Term
|
Definition
| Anti- cox --> anti-TXA2 (irreversible) platelet aggregating factor
analgesis |
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|
Term
|
Definition
irreversible Anti-ADP (P2Y)
Clopidegrel activated by CYP2C19
avoid omeprazole
Tica avoid refampin/ketoconazol
cyp2c19 |
|
|
Term
|
Definition
Blocks adenosine uptake --> vasodialtion due to increase of cAMP by blocking PDE
not effective alone |
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|
Term
|
Definition
monoclonal AB to IIB/IIIa
used in urgent cornary ischemia |
|
|
Term
|
Definition
accelerates ATIII
HIT/osteoporosis
antidote is protamine sulfate
monitor APPT |
|
|
Term
|
Definition
| same as heparin just more controllable |
|
|
Term
|
Definition
IV anti-thrombin direct irreversible
used what can used heparin
microvascular surgery to reattach digits |
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|
Term
|
Definition
Anti-Vitamin K epoxide reductase
onset 6-8 hrs, full effect 3 days
may cause skin necrosis or purple toe syndrome
monitor INR/PTT |
|
|
Term
|
Definition
anti-thrombin III that does not involve any cyps liver but prodrug
converted by esterases |
|
|
Term
|
Definition
anti Xa
no antidote
cant be removed via dialysis |
|
|
Term
|
Definition
Anti-fibrin clot
antidote is epsilon amino caproic acid |
|
|
Term
|
Definition
reversible Anti-ADP (P2Y)
Clopidegrel activated by CYP2C19
avoid omeprazole
Tica avoid refampin/ketoconazol
cyp2c19 |
|
|
Term
|
Definition
synthetic heparin-like pentassacharide
best for patients with heparin induced thrombcytopenia |
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|
