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Toxicology
grad level tox review
7
Other
Professional
03/23/2012

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Cards

Term
TCDD toxicity?
Definition
hepatocellular carcinoma in female sprague rats
agent orange contaminant
potent carcinogen, but not a mutagen
Term
first example of PAH carcinogenicity
Definition
scrotal cancer among chimney sweepers from soot.
Term
TOCP - triorthocresyl phosphate - what is it? what is the toxici effect?
Definition
used in bootleg liquor during prohibition, caused ginger-jake walk - neurotoxicant
Term
sulfanilamide use and effect
Definition
used to combat bacterial diseease, insoluble - so mixed w diethyl glycol as an elixir - patients died of acute renal failure from metbolism to oxalic acid and glycolic acid
Term
thalidomide effect
Definition
serious birth defects
Term
Ah receptor
Definition
high affinity cellular binding protein
Term
toxicology
Definition
the study of adverse effects of xenobiotics and endobiotics
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