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| BRAND: Cleocin CLASS: Lincosamide antibiotic INDICATIONS: Bacterial infectious disease (infections due to anaerobic organisms) Staph/Strep/Pneumococci, Infection of skin/SubQ tissue, Lower resp tract infection, Pelvic inflammatory disease, Septicemia MOA: A semisny 7-chloro, 7-deoxylincomycin deriavitative active agains Gram +, except: enterococci and C. difficile. Gram - aerobes are resistant but most anaerobes are sensitive. Inhibits protein synthesis by binding to 50s ribosomal subunit. DOSAGE FORM: Cap |
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| BRAND: Zithromax CLASS: Macrolide antibiotic INDICATIONS: Acute infective exacerbation of COPD (skin or tissue infection), Bacterial sinusitis, Chancroid nongonococcal cervicitis/urethritis, Community acquired pneumonia, Gonorrhea, Strep pheryngitis MOA: Macrolide antibiotic, slightly less active than eythromycin, against Gram +, more active on Moraxella, catarrhails, Haemophilus p. Legionella, Neisseria, Bordetella, Mycoplasma, chlamydia trachomatis. DOSAGE FORM: Tab, Suspension, Powder for oral susp |
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| BRAND: Biaxin CLASS: Macrolide antibiotic INDICATIONS: Acute infective COPD exacerbation, Community acquired pneumonia/skin infection/sinusitis/pharyngitis, Disseminated infection due to mycobacterium avium-inrracellulare group (prophylaxis HIV), H pylori GI tract infection MOA: binds to 50s ribosomal subunits of the 70s ribosomal units, inhbit bacterial RNA depenent protein synthesis DOSAGE FORM: Tab, Susp, Extended release tab |
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| BRAND: Macrodantin CLASS: Nitrofuran antibiotic INDICATIONS: UTI treatment/prophylaxis MOA: A synthetis nitrofun inactivates bacterial ribosomes and active against most bacterial UTIs except, P. aeruginos, Proteus sp, enterobacter, & klebsiella. to prevent recurrent UTIs also uncomplicated UTIs. DOSAGE FORM: Cap, Susp, Ex release cap |
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| BRAND: FLagyl CLASS: Nitroimidazole antibiotic INDICATIONS: Abcess (anaerobic), Amebic dysentery (acute), Bacterial vaginosis, Trichomoniasis MOA: synthetic nitroimidazole active against trichomoniasis, amebiasis, and giardiasis. Bactericidal against all obligate anaerobic bacteria. inactive againts against aerobic and requires microbial reduction of nitroeductase enzyme to disrupt bacterial DNA & inhibit nucleic acid synthesis DOSAGE FORM: Cap, SR Tab, Tab |
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| Trimethoprim(TMP)/Sulfamethoxazole(SMZ) |
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Definition
| BRAND: Bactrim, Septra CLASS: Sulfonamide antibiotic INDICATIONS: Acute infective COPD exacerbation, HIV (pneumocystis pneumonia/prophylaxis of), Traveler's diarrhea, UTI MOA: SMZ; inhbitis the synthesis of dihydropteric acid. TMP; inhibits enzymatic reduction of dihydrofolic acid to tetrahydrofolic acid. vitro activity against MRSA. DOSAGE FORM: Oral tab, Susp |
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| BRAND: Peridex CLASS: Antibacterial cleansing agent INDICATIONS: Gingivitis, Skin cleansing MOA: Antiseptic and antimicrobial with bactericidal activity, Binding of cationic molecule with neg charged bacterial cell walls and extramicrobial complexes DOSAGE FORM: Oral liquid, Oral sol, Topical sol |
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| BRAND: Vibramycin CLASS: Tetracycline antibiotic INDICATIONS: Acinetobacter infection, Acne vulgaris, Gonorrhea, Staph infection of skin MOA: Broad-spectrum bacteriostatic compounds inhibit proten synthesis at 30s ribosomal subunit. active on gram + & - aerobic & anaerobic, spirochetes, myscoplasmas, rickettsiae, chlamydiae, and some protozoa. Most enterobactericae and p aeruginosa resistant. DOSAGE FORM: Powder for susp, Oral tab, Oral cap |
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| BRAND: Minocin CLASS: Tetracycline antibiotic INDICATIONS: Acne vulgaris,Bacterial infection (if allergy to penicillin) MOA: broad spectrum bacteriostatic inhibit protein synthesis at 30s ribosomaol subunits. Active on Gram + & -, aerobic & anaerobic, spriochetes, mycoplasma, rickettsiae, chlyamydiae, & some protozoa. Resisted by enterobacteriacae & p aeruginoas. DOSAGE FORM: Oral tab, Oral tab (ex release), Oral cap |
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| BRAND: Bactroban CLASS: Topical antibacterial INDICATIONS: Impetigo MOA: antibacterial agent active agains Gram + and MRSA. active against certain gram -. inhibits bacterial protein synthesis by reversibly and specifically binding to bacterial isoleucyl transferRNA synthetase. No in vitro cross resistance. DOSAGE FORM: Topical ointment, Topical cream |
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