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Topic 14
Structure and Orginization of Nucleic Acids
12
Biology
Undergraduate 1
04/14/2012

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Term
Nucleotides
Definition
Composed of:
-Pentose Sugar.
-Nitrogenous base.
-Phosphate group.
Term
Phosphodiester Bonds
Definition
Link nucleotides.
Term
Original Thoughts About Genetic Information
Definition
It was originally thought that the protiens of a cell might provide the genetic code.
Term
Chargaff's Rule
Definition
A = T
C = G
Term
Frederick Griffith
Definition
Tried to find the identity of genetic material in 1928.
Term
Hershey and Chase
Definition
Conducted work with bacteriophages to determine if DNA or protein was the genetic material in 1952.
Term
Rosalind Franklin
Definition
Used X-Ray crystallography to analyze the structure of DNA.
Term
Watson and Crick
Definition
Created the DNA model (double helix). A:T and C:G are know as Watson-Crick base pairs (complimentary base pairs).
Term
Antiparallel
Definition
Complementary DNA strands run in opposite directions.
Term
Major and Minor Grooves
Definition
Indents in double helix DNA structure.
Term
Pentose Sugar
Definition
Nitrogenous base is linked to the 1-prime carbon and the phosphate group is linked to the five prime carbon.
Term
Nucleic Acid Polymer
Definition
Run from 3' end (OH) to 5' end (phosphate group).
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