Abilify

Aripiprazole

tablet, oral and IM solutions, ODT Discmelt

Schizophrenia, Bipolar (atypical antipsychotic)

CYP interactions - increase dose 50% with enzyme inducers, decrease dose 50% with enzyme inhibitors

potentiates antihypertensives

QT prolongation/akathisia

BBW: suicidal thoughts in teens and children

Accutane

Isotretinoin

acne vulgaris and cystic, various cancers (cervical, head and neck, CML)

retinoid intracrine/paracrine reduction in size of sebaceous glands

IPLEDGE: pregnancy test, only 30 days at a time

avoid retinoids (Vit A), OCs, MTX, TCNs, Warfarin

take with food or milk

BBW: pregnancy, breastfeeding, papilledema

Actos

Pioglitazone

Diabetes

thiazolidindione

CYP interactions - gatifloxacin, OCs

contraindications: class 3 or 4 HF

monitor LFTs prior to initiation and periodically thereafter (DC if ALT >2.5 x upper limit of normal)

BBW: edema

weight gain common

Adderall (XR)

Amphetamine/Dextroamphetamine salts

ADHD and narcolepsy

BBW: CV events - acute MI, arrhythmias, CVD

BBW: increased risk of substance abuse

S/E: anorexia, HTN, glaucoma

avoid late evening doses

caution with other meds that increase NE and DA

Advair

Salmeterol/Fluticasone

Asthma and COPD

Beta 2 agonist and steroid

caution with use of BB and other beta agonist medications

rinse mouth after each use to avoid thrush

Advil/Motrin/Caldolor

Ibuprofen

pain (NSAID)

reversible inhibition of COX1 and COX2

avoid in severe hepatic impairment and anuria

caution with ACEI and ARBs

BBW: do not use after bypass surgery, can cause GI bleeds, could cause fatal MI or stroke

avoid use in 3rd trimester of pregnancy

Aldactone

Spironolactone

edema, HTN, hypokalemia

caution with other K-sparing medications (ACEI, ARBs)

S/E: hyperkalemia, renal failure, diabetic neuropathy, anuria, breast tenderness and menstrual irregularities, GI disturbances

Alphagan (P)

Brimonidine

glaucoma, ocular HTN

alpha-2 agonist (decreases IOP)

use caution in pregnancy and heart disease

wait at least 10 mins between use if using other eye medication, may increase sensitivity to light

Altace

Ramipril

HTN (ACEI)

prodrug

renal adjustment required, caution with other K sparing medications

contraindication in pregnancy and RAS

S/E: angioedema, hyperkalemia, cough

Amaryl

Glimepiride

Diabetes (Sulfonylurea)

adjust for CrCl <22 mL/min

can cause hypoglycemia (eat regular meals), weight gain

small chance of cross reaction with sulfonamide allergy

Ambien/Zolpmist/Edluar

Zolpidem

insomnia

adjust for hepatic impairment

retrograde amnesia

interactions: protease inhibitors, CNS depressants

Amitiza

Lubiprostone

Constipation, IBS

fatty acid that acts locally in the GI as Cl channel activator, increase intestinal secretion and motility

contraindications: GI obstruction

abdominal/chest pain, diarrhea, fecal incontinence, flushing, HA, edema, N/V, hyperhidrosis

Apidra

Insulin glulisine

rapid acting insulin

filtered by kidneys, adjust for CrCl< 50

should eat within 15 mins of admin

Contraindications: coma, continuous infusion, DKA, hypoglycemia 

Aranesp

Darbapoetin alfa

anemia (stimulates erythropoiesis)

contraindications: albumin, hamster hypersensitivity, red cell aplasia

S/E: HA, fever, fatigue, muscle/joint pain, N/V/D

Argatroban

Argatroban

DVT, pumonary embolism (direct thrombin inhibitor)

excreted via biliary tract, hepatically adjust

monitor PTT and signs of bleeding

contraindications: any bleeding (GI, intracranial)

