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b-lacam/b-lactamase inhibitor, semisynthetic (amino-penicilling with enhanced uptake through porin channels due to pos charge) |
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IV 3rd/4th gen, pseudomonas aeruginosa coverage |
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B-Lactam antibiotic from thienamycin Cilastatin inhibits dehydropeptidase-1, an enzyme that metabolizes imipenem. Without it, imipenem would cause toxicity to the proximal tubule. |
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IV 3rd gen ceph, serious gram neg organisms, penetrates CSF |
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IV B-lactamase inhibitor (tazo), Semisynthetic 4th generation, Systemic pseudomonas infections |
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synthetic oxazolidinone, PO/IV, gram Pos activity used in VRE cases |
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broad spectrum penicillin |
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2nd gen: ampicillin, amoxicillin, 3rd gen: carbenicillin, ticarcillin, 4th gen: piperacillin |
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clavulanate, sulbactam, tazobactam and avilbactam |
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ampicillin, amoxicillin, bacampicillin |
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nafcillin, oxacillin, cloxacillin, and dicloxacillin |
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ureidopenicillins (azlocillin, mezlocillin, piperacillin), carboxypenicillins (ticarcillin, carbenicillin) and mecilinam |
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