Term
| Togaviridae Characteristics |
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Definition
enveloped, ssRNA, positive sense
labile, short incubation
Alphavirus affects domestic animals
two surface glycoproteins classify Alphavirus into serotype
E1-hemagglutination activity
E2-neutralization target |
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Term
| Togaviridae Entry, Replication, Release |
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Definition
receptor mediated endocytosis
replicates in cytoplasm
virus shuts off cell biosynethesis
gets envelope from internal membranes
release by cytoplasmic vesicles then exit via cytolysis |
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Term
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Definition
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Term
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Definition
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Term
| Equine Encephalitis Characteristics |
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Definition
Eastern, Western, and Venezualan
REPORTABLE
zoonotic |
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Term
| Equine Encephalitis Signs |
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Definition
encephalitis
high human mortality
acute febrile neurological disease
biphasic fever |
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Term
| Equine Encephalitis Transmission |
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Definition
mosquito
birds are reservoirs |
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Term
| Equine Encephalitis Tropism |
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Definition
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Term
| Equine Encephalitis Pathogenesis |
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Definition
primary replication at site of bite and regional lymphoid tissue
viremia and systemic spread
secondary replication and viremia
enters CNS and destroys neurons |
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Term
| Equine Encephalitis Mortality |
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Definition
Eastern EE: 90%
Venezualan EE: 50-80%
Western EE: 20-40% |
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Term
| Equine Encephalitis Control |
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Definition
vaccination
vector control
quarantine |
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