Term
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Definition
Fosamax®
Class: Bisphosphonate
MOA: Inhibits bone resorption via actions osteoclasts or on osteoclast precursors; decreases the rate of bone resorption, leading to an indirect increase in bone mineral density
Pregnancy: C |
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Term
Side Effects of Alendronate |
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Definition
Common SE: abdominal pain, acid regurgitation, nausea, dyspepsia, constipation, diarrhea, musculoskeletal pain, flatulence, photosensitivty |
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Term
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Definition
Zantac®
Class: H2 Anatagonist
MOA: Competative inhibition of histamine at H2 receptors of the gastric parietal cells, which inhibits gastric acid secretion, gastric volume, and hydrogen ion concentration are reduced. Does not affect pepsin secretion, pentagastrin-stimulated intrinsic factor secretion, or serum gastrin
Pregnancy: B |
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Term
Side Effects of Ranitidine HCl |
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Definition
Common SE: headache, diarrhea constipation, muscle aches, vertigo, malaise, dizziness, dry mouth, dry skin, nausea, vomiting, rash, confusion, fatigue |
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Term
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Definition
Mobic®
Class: NSAID
MOA: Reversibly inhibits cyclooxygenase-1 and 2 (COX-1 and 2) enzymes, which result in decreased formation of prostaglandin precursors; has antipyretic, analgesic, and anti-inflammatory properties
Pregnancy: C/D (3rd trimester) |
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Term
Side Effects of Meloxicam |
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Definition
Common SE: dyspepsia, nausea, abdominal pain, diarrhea, rash, urticaria, dizziness, somnolence, elevated liver transaminases, fluid retention, edema, tinnitus, bruising, photosensitivity |
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Term
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Definition
Diastat®, Valium®
Class: Benzodiazepine
MOA: Binds to stereospecific benzodiazepine receptors on the post synaptic GABA neuron at several sites within the CNS, including the limbic system, reticular formation. Enhancement of the inhibitory effect of GABA on neuronal excitability results by increased neuronal membrane permeability to chloride ions. The shift in chloride ions results in hyperpolarization (a less excitable state) and stabilization
Pregnancy: D
Schedule: C-IV |
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Term
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Definition
Common SE: drowsiness, fatigue, ataxia, confusion, depression, joint pain, headache, tremor, dystonia, amnesia, urinary retention, constipation, nausea, incontinence, diplopia, dizziness, irritability, disinhibition, libido changes, rash, dry mouth, hypersalivation, menstrual irregularities, hypotension, elevated liver transaminases |
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Term
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Definition
Aleve®, Anaprox®, Naprelan®, Naprosyn®
Class: NSAID
MOA: Reversibly inhibits cyclooxygenase-1 and 2 (COX-1 and 2) enzymes, which result in decreased formation of prostaglandin precursors; has antipyretic, analgesic, and anti-inflammatory properties
Pregnancy: C/D (3rd trimester) |
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Term
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Definition
Common SE: dyspepsia, nausea, abdominal pain, constipation, headache, dizziness, drowsiness, rash, elevated liver transaminases, fluid retention, tinnitus, bruising, dyspnea, photosensitivity |
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Term
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Definition
Darvocet-N®
Class: Opioid Analgesic Combination
MOA: Binds to opiate receptors to inhibits ascending pain pathways. It blocks pain perception in in the cerebral cortex by binding tp specific receptor molecules within the neuronal membranes of synapses.
Pregnancy: C
Schedule: C-IV
REMOVED FROM MARKET IN NOV 2010 B/C OF INCREASED CARDIAC ARRHYTHMIAS |
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Term
Side Effects of Propoxyphene-N/APAP |
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Definition
Common SE: dizziness, sedation, nausea/vomiting, constipation, abdominal pain, rash, lightheadedness, headache, weakness, euphoria, dysphoria, visual disturbances, CNS stimulation, confusion, itching, elevated LFTs, urinary retention, biliary spasm |
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Term
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Definition
Diflucan®
Class: Antifungal
MOA: Interferes with fungal cytochrome P450 activity, decreasing ergosterol synthesis and inhibiting cell membrane formation
Pregnancy: C |
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Term
Side Effects of Fluconazole |
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Definition
Common SE: nausea, headache, rash, vomiting, abdominal pain, diarrhea, dyspepsia, taste changes, dizziness, elevated liver transaminases |
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Term
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Definition
Medrol®
Class: Corticosteroid
MOA: Decreases inflammation by suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability
Pregnancy: C |
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Term
Side Effects of Methylprednisolone |
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Definition
Common SE: sodium and fluid retention, increased sweating, headache, vertigo, insomnia, nervousness, mood swings, edema, muscle weakness, elevated BP, glucose intolerance, bruising, menstrual irregularities, hypokalemia, increased IOP, impaired wound healing, Cushing syndrome, skin picmentation abnormality, hirsutism, itching |
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Term
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Definition
Adoxa®, Doryx®, Doxy-100®, Monodox®, Oracea®, Periostat®, Vibramycin®
Class: Tetracycline
MOA: Inhibits protein synthesis by binding with the 30S and possibly the 50S ribosomal subunit of susceptible bacteria; may also cause alterations in the cytoplasmic membrane
Pregnancy: D |
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Term
Side Effects of Doxycycline |
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Definition
Common SE: headache, nausea, dyspepsia, joint pain, diarrhea, URI, rash, dysmenorrhea, photosensitivity, vulvovaginal candidiasis, skin/tissue discoloration, elevated BUN |
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Term
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Definition
Paxil®, Paxil CR®, Pexeva®
Class: SSRI
MOA: Selective serotonin reuptake inhibitor, chemically unrelated to tricyclic, tetracyclic, or other antidepressants; presumably, the inhibition of serotonin reuptake from brain synapse stimulated serotonin activity in the brain
Pregnancy: D |
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Term
Side Effects of Paroxetine |
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Definition
Common SE: nausea, somnolence, headache, dizziness, constipation, decreased libido, diarrhea, sweating, dry mouth, ejaculatory dysfunction, tremor, anorexia, nervousness, anxiety, abnormal vision |
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