Term
|
Definition
-Clopidogrel
-Antiplatelet
-*inhibits platelet aggregation by blocking ADP
-tx reduction of thrombotic events (stoke, heart attack)
-*aspirin inc bleeding risk
-*report unusual bleeding/dark urine |
|
|
Term
|
Definition
-Filgrastim
-GCSF
-tx dec incidence of infection in *myelosuppressive chemo
-regulates production of neutriphils
-IV or SQ |
|
|
Term
|
Definition
-Pegfilgrastin
-*GCSF
-tx dec incidence of infection in *myelosuppressive chemo
-PBPC collection
-regulates production of neutriphils
-SQ |
|
|
Term
|
Definition
-Epoetin Alfa
-Erythropoietin
-tx anemia
-(inc RBC production
-IV and SQ |
|
|
Term
|
Definition
-Darbepoetin Alfa
-Erythropoietin
-Anemia
-*inc RBC production
-DOA longer than Epogen
-IV and SQ? |
|
|
Term
|
Definition
-Heparin
-Unfractionated Heparin
-tx thrombosis/coagulopathis
-*binds to antithrombin
-risk of bloeeding
-IV SQ
-often with Coumadin |
|
|
Term
|
Definition
-Rosuvastatin
-HMG-CoA Reductase Inhibitors
-tx various dyslipidemia
-inc toxicity with drugs that inhibit CYP3A4
-10mg daily
-avoid grapefruit juice |
|
|
Term
|
Definition
-Atorvastatin
-HMG-CoA Reductase inhibitors
-tx various dyslipidemia
-inc tox with CYP3A4 inhibitor
-avoid grapefruit juice |
|
|
Term
|
Definition
-Pravastatin
-HMG-CoA reductase inhibitor
-various dyslipidemia
-inc tox with CYP3A4 inhibitor
-40 mg daily
-avoid grapefruit juice
-take in evening |
|
|
Term
|
Definition
-Fluvastatin
-HMG-CoA reductase inhibitor
-inc tox with CYP3A4 inhibitors
-20 mg daily
-avoid grapefruit juice |
|
|