Aricept

Donepezil

ODT tablet

Alzheimer's (acetylcholinesterase inhibitor)

metabolism increased by phenytoin, carbamazepine, phenobarbital, rifampin, dexamethazone

metabolism may be decreased by ketoconazole, quinidine

Contraindications: breastfeeding, children, caution in pts with sick sinus syndrome due to vagotonic effects on heart, may increase acid secretion caution in pts prone to ulcers, caution in pts with asthma or COPD

take in evening right before bed

Arimidex

Anastrazole

breast cancer (aromatase inhibitor)

monitor bone mineral density, LDL

S/E: hot flashes, osteoporosis

Arixtra

Fondaparinux

DVT, pulmonary embolism

selective inhibition of factor Xa

unbound drug excreted in urine, renally adjust

monitor anti-Xa activity in selected pts

contraindications: bleeding, IM admin, renal failure

Asacol/Lialda/Apriso

Mesalamine

mild to moderate ulcerative colitis

(salicylate)

caution in renal dysfunction or pyloric stenosis

swallow whole, do not crush

Apriso - do not take with antacids

lialda - take with meal

Aspirin

Aspirin

pain, antiplatelet

irreversible COX 1 and 2 inhibition

renally adjust CrCl <10, avoid in severe hepatic impairment

caution in children (Reye's syndrome)

varicella vaccination - salicylates should be avoided 6 weeks after vaccination

Ativan

Lorazepam

anxiety, sedation, alcohol withdrawal (BZD)

Contraindications: narrow angle glaucoma, caution in primary depression, psychosis, impaired renal or hepatic function, pregnancy, breastfeeding, COPD, coma, alcohol intoxication, shock, sleep apnea

do not D/C abruptly

Augmentin XR

amoxicillin/clavulanate

infection (beta lactam)

distributes into CNS if meninges inflamed, renally adjust

bacteriocidal

probenicid will decrease renal excretion

Avelox

Moxifloxacin

infection (FQ)

chelation interactions

concominant NSAIDs can lower the seizure threshold

Contraindications: QT prolongation, hypokalemia/magnesmia, patients on class 1A or class 3 antiarryhthmics, tendon pain

tendon rupture possible

not renally excreted, not for UTI

Bactrim/Septra (DS)

Sulfamethoxazole/Trimethoprim

infection (folic acid synthesis inhibitor)

renally adjust CrCl <30

contraindications: pregnancy, megaloblastic anemia, infants <2 months, G6PD deficient hemolytic anemia

S/E: Stevens-Johnson syndrome, photosensitivity, megaloblastic anemia, kernicterus in children

Bactroban

Mupirocin

topical cream/ointment, nasal oitment

skin infections, protection from MRSA colonization

for external use only, avoid eyes

Boniva

Ibandronate

IV, PO

osteoporosis

take 60 mins before breakfast with full glass of water, remain upright for 60mins after use

do not use in CrCl< 30

Buspar

Buspirone

general anxiety disorder

extensive 1st pass, adjust with renal or hepatic impairment

3A4 inducers/inhibitors

MAOI, SSRI, trazodone - serotonin syndrome

Byetta

Exenatide

Diabetes (GLP-1 mimetic)

dose adjust in renal impairment CrCl<50

delays gastric emptying, so take other medications 1 hour prior

administer 30 mins before meals, drink plenty of water

Bystolic

nebivolol

HTN (selective B1 blocker)

Contraindications: 1st degree heart block, severe hepatic impairment

may maks signs of hypoglycemia in diabetic patients

Cardizem (CD)/Cartia/Dilacor/Tiazac

Diltiazem

HTN, A fib (nonDHP-CCB)

hepatic metabolims, extensive first pass

3A4 interactions (carbamazepine, phenytoin, phenobarb - inducers)

contraindications: systolic HF

S/E: bradycardia, constipation

Cardura (XL)

Doxazosin

HTN, BPH (alpha 1 blocker - vasodilation)

do not use with PDE5 inhibitors

S/E: orthostatic hypotension

take at bedtime

Catapress

clonidine

patch, tablet, solution for injection

HTN (alpha 2 agonist)

hepatic metabolism, undergoes enterohepatic recycling

monitor closely in renal disease

S/E: drowsiness, dizziness, erythema, dry mouth, nocturia, postural hypotension

take at bedtime

Celebrex

Celecoxib

pain (COX2 inhibitor)

decreased GI intolerance over NSAIDs, but increased cardiac problems

BBW: coronary artery bypass, graft surgery, GI bleeds, increased risk of stroke or MI

caution in patients with sulfa allergy

CellCept

mycophenolate

antirejection agent (for transplant)

renally adjust

pregnancy category D

take 1 hour before or 2 hours after meals (other medication esp. antacids, cholestyramine)

increased risk of infections

Chantix

Varencicline

Smoking cessation

renally adjust CrCl< 30

BBW: suicidal thoughts, depression

S/E: nightmares, abdominal pain, constipation, flatulence, n/v, HA, insomnia

Cipro

Ciprofloxacin

infection (FQ)

does not cover S. pneumo

partial hepatic metabolism, renal adjustments required

BBW: tendon rupture (not recommended in those <18 or >65)

chelation interactions (can turn poo orange), QT prolongation, glucose disturbances

