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Topic 3 Key Words
Edexcel; Voice of the Genome
29
Biology
12th Grade
12/28/2012

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Term
Smooth endoplasmic reticulum
Definition
no ribosomes attached, makes lipids and steroids
Term
Rough endoplasmic reticulum
Definition
Interconnected membrane-bound, flattened sacs found in the cytoplasm of eukaryotes, with ribosomes attached to the outer surface.
Term
Protein trafficking
Definition
The process by which proteins are moved to where they are needed, and/or secreted from the cell.
Term
chiasma
Definition
The visible manifestation of crossing over between homologous chromosomes. The point where the chromatids break and rejoin during the first prophase of meiosis.
Term
generative nucleus
Definition
The generative nucleus divides to form two haploid male gametes which move down the pollen tube.
Term
polar nuclei
Definition
The two polar nuclei in the embryo sac fuse with one of the male gametes to form a triploid cell. The triploid cell divides to form the endosperm.
Term
Radicle
Definition
Young root
Term
Plumule
Definition
Young shoot
Term
Cotyledons
Definition
Seed leaves
Term
Endosperm
Definition
Storage tissue in the seed.
Term
Testa
Definition
Seed coat
Term
G1 phase
Definition
First gap phase between the end of mitosis and the onset of the S phase
Term
S phase
Definition
The stage of interphase during which the DNA is replicated
Term
G2 phase
Definition
Second gap phase, between the S phase and mitosis
Term
Prophase
Definition
The first stage of nuclear division during which the chromosomes become thicker and shorter to form chromatids, joined together by a centromere. The Spindle forms and the nuclear membrane breaks down.
Term
Metaphase
Definition
The stage of nuclear division at which the chromosomes line up in one plane. The Centromeres are attached to spindle fibres
Term
Anaphase
Definition
The stage of nuclear division where the spindle fibres shorten, pulling chromatids to each pole. The spindle then breaks down.
Term
Telophase
Definition
The final stage of nuclear division where the chromosomes
become diffuse and the nuclear membrane reforms
Term
Chromatin
Definition
The nucleic acid-protein complex found in eukaryotic chromosomes
Term
Blastocyst
Definition
Hollow ball of cells surrounding a central cavity, formed five days after conception.
Term
cDNA
Definition
Complementary DNA made using an RNA template and the enzyme reverse transcriptase.
Term
Promoter
Definition
The region of DNA, upstream of the coding part of the gene, that acts as the initial biding site for RNA polymerase
Term
Regulator protein
Definition
A protein which attaches to RNA polymerase and a promoter region – required for transcription to be initiated.
Term
Repressor protein
Definition
Molecules (often proteins) which prevent transcription in a variety of ways, e.g. by binding to the promoter region and blocking transcription.
Term
Signal Proteins
Definition
Can be hormones, growth factors or other regulatory molecules which switch on gene transcription.
Term
meristem
Definition
Area of undifferentiated plant cells where cell division will form specialized plant organs.
Term
p53
Definition
A tumour suppressor gene which inhibits the CDKs at the G1/S transition and therefore stops the cell cycle.
Term
BRCA1
Definition
A gene which normally produces a protein which repairs DNA. Mutated in some cases of breast cancer.
Term
BRCA2
Definition
A second breast cancer gene, found on chromosome 13, which has a DNA repair function.
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