Oxcarbazepine

-Anticonvulsants

-Treats seizures, bipolar disorder, neuropathic pain

-Drowsiness, dizziness

Phenobarbital (CIV)

-Anticonvulsants

-Treats seizures, used as sedative

-Avoid alcohol

Phenytoin

-Anticonvulsants

-Treats seizures

-Decreases levels of oral contraceptive

-SJS/TEN risk (skin diseases)

Active seizure: 15-20mg/kg (max rate 50mg/min)

Maintenance: 100mg tid or 300mg qd

-Avoid alcohol

Pregabalin (CV)

-Anticonvulsant

-Treats seizures, diabetic neuropathy, fibromyalgia

-Causes drowsiness

-Tell doctor about swelling or pain

Topiramate

-Anticonvulsant

-Treats seizures, migraines

-Avoid other CNS meds. and alcohol

Valproic acid

-Anticonvulsant

-Treats seizures, bipolar, and migrain prophylaxis

-Increases blood conc. of many other meds

-Monitor for liver damage

Bupropion

-Antidepressant

-Treatment of depression

-May cause headache, insomnia

Mirtazapine

-Antidepressant

-Treats depression

-Causes drowsiness

Serzone

(Removed from market as brand name)

Nefazodone

-Antidepressant

-Treatment of depression, used as sedative

-Causes sedation, headaches, hepatotoxicity

Trazadone

-Antidepressant

-Treats depression, used as sedative

-Causes dizziness, drowsiness

Duloxetine

-Serotonin-norepinephrine reuptake inhibitor

-Treats depression, GAD, pain syndrome

-Do not stoop taking abruptly

-May take 2-3 weeks for max effect

Effexor

Effexor XR

Venlafaxine

-Serotonin-norepinephrine reuptake inhibitor

-Treats depression, GAD, SAD

-Do not stoop taking abruptly

-Monitor blood pressure

-Children should not use

Citalopram

-SSRI

-Treats depression, OCD

-Tapper off over 2 weeks

-Start elderly at half dose

Escitalopram oxalate

-SSRI

-Treats depression, GAD

-Tapper off over 2 weeks

-Start elderly at half dose

Prozac

Sarafem

Fluoxetine

-SSRI

-Treats depression, OCD, panic disorder

(Sarafem)

Initial: 10-20mg/day, can be adjusted every 2 weeks

MDD = 80mg/day

Take in the morning

Paroxetine

-SSRI

-Treats depression

-May take weeks before improvement

-Causes insomnia, suicidal thoughts

Sertraline

-SSRI

-Treats depression, PTSD, SAD, OCD

-Start elderly at half dose

25-200mg/day

Amitriptyline

-Tricyclic antidepressant

-Treats depression, neuropathic pain, migraine prophylaxis

-Increase dose gradually every 2-3 weeks

-Start elderly at half dose

Doxepin

-Tricyclic antidepressant

-Treats depression, pruritic skin condition

-Take at bedtime

-Start elderly at half dose

Nortriptyline
-Tricyclic antidepressant

-Treats depression

-Anticholinergic and sedation effects can occur

Lithium carbonate Lithium citrate

-Antimanic agent

-Treats bipolar disorder, refractory depression

-Sodium intake increases lithium excretion

-MAOIs possible severe CNS reactions

-Monitor drug concentration

Aripiprazole

-Antipsychotic agent, atypical

-Treats schizophrenia, bipolar, MDD

-Affects multiple NTs

-CYP450 inhibitors increase effects

-Avoid alcohol

-Do not double a dose if a dose is missed

Olanzapine

-Antipsychotic agent

-Treats schizophrenia, bipolar, alzheimer's

-Effects multiple CNS NTs

-CYP1A2

-Causes drowsiness

-Avoid alcohol

Initial 5-10mg qd can be increased over 1-2 weeks to 15-20mg qd MDD of 20mg often exceeded to 30mg

Quetiapine

-Antipsychotic agent

-Treats schizophrenia, bipolar, depression

-Effects multiple CNS NTs

-CYP3A4

-Causes drowsiness

-Avoid alcohol

Risperidone

-Antipsychotic agent

-Treats schizophrenia, bipolar

-Effects multiple CNS NTs

-CYP2D6

-Causes drowsiness

Ziprasidone

-Antipsychotic agent

-Treats schizophrenia, bipolar

-Effects multiple CNS NTs

-"Azole's" increase effects

-Causes drowsiness

Donepezil

-Cholinesterase inhibitors

-Treats dementia, ADHD

-Inhibits acetylcholinesterase

Take 5mg hs (may increase to 10mg hs after 4-6 weeks)

Carbidopa/Levodopa

-Dopamine agonist

-Treats parkinson's, restless leg syndrome,

amblyopia (poor vision)

-MAOIs increase effect

-Antipsychotics decrease effect

-May take several weeks/months

-Avoid high protein diets and Vit B6

Ropinirole

-Dopamine agonist

-Treats parkinson's, RLS

-CYP 1A2

-MAOIs and estrogen derivatives increase

-Antipsychotics decrease effects

-Titrate dosing

Temazepam (CIV)

-Sedative-hypnotic agent, Benzodiazepine

-Short term treatment of insomnia, anxiety, panic attacks

-Oral contraceptives decrease concentration

-Avoid alcohol

-Use only 7-10 days to prevent addiction