organism
Definition
Metabolism
Term
Any product of metabolism
Definition
Metabolite
Term
Minimal risk level
Definition
MRL
Term
Dose of a substance below which it is unlikely to cause harm
Definition
MRL
Term
Substance which causes genetic damage [mutations]
Definition
Mutagen
Term
Damage to DNA, genes or chromosomes of living organisms
Definition
Mutation
Term
Highest tested dose that has been reported to have no adverse effects on people or animals
Definition
NOAEL
Term
Place when one is exposed to a substance in the environment
Definition
Point of exposure
Term
Group or number of people living in a specified area or sharing a similar characteristic such as age or occupation
Definition
Population
Term
Action that reduces the risk of developing a disease
Definition
Prevention
Term
Systematic collection of information on persons with a specific disease or exposed to a specific substance
Definition
Registry
Term
Probability that something will cause harm or injury
Definition
Risk
Term
Step taken to reduce the chance of people getting the disease
Definition
Risk reduction
Term
Ways people come into contact with a hazardous substance:
a. Inhalation
b. Ingestion
c. Absorption
Definition
Routes of exposure
Term
Biological response to multiple substances where one substance enhances the effect of another. The combined effect is greater than the sum of the individual effects
Definition
Synergistic effect
Term
Substance which causes fetal developmental defects
Definition
Teratogen
Term
Agent that cases harmful effects to living organisms
Definition
Toxin
Term
Any substance which injures or kills living things
Definition
Toxicant
Term
One who studies the effects of toxins on living things
Definition
Toxicologist
Term
Clinical, forensic, industrial, environmental, regulatory
Definition
Toxicology types
Term
Volatile organic compound
Definition
VOC
Term
Organic compounds which evaporate readily into the air
Definition
VOCs
Term
Benzene, toluene, Methylene chloride
Definition
VOC examples
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