Claritin D

Loratidine/pseudoephedrine

allergies, nasal/sinus congestion

50% of dose with CrCl <30, avoid in hepatic impairment

pseudophed - increased BP and glucose and thyroid disturbances

loratidine - dryness, confusion in elderly

Cleocin

Clindamycin

capsules, vaginal cream and suppository, topical solution, granules for oral solution

infection (gm+ anerobes)

hepatic metabolism, no adjustments unless severe hepatic impairment

BBW: diarrhea, pseudomembranous colitis

Clozaril

Clozapine

refractory schizoprenia, bipolar, tremor in Parkinson's

(atypical antipsychotic)

extensive hepatic metabolism

highest amount of weight gain, glucose, lipids, sedation, hypotension

BBW: risk of seizures, agranulocytosis, myocarditis, respiratory effects

pharmacy and physician have to be registered to dispense, product has to be drop shipped

Colchicine

Colchicine

Anti-gout

enterohepatic recycling, biliary excretion, do not use in renal or hepatic impairment

low purine diet, avoid alcohol

interactions: HMG-CoA inhibitors, P-glycoprotein inhibitors

Combivent/Duoneb

albuterol/ipratropium

COPD (albuterol- B2 agonist, ipratropium - Ach inhibition)

Contraindications: peanut-oil, soya lecithin allergy, caution in heart disease, angioedema

S/E: dry mucous membranes, palpiations, dizziness, URTI, nasal congestion, rhinitis, A fib, HTN

Concerta/Ritalin/Focalin XR

Methylphenidate, Dexmethylphenidate

ADHD, narcolepsy

avoid caffeine and other stimulants

contraindications: anxiety, glaugoma, MAOI therapy

S/E: weight loss, HA, upset stomach, allergic reaction, anxiety, chest pain, irregular heart beat, high BP, unusual bleeding

Cordarone

Amiodarone

ventricular fibrilation/tachycardia

S/E: photosensitivity, blue skin, impaired memory, thyroid dysfunction, halo vision, bradycardia, pulmonary fibrosis

BBW: arrhythmias, liver dysfunction

get regular lab, eye exams, cardiac tests

Coreg

Carvedilol

HTN (alpha-beta blocker)

caution in severe liver or respiratory impairment and pregnancy (2nd and 3rd trimesters)

can mask signs of hypoglycemia

Cortisporin Otic

Neomycin, Polymyxin B, hydrocortisone

otic solution/suspension

ear infection

S/E: dryness, irritation, burning, ototoxicity (if ear drum not intact)

Cosopt

Timolol, Dorzolamide

Glaucoma (timolol - BB, dorzolamide - carbonic anhydrase inhibitor)

S/E burning, stinging, itching, blurred vision, keratitis

Coumadin/Jantoven

warfarin

anticoagulation

monitor INR, PT, signs of bleeding

2C9 and 3A4

S/E: cholesterol embolus, bleeding, tissue necrosis, hemorrhage, hepatitis

keep Vit K intake consistent

Cozaar

Losartan

HTN (ARB)

first pass metabolism, active metabolite, hepatic and renal adjustment

Contraindications: renal artery stenosis, pregnancy

S/E: hypotension, cough, diarrhea, hypoglycemia, rhabdomyolysis, anemia, angioedema

Cubicin

Daptomycin

infection (no lung coverage)

excreted unchanged in urine, renally adjust

monitor CPK weekly

S/E: myalgias

Cymbalta

Duloxetine

anxiety, depression, diabetic neuropathy, fibromyalgia (SNRI)

do not use in CrCl <30 or hepatic impairment

Contraindications: alcoholism, hepatic disease, MAOI therapy, uncontrolled narrow angle glaucoma

S/E: somnolence, dizziness, HA, insomnia, n/d, HTN

medication requires tapper for D/C

Demadex

Torsemide

HTN, edema (loop diuretic)

CYP2C9 metabolism

monitor ins and outs and electrolytes

Contraindications: anuria, sulfa allergy

S/E: HA, electrolyte abnormalities (hyperglycemia, hypokalemia, hyperuricemia), othostatic hypotension

