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1. Inhalation of particles can lead to _____. |
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2. Pneumoconiosis is most commonly causes by _____ or _____. |
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3. _____ and _____ are associated with asbestos exposure, particularly in conjunction with cigarette smoking. |
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Definition
BRONCHIAL CANCER AND MESOTHELIOMA |
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4. _____ means the same thing as bronchial cancer. |
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5. Does asbestos exposure cause lung cancer or mesothelioma more commonly? |
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6. _____ absorb other toxins, such as polycyclic aromatic hydrocarbons, and deliver them to the respiratory tract. |
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7. Particulates increase ones susceptibility to _____ and _____. |
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PULMONARY DYSFUNCTION AND DISEASE |
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8. Particulates may yield _____ in the lungs that develop over years of exposure. |
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9. _____ is any lung disease such as anthracosis or silicosis, due to permanent deposition of substantial amounts of particulate matter in the lung. |
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10. _____ is a pneumoconiosis that is usually asymptomatic due to deposition of coal dust in the lungs. |
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11. In coal workers pneumoconiosis (anthracosis) there is deposition of dust that produces _____ around the bronchioles, occasionally causing focal _____. |
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Definition
DUST-LADEN MACROPHAGES; BROCHIOLAR EMPHYSEMA |
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12. Coal workers pneumoconiosis usually causes no symptoms, but can progress to _____ with impaired lung function. |
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Definition
PROGRESSIVE MASSIVE FIBROSIS |
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13. In coal workers pneumoconiosis, _____ are the phagocytic cell that engulf the carbon particle, and then It dies and is embedded in the periphery of the lung. |
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14. Coal dust provides a sufficient stimulus for the macrophages to release these 4 factors, which are important in the inflammation and fibrosis of coal workers pneumoconiosis. |
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1) ENZYMES, 2) CYTOKINES, 3) OXYGEN RADICALS, 4) FIBROBLAST GROWTH |
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15. In the past 10 years, over _____ American miners have died from coal workers pneumoconiosis. |
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16. _____ is a combination of rheumatoid arthritis and pneumoconiosis that displays as intrapulmonary nodules which are homogenous and distinct on a chest x-ray. |
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17. _____ is inflammation and scarring of the lungs in people with rheumatoid arthritis who have been exposed to mining dust. |
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18. It is believe that a _____ and _____ are thought to be aggravating factors of Caplan’s syndrome. |
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Definition
GENETIC PREDISPOSITION; SMOKING |
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19. 4 differential diagnoses of Caplan’s syndrome. |
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Definition
1) PULMONARY TB, 2) SARCOIDOSIS, 3) BROCHOGENIC PNEUMONIA, 4) SILICOSIS |
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20. 4 tests used to diagnose Caplan’s syndrome. |
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1) CHEST X-RAY, 2) LUNG FUNCTION TEST, 3) RHEUMATOID ARTHRITIS, 4) ANTINUCLEAR ANTIBODY |
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21. The treatment of Caplan’s syndrome is with _____, and the patient must avoid all exposure to _____. |
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22. _____ is caused by the inhalation of crystalline-free silica dust. |
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Definition
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23. Silicosis is characterized by _____. |
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Definition
NODULAR PULMONARY FIBROSIS |
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24. Chronic silicosis initially causes _____ symptoms, or only mild _____. |
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Definition
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25. over the years, silicosis can cause these 4 conditions. |
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Definition
1) DYSPNEA, 2) HYPOXEMIA, 3) PULMONARY HYPERTENSION, 4) RESPIRATORY IMPAIRMENT |
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26. the diagnosis of silicosis is based on _____ and _____. |
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Definition
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27. there is no effective treatment for silicosis except for _____, and for severe cases one may receive a _____. |
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Definition
SUPPORTIVE CARE; LUNG TRANSPLANT |
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28. _____ is any of several fibrous mineral forms of magnesium silicate, which is a grayish mineral whose fibers can be woven into a fireproof fabric. |
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29. 4 industries and trades with a proven ling with asbestos. |
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Definition
1) CONSTRUCTION, 2) MINING AND MILLING, 3) PRODUCTION OF FRICTION PRODUCTS AND CEMENT, 4) SHIP BREAKING INDUSTRY |
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30. 3 primary affected sites of asbestosis. |
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Definition
1) BRONCHUS, 2) PERITONEUM, 3) PLEURA |
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31. After a latent period of 15-20 years a patient exposed to toxic levels of asbestos may develop one of more of the following 6 diseases. |
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1) ASBESTIOSIS, 2) PLEURAL PLAQUES, 3) PLEURAL EFFUSION, 4) LUNG CANCER, 5) MESOTHELIOMA, 6) GI CANCER |
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32. Asbestosis forming pleural plaques typically affects the _____. |
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33. 5 ways to avoid asbestos toxicity. |
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1) PREVENTION OF EXPOSURE, 2) STOP SMOKING, 3) OBSERVE WORKPLACE CONTROL MEASURES, 4) WEAR PROTECTIVE EQUIPMENT, 5) WATER DOWN DRIED MATERIAL |
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34. _____ is an allergic disease usually caused by breathing in the dust of moldy hay. |
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35. What is the prevention of farmers lung. |
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Definition
AVOIDANCE OF DUSTY ENVIORNMENT AND MOLDY HAY |
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36. _____ is a form of reactive airway disease characterized by bronchoconstriction in cotton, flax, and hemp workers. |
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37. Symptoms of byssinosis are _____ and _____ that worsen on the 1st day of the work week, and subside as the week progresses. |
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Definition
CHEST TIGHTNESS AND DYSPNEA |
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38. Diagnosis of byssinosis is based on _____ and _____. |
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Definition
HISTORY; PULMONARY FUNCTION TESTS |
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39. _____ patients have an increased chance of developing byssinosis. |
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Definition
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40. 2 treatments of byssinosis. |
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Definition
1) AVOIDANCE OF EXPOSURE, 2) USE OF ANTI-ASTHMA DRUGS |
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41. If a patient has a FEV:FVC1 ratio under _____%, they may have byssinosis. |
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42. _____ is a type of lung disease due to inhalation of dust from the residue of cane after the extraction of cancer. |
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43. Bagassosis is also associated with manufacturing _____ and _____. |
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44. It has been suggested that bagassosis is due to the synergistic action of _____ and _____ and that in the pathogenesis of the syndrome an immunological component may be involved. |
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Definition
BAGASSE FIBERS, AND MICROPOLYSPORA FAENI |
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45. Bagassosis is an occupational lung disease of the extrinsic allergic alveolitis type, caused by breathing dusts containing _____ which grow in stored, moldy bagasse. |
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Definition
SPORES OF THERMOPHILIC ACTINOMYCETES |
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46. Bagassosis is a type of occupational disease due to _____. |
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47. Pigeon breeder’s lung, humidifier or air conditioner lung, mushroom pickers lung, maple bark disease, and duck fever are all _____ immune complex pathogenesis for the early lesion followed by a _____ delayed hypersensitivity reaction. |
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Definition
TYPE 3; TYPE IV DELAYED HYPERSENSITIVITY REACTION |
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