Term
4 functions of Endothelium |
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Definition
Barrier Function, Antithrombotic activity, Effect on Vascular Tone, Smooth Muscle Cell proliferation. |
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Term
Factors that recruit leukocytes |
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Definition
chemoattractant nature of modified LDL, expression of cytokines by injured endothelial cells (TNF, MCP), Expression of cell adhesion molecules (VCAM-1, ICAM-1). |
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Term
Order of high frequency atheroschlerosis |
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Definition
1. abdominal and iliac arteries 2. proximal coronary arteries 3. thoacic aorta, femoral, popliteal arteries 4. internal carotid arteries 5. vertebral, basilar & middle cerebral arteries. |
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Term
What are signs and symptoms of CAD |
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Definition
dyspnea, diaphoresis, nausea, cool and clammy skin |
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Term
What are the 4 componenets of a lipoprotein? |
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Definition
cholesterol, triglyceride, phospholipid, apoprotein. |
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Term
What are the lipid risk factors for CAD? |
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Definition
increased LDL, increase in apoB, increased Lp (a), decreased HDL, reduction in apo A-I, increased TG |
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Term
Familial hypercholesterolemiz |
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Definition
Defect in gene encoding LDL receptors. Autosomal dominant disorder. |
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Term
3 ways HDL is a therapeutic chemical |
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Definition
increase APO 1 production, promote reverse cholesterol transport, delay catabolism of HDL |
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