Depakote (ER)

Divalproex (valproic acid)

seirures, bipolar

monitor serum levels

inhibits metabolism of lamotrigine, phenytoin, carbamazepine, phenoparb, warfarin

induces metabolism of phenytoin, phenobarb, carbamazepine

PB interactions - warfarin, phenytoin, ASA

Contraindications: hepatic disease, pancreatitis, urea cycle disorders

BBW: teratogenic, hepatic failure, pancreatitis

Desyrel

Trazodone

depression, sleep

avoid MAOIs and linezolid within 14 days of tx

S/E: dizziness, HE, sedation, nausea, blurred vision, priapism, othostasis

tapper

take at bedtime

Detrol LA

tolterodine

overactive bladder

renally and hepatically adjust

anticholinergic effects (dryness)

Diflucan

fluconazole

fungal infection

renally adjust

astemizole, cisapride, eletriptan, pimozide, ranolazine, red yeast rice, terfenadine

S/E: setvens johnson synrome, GI disturbances, liver dysfunction, alopecia, leuko/neutro/thombo cytopenia

Dilantin

phenytoin

seizure

monitor closely - LFTs, EEG, neurologic function, serum albumin, serum phenytoin (target 10-20), BP

induces: cyclosporine, warfarin, protease inhibitors, CS, OC, lamotrigine, phenobarb, carbamazepine, VA

inhibited by - cimetidine, fluconazole, isoniazid, VA

induced by: antacids, carbamazepine, phenobarb, continuous enteral tube feedings

PB interactions: VA, warfarin, salicylates

S/E: ataxia, nystagmus, behavior changes, sedation, dizziness, neurotoxic, hirtuism, gingival hyperplasia, rash, hepatotoxicity, folate deficeincy,  agranulocytosis

Dilaudid

Hydromorphone

pain

monitor BP, respiratory status

S/E: bradycardia, constipation, hypotension, respiratory depression, drowsiness

Diovan

Valsartan

HTN (ARB)

renally adjust

caution with other potassium sparing medications

contraindications: bilateral renal artery stenosis, pregnancy, breastfeeding

S/E: angioedema, hyperkalemia, acute renal failure, blood dyscrasias

Diprivan/ (Lusedra)

Propofol/ (Fopropofol)

anasthesia

hepatic metabolism, highly fat soluble

monitor BP, blood gasses, progression into cardiac/renal failure, Zn after 5 days of tx, serum TG

contraindications: egg or soy allergy

S/E: hypotension, apnea, high TG, cardiac changes, flu-like symptoms

Duragesic/Actiq

fentanyl

transdermal patch, lozenge

pain

avoid in opioid naive patients

do not cut patch

Dyazide/Maxzide

triamterene, HCTZ

HTN (K-sparing diuretic, thiazide)

contraindications: anuria, diabetic nephropathy, renal disease, sulfonamide hypersensitivity

S/E: photosensitivity, electrolyte disturbances, GI disturbances, rash, dizziness

Effexor (XR)/ Pristiq

venlafaxine/ desvenlafaxine

depression, anxiety (SNRI)

renally and hepatically adjust

CYP2D6 and 3A interactions

do not take within 14 days of MAOI therapy

S/E: increased BP, sexual dysfunction, suicidal thoughts, HA, insomnia, somnolence, GI disturbances, tremor, aggitation, weight loss

takes several weeks to see full effects

Effient

Pasugrel

anticoagulation (GP2b/3a inhibitor)

monitor Hgb, Hct

avoid in pts with TIA or stroke hx

S/E: HA, hyperlipidemia, nausea, hemorrhage, dizziness

Elavil

Amitriptyline

depression (TCA)

lots of interactions

avoid with any drugs that can cause serotonin syndrome

Contraindications: acute MI, AV block, MAOI therapy, QT prolongation, elderly, BPH, closed angle glaucoma

S/E: sexual dysfunction, suicidal thoughts, dizziness, GI disturbances, agitation, weight gain, dryness 

Elimite/Nix

permethrin

lice

Contraindications: hypersensitivity to chrysanthemums, patients <2 months

S/E: pruitis, erythema, burning, numbness, edema, difficulty breathing in pts with asthma

