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Thyroid gland secretory cells form a what? |
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The follicle surrounds a what? |
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What does a colloid consist of? |
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precursoe protein from which thyroid hormones are formed. |
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What are the major thyroid hormones? |
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Definition
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What are T3 and T4 made from? |
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Definition
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What step is often blocked when hormones are being overproduced? |
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Definition
oxidation to iodine (I2). |
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Because T3 and T4 aren't very water-soluble, they have to be carried through the circulation by what? |
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Definition
thyroxine-binding globulin. |
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What is one of the main effects of thyroid hormones? |
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Definition
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Increased metabolic rate occurs by... |
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Definition
increased O2 consumption and heat production. |
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Increased metabolic rate results in the breakdown of what? |
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Definition
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What are the effects of increased catecholamine action? |
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Definition
increased cardiac output. |
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Thyroid hormones cause the stimulation of what? |
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Thyroid hormones promotes the development of what in children? |
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Definition
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Epinephrine and norepinephrine are examples of what? |
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Definition
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hypothyroidism during growing years. |
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Cretinism symptoms include: |
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Definition
infant-like body proportions, reduced mental development. |
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Causes of hypothyroidism include: |
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Definition
dietary iodine deficiency, radioactive iodine, pituitary & hypothalamic failure. |
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Symptoms of hypothyroidism include: |
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Definition
patient fatigues easily, poor cold tolerance, weight gain, slow pulse, myxedema, carotenemia, and goiters. |
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Definition
accumulation of hyaluronic acid and chondroitin in skin. |
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What does myxedema cause? |
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carotene deposited in the skin. |
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TSH levels are increased, promoting growth. |
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Symptoms of hyperthyroidism include: |
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Definition
increased metabolic rate, weight loss, heat tolerance, irritability, increased heart rate, raise in temperature (sweating), and exophthalmos. |
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What does Grave's disease cause? |
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Definition
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What causes Grave's disease? |
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Definition
body makes antibodies to TSH receptor. |
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What are the antibodies that are made in Grave's disease? |
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Definition
thyroid stimulating immunoglobulin (TSI). |
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What is the function of TSI? |
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Definition
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Increase T3 causes what to decrease? |
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Low thyroid + high TSH causes... |
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High thyroid + low TSH causes... |
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