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Toxicities and Side Effects
Boards
40
Pharmacology
Professional
05/04/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
Anti-Muscarinic
Definition
Tricyclics (Amitryptiline)
Term
Coronary Vasospasm
Definition
Cocaine, Sumatriptan (5HT1D blocker)
Term
Cutaneous Flushing
Definition
Niacin, Vancomycin, Adenosine, Ca2+ Channel blockers
Term
Dilated Cardiomyopathy
Definition
Doxo/Daunorubicin (prevent with Desrazoxane)
Term
Torsades de Pointes
Definition

Class 1a ant-arrhythmics (quinidine, procainide, disopyramide)

-Class III (Sotalol, Bretylium, ibutilide, Amiodarone)

-Cisapride (5HT4 agonist- ^ GI motility)

Term
Agranulocytosis
Definition
Clozapine, Carbamazepine, Colchicine, Propylthiouracil, Methimazole
Term
Aplastic Anemia
Definition

-Chloramphenicol

-Benzene

-NSAIDS

-Propylthiouracil, Methimazole

Term
Direct Coombs-positive hemolytic anemia
Definition
Methyldopa
Term
Gray Baby Syndrome
Definition
Chloramphenicol
Term
Hemolysis in G-6-PD deficiency
Definition

-Malaria drugs (Primaquine)

-Sulfonamids

-Isoniazid

-Aspirin

-Ibuprofen

-Nitrofurantoin (ab for UTI)

Term
Megaloblastic Anemia
Definition

-Methotrexate

-Phenytoin

-Sulfa drugs

Term
Cough
Definition
ACE inhibitors
Term
Pulmonary Fibrosis
Definition
Amiodarone, Busulfan, Bleomycin
Term
Acute Cholestatic hepatitis
Definition
Macrolides
Term
Massive Hepatic Necrosis
Definition
Acetaminophen, Halothane, Phalloides Mushroom, Valproate
Term
Hepatitis
Definition
Isoniazid
Term
C. Diff infection
Definition
Clindamycin, Ampicillin
Term
Adrenocortical insufficiency
Definition
Glucocorticoid withdrawal
Term
Gynecomastia
Definition

Spironolactone, Digitalis, Cimetidine, Alcohol, Ketoconazole

Some Drugs Create Awesome Knockers

Term
Hot Flashes
Definition
Tamoxifen, Clomiphene (anti-estrogens)
Term
Gingival Hyperplasia
Definition
Phenytoin
Term
Gout
Definition
Thiazide diuretics, Furosemide
Term
Osteoporosis
Definition
Corticosteroids, Heparin
Term
Photosensitivity
Definition
Sulfonamides, Amiodarone, Tetracycline
Term
Rash (Steven's Johnson)
Definition
Penicillin, Lamotrigine, Sulfa drugs, Ethosuximide, Carbamazepine, Phenobarbital, Phenytoin, Allopurinol
Term
SLE-like syndrome
Definition
Procainide, Hydralazine, Isoniazid, Phenytoin
Term
Tendonitis/Tendon rupture
Definition
Fluoroquinolones
Term
Fanconi's sydrome
Definition
Expired Tetracyclines
Term
Interstitial Nephritis
Definition
 Methicillin, NSAIDS, Furosemide
Term
Hemorrhagic Cystitis
Definition
Cyclophosphamide, ifosfamide
Term
Cinchonism
Definition
Quinidine, Quinine
Term
Diabetes Insipidus
Definition
Lithium, demeclocycline
Term
Parkinson-like syndrome
Definition

Potent Typical Anti-Psychotics (Haloperidol, Fluphenazine)

-Reserpine

-Metoclopramide

 

Term
Seizures
Definition
Bupropion, imipenem/cilastatin, isoniazid
Term
Bisulfiram-like rxn
Definition

Metronidazole, Procarbazine (anti-neoplastic alkalater), 1st generation sulfonylureas (Telbutamide, Chlorpropamide)

 

Term
Nephro/Oto toxicity
Definition
Aminoglycosides, Vancomycin, Loop diuretics, cisplatin (protect w/ amifostine)
Term
P450 inducers
Definition

Quinidine

Barbiturates

St. John's Wort

Phenytoin

Rifampin

Griseofulvin

Carbamazepine

 

Term
P450 Blockers
Definition

Ketoconazole

Erythromycin

Grapefruit Juice

Sulfonamides

Isoniazid

Cimetidine

Ritonivir

Ciprofloxacin

Term
Sulfa drugs
Definition
Celecoxib, Furosemide, Probenicid, thiazides, TMP-SMX, sulfasalazine, sulfonylureas, sumatriptan
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