Epogen/Procrit

Epoetin

anemia

monitor Hgb 2x/week then 2-4 times a month, BP 3x/wk, serum ferritin monthly, transferrin saturation monthly then q3 months

variable stability in NS

S/E: may increase risk of CV or thrombolic events

Evista

Raloxifene

osteoporosis, breast cancer prevention (SERM)

contraindications: hx of thrombolic events, pregnancy, breastfeeding, immobilized pts

Fiorcet

APAP, butalbital, caffeine

headache

renally and hepatically adjust

S/E: CNS depression, hepatotoxicity, N/V

Flagyl

Metronidazole

cream, gel (topical and vaginal), capsule, infusion, lotion, tablet, ER tablet

infection including anaerobes

hepatically and renally adjust

contraindications: pregnancy, HF, blood dyscrasias, H pylori, hepatic/renal disease

S/E: CNS effects (seizures, neuropathies), C. diff superinfections

protect solution from sunlight

avoid alcohol (disulfram reactions)

Flexeril

Cyclobenzaprine

muscle relaxant

avoid in hepatic impairment

contraindications: hyperthyroidism, MAOI, HF, arrhythmias, heart block, post MI

S/E: CNS depression, dryness (esp. dry mouth)

Flomax

tamsulosin

 BPH (alpha 1 agonist)

caution with concurrent PDE5 inhibitors

Contraindications: sulfonamide allergy

S/E: orthostasis, abnormal ejaculation, chest pain, decreased libido, blurred vision

Flonase

fluticasone

allergies

use caution in hepatic impairment

do not use if infection or atrophy is present

folic acid

folacin, Pteroylglutamic acid, folate

IM, IV, SC, oral

tx of anemia

may turn urine yellow

S/E: allergic rxn, bronchospasm, flushing, malaise, pruritis

Foradil/ (brovana)

formoterol/ (aformoterol)

COPD, asthma (long acting B2 agonist)

BBW: may increase incidence of asthma related death

S/E: palpatations, diarrhea, nausea, xerostomia, restlessness

Fosamax

alendronate

osteoporosis

contraindications: hypocalcemia, esophageal abnormalities, inability to sit up for at least 30 minutes

S/E: vomiting, GI upset, HA, alopecia, esophageal irritation, hypocalcemia, jaw necrosis

take at least 30 minutes before food with a full glass of water

infections (AMG)

renally adjust

avoid use during pregnancy

S/E: nephrotoxicity, neurotoxicity, ototoxicity, neuromuscular blockade

Glucophage

metformin

diabetes

do not use SrCr >1.4 in women or >1.5 in men

avoid in CrCl <60ml/min

avoid in hepatic failure

contraindications: renal impairment, metabolic acidosis

BBW: lactic acidosis - risk increased with renal impairment

avoid in pts >80 due to lactic acidosis

Glucotrol XL

glipizide

diabetes (sulfolnylurea)

adjust for CrCl <10 and hepatic impairment

contraindications: sulfa allergy, ketoacidosis, type1 DM

S/E: hypoglycemia, GI upset, dizziness, HA, stevens-johnson, weight gain

Humalog

insulin lispro

rapid acting insulin

excreted by kidneys, adjust for CrCl <50

HydroDiuril

HCTZ

HTN (thiazide)

adjust for renal and hepatic disease

S/E: hypotension, photosensitivity, electrolyte abnormalities, hyperglycemia, hyperuricemia, GI upset, cardiac disturbances, pancreatitis, stevens-johnson

take in morning to avoid nocturia

Imdur

Isosorbide mononitrate

angina

avoid PDE5 inhibitors

contraindications: glaucoma, head trauma, hemorrhage, anemia

S/E: HA, dizziness, hypotension, tachycardia, constipation, N/V

Imitrex/Sumavel/Trexmeit

Sumatriptan (w/ naproxen in trexmiet)

migraine

hepatic metabolism and first pass, hepatically adjust

contraindications: ischemic heart disease, uncontrolled HTN, erogts or serotonin agonist w/i 24hrs, MAOI w/i 14 days

BBW: increased risk of thrombotic events, increased risk of NSAID GI irritation

Inderal (LA)

Propranolol

HTN (nonselective BB)

hepatic CYP and first pass metabolism, hepatically adjust

BBW: taper doses slowly to avoid rebound HTN and tachycardia

masks signs of hypoglycemia

Infed/Venofer

Iron Dextran/Iron Sucrose

must do test dose of iron dextran for hypersensitivity

BBW: anaphylactic reactions

S/E: rash, N/V/D, arthragia, hypotension, HA

Isoptin/Calan (SR)

verapamil

HTN (non-DHP CCB)

