Term
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Definition
| capability of a substance to cause an adverse effect |
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Term
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Definition
| the probability that a hazard will occur under specific exposure conditions. |
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Term
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Definition
| Structure/Activity Relationships - theoretical models that can be used to predict the physicochemical, biological and environmental fate properties of molecules. |
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Term
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Definition
| The death of a cell caused by a progressive failure of essential metabolic and structural cell components, usually in the cytoplasm. |
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Term
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Definition
| Individual or single cell death by a process of self-destruction of the cell nucleus. |
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Term
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Definition
| The study of the time-dependent processes related to toxicants as the interact with living organism. |
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Term
| Cytochrome P450 Reductase |
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Definition
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Term
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Definition
Glucuronidation - Look for (COO-) - UDP-GA
Sulfation/(Sulfonation) - SO3 - PAPS
Acetylation - CH3-C=0 - Acetyl coenzyme A
Methylation - CH3 - SAM |
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Term
| Perfusion-Limited Compartments |
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Definition
| Occurs when the cell membrane permeability is much greater than the blood flow rate. |
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Term
| Diffusion-Limited Compartments |
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Definition
| occurs when the flux or transportation of xenobiotics across the cell membrane is slow compared with blood flow. |
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