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Top 30 dental RX
UOP ICS drugs lecture
30
Pharmacology
Graduate
11/19/2011

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Term
HYCD/APAP
Definition
hydrocodone and acetamedphen combination. Sold as vicodin and other things. Hydrocodone is an opioid with issues of tolerance and dependance. Acetamedephen overdose can lead to hepatic necrosis.
Term
Lipitor
Definition
Lowers cholesterol- no dental consideration
Term
Norvasc
Definition
amlopidin- Calcium channel blocker. lowers blood pressure. rare gingical hyperplasia compared to other CCBs
Term
Toprol XL
Definition
Metropolol. Beta 1 blocker. Used to lower HTX and treat angina pectoris
Term
Synthroid
Definition
Levothyroxine- thyroid replacement therapy for patients with hypothyroidism. Beware of the many dental considerations of patients with hypothyroidism.
Term
Zoloft
Definition
Sertraline- antidepressant. SSRI. xeristomia and bruxism reported. no problem with local with epi. Beware of suicide by young people increased.
Term
Amoxicillin
Definition
Broad spectrum antibiotic.
Used for prophalaxyic treatment.
Beware of tightening regulations
Long term use may lead to candidiasis
Term
Lexapro
Definition
Antidepressant SSRI type.
Same dental considerations and suicide cautions as zoloft
Escetalopram
Term
Albuterol
Definition
Beta 2 agonist= bronco-dilator. used for asthma and COPD.
dental consideration is xerestomia
Term
Zocor
Definition
Simvastatin- reduces cholesterol.
no dental considerations
Term
Nexium
Definition
Esomeprazole - proton pump inhibitor - Used for erosive esophagitis; symptomatic gastroesophageal reflux disease (GERD) and as part of a multidrug regimen for Helicobacter pylori eradication in patients - Dental consideration: Can cause xerostomia
Term
Levothyroxine
Definition
Generic - thyroid replacement therapy for patients with hypothyroidism
Term
Ambien
Definition
Zolpidem - Non-benzodiazepine hypnotics - used for insomnia - only dental consideration is xerostomia
Term
Singulair
Definition
Montelukast - Leukotriene Receptor Antagonist - Prophylaxis and chronic treatment of asthma; relief of symptoms of seasonal allergic rhinitis - 2% of patients complain of dental pain related to taking the drug - mechanism is unknown
Term
Prevacid
Definition
Lansoprazole - Proton pump inhibitor - same issues as with Nexium
Term
Plavix
Definition
Clopidogrel - antiplatelet agent- popular term blood thinner - used to prevent MI, Stroke and DVT's - dental considerations covered later in this lecture
Term
Zithromax
Definition
Azithromycin - new macrolide - replaces erythromycin - used for tx of acute otitis media and lower/upper respiratory tract infections and other infections of bacterial origin - dental considerations: no adverse reactions reported
Term
Fosamax
Definition
Bisphosphonate - used for osteoporosis - dental considerations are related to osteonecrosis of the jaws and is covered later
Term
Zyrtec
Definition
Cetirizine - antihistamine used for allergy - may cause changes in salivary flow
Term
Advair diskus
Definition
Fluticasone and Salmeterol - inhalation steroid - maintenance tx of astma and COPD. Dental considerations: May cause localized infections with Candida albicans or Aspergillus niger have occurred frequently in the mouth and pharynx with repetitive use of oral inhaler of corticosteroids
Term
Protonix
Definition
Pantoprazole - proton pump inhibitor - used for GERD, but no dental considerations in contrast to Nexium and Prevacid
Term
Furosemide
Definition
Loop diuretic - management of oedema associated withe CHF and hepatic and renal disease or alone or in combination with other drugs for htx - no dental considerations
Term
Atenolol
Definition
Beta 1 blocker used for tx of htx, post MI or angina pectoris - no dental considerations because of selective beta 1 blocking except to avoid prolonged use of NSAID's, which can reduce the antihypertensive effect of the beta 1 blocker
Term
Effexor
Definition
Venlafaxine - Serotonin/Norepinephrine Reuptake Inhibitor (SNRI) - tx of anxiety and panic disorder - ignificant xerostomia (normal salivary flow resumes upon discontinuation); may contribute to oral discomfort, especially in the elderly; taste perversion. Although venlafaxine is not a tricyclic antidepressant, it does block norepinephrine reuptake within CNS synapses as part of its mechanisms. It has been suggested that vasoconstrictor be administered with caution and to monitor vital signs in dental patients taking antidepressants that affect norepinephrine in this way.
Term
Warfarin
Definition
Coumadin -"blood thinner" - Used for prophylaxis and treatment of thromboembolic disorders including those after replacement of valves or coming from atrial fibrillation or from an MI - dental considerations are covered elsewhere, but where briefly: The art of doing nothing!
Term
Cephalexin
Definition
First generation cephalosporin (antibiotic) used for respiratory tract infections, otitis media, skin and skin structure infections, bone infections, and genitourinary tract infections. No special dental considerations except 20% cross allergy reaction with penicillin only when the allergic reaction was immediate
Term
Flonase
Definition
Fluticasone - corticosteriod for inhalation - used prophylactically for astma and non-allergic rhinitis - only dental consideration is the possibility for localzed candida infections
Term
Oxycodone/APAP
Definition
Schedule II opioid (narcotic) - same concerns with APAP as HYCD/APAP. Also consider misuse by overprescribing. Street name oxy, OC and illbilly heroin
Term
Levaquin
Definition
Levofloxacin - Quinolone antibiotic, Treatment of mild, moderate, or severe infections caused by susceptible organisms. Includes the treatment of community-acquired pneumonia, including multidrug resistant strains of S. pneumoniae (MDRSP); nosocomial pneumonia; chronic bronchitis. Dental consideration: Use epi with great care because Lavequin prolongs the QT interval and the effect of epi on that is uncertain at this time.
Term
Diovan
Definition
Valsartan - Angiotensin II Receptor Blocker - used for hypertension - no dental considerations
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