CYP metabolism, hepatically adjust

Contraindications: A fib, cardiogenic shock, HF, 2nd and 3rd degree heart block, symptomatic hypotension

S/E: edema, hypotension, dizziness, HA, constipation, N/V, peripheral edema

Januvia

Sitagliptan

diabetes (DPP-IV inhibitor- increases incretin)

mostly excreted unchanged in urine and feces, renally adjust CrCl < 50

Keflex

Cephalexin

infection (1st gen ceph)

excreted unchanged in urine, adjust for CrCl <50

Keppra

Levetiracetam

seizures

66% excreted unchanged in urine, adjust for CrCl <80

no known drug interactions!

S/E: vomiting, anorexia, dizziness, HA, nervous/hostile behavior, depression, fatigue, rhinitis, pharyngitis

Lactulose/ Enulose

lactulose

hepatic encephalopathy, constipation

poor systemic absorption, degraded via colonic flora

Contraindications: galactosemia, pts requiring a galactose free diet

causes GI upset

may affect absorption of other drugs

Lamictal

Lamotrigine

Bipolar, seizures

renally and hepatically adjust

induced by phenobarb, phenytoin, carbamazepine

inhibited by VA

BBW: skin rash esp. with VA

S/E: rash, diarrhea, N/V, ataxia, dizziness, coordination problems, HA, blurred vision, anxiety, depression, dysmenorrhea, rhinitis

Lamisil

Terbinafine

fungal infections

renally and hepatically adjust

Lanoxin

Digoxin

A fib

renally adjust

interactions: amiodarone, BZDs, propafenone, cyclosporine, dilt/verapamil (dig toxicity)

BB: additive effects on HR

drugs which cause hypokalemia potentiate dig toxicity

contraindications: ventricular fibrulation

S/E: changes in cardiac rhythm, GI disturbances, CNS changes, ocular problems, changes in K, anorexia

Lantus

insulin glargine

long acting insulin (once daily)

renally adjust

Lasix

furosemide

edema (Loop)

renally adjust

monitor wt and ins and outs

contraindications: anuria

S/E: hyperglycemia, hearing impairment, interstitial nephritis, hyperuricemia, pancreatitis, dehydration, orthostatic hypotension, hypercholesterolemia, photosensitivty

Levaquin

Levofloxacin

infection (FQ)

concentration dependent, renally adjust

chelation reactions, use with warfarin can increase INR, drugs that increase QT interval should be avoided

contraindications: torsades de pointes, QT prolongation, tendon pain

S/E: hepatotoxicity, glucose disturbances, cyrstaluria, GI intolerance, tendon rupture, QT prolongation 

Levemir

Insulin Detemir

long acting insulin

binds to albumin and dissociates over time, renally adjust

once or twice daily dosing

Lexapro

escitalopram

depression (SSRI)

hepatically adjust

monitor LFTs and thyroid function

not as many interactions as other SSRIs

contraindications: MAOI w/i 2 wks

S/E: tremor, agitation, GI upset, Gi bleeding, sexual dysfunction, sleep disturbances, serotonin syndrome

Lidoderm

Lidocaine

transdermal patch

acute tx of vent arrhythmias, nerve pain, anesthisia

hepatically adjust

drugs that affect rate or rhythm can be effected by lidocaine

contraindications: Adam-strokes, SA/AV block, corn allergy

S/E: respiratory depression, skin irritation, edema, confusion, heart rate or rhythm changes

Lipitor

Atorvastatin

cholesterol

do not use in liver disease

monitor CPK and lipids

3A4 interactions: amiodarone, azoles, cyclosporine, dilt/verapamil, grapefruit juice, erythromycin

contraindications: hepatic disease, rhabdomyolysis, pregnancy

S/E: myopathy, myositis, elevated hepatic transaminases

Lithonate/Lithotabs

lithium

bipolar

renally adjust

monitor serum drug concentrations, thyroid and glucose

ACEI, ARB, thiazides, NSAIDs can cause toxicity

caffeine, theophylline can cause decreased lithium

contraindications: CV disease, renal disease, pregnancy

S/E: n/v, tremor, polydipsia, polyuria, nocturia, weight gain, memory impairment, hypothyroidism, cardiac irregularities

maintain normal salt intake, do not drastically change from day to day and week to week