Term
|
Definition
Cardiovascular (overall safety green)
(G)Heart Failure: 50-200 mg/day. Maybe contradictory. Studies have shown benefit but others also have not found it benefit. |
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Term
|
Definition
Cardiovascular (likely safe)
Possibly for BP and atherosclerosis
↑ INR in warfarin patients (case reports; ↓ effectiveness of OCs |
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Term
|
Definition
| Cardiovascular (overall safety green) (G)Hypertriglyceridemia: Reduction in TG levels. Cholesterol does not change and HDL increase a little. 1-6 g/day. Sidefects such as belching or halitosis.ardiovascular |
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Term
|
Definition
Cardiovascular (overall safety black)
Blood glucose monitoring
Antiplatelet meds or herbs: possible additive effects
(G)Leg Edema due to chronic venous insufficiency: Reduction of symptoms and leg volume. Safe and effacacious. 150 mg/day. |
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Term
|
Definition
Cardiovascular (overall safety green)
(G) Intermittent Claudication (PAD): Improved symptoms and function. Safe though more research needed for efficacy. 10 mg BID
(B)Hyperlipidemia/hypercholesterolemia: Efficacy only came from trials from one group others cant replicate efficacy. But since its safe its okay. |
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Term
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Definition
Cardiovascular (OS - Green)
Additive activity with used with statins
(G) Hypercholesterolemia: Lowers cholesterol levels (LDL and TG). HDL also increased in one study. 1.2-2.4 g/daily |
|
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Term
|
Definition
Cardiovascular (OS - Green)
(G) Hyperlipidemia: Reduction of total cholesterol. Dose 40-50g/daily |
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Term
|
Definition
Cardiovascular (OS - Green)
(G) Hypercholesterolemia: Lowers cholesterol. 2-10g/day |
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Term
|
Definition
Cardiovascular (OS - Black)
(G) Heart Failure: Improve symptoms and execrcise tolerance. May interact with common HF meds like digoxin (so tell DR. 160-1800 mg/daily |
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Term
|
Definition
Cardiovascular (OS - Green)
(G) Hyperlipidemia: Increase HDL and decrease TG, LDL not defined. 200-600 mcg/day |
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Term
|
Definition
Cardiovascular (OS- Green)
(G) CHF: Improved function (exercise tolerance). Should be under supervision/monitored
(B) Hypertension: Benefits seen whena dded to enalapril/HCTZ therapy. More research needed. Monitor BP carefully. |
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Term
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Definition
CENTRAL NERVOUS SYSTEM
seasonal allergic rhinitis
Asteracea (aster, daisy or sunflower family) allergy
Substrate of CYP34A; avoid with know inducers (i.e. carbamazepine |
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Term
|
Definition
CENTRAL NERVOUS SYSTEM
Migraine prophylaxis and treatment
Asteracea (aster, daisy or sunflower family) allergy |
|
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Term
|
Definition
CENTRAL NERVOUS SYSTEM
Alzheimer's disease |
|
|
Term
| Ginko/Maidenhair tree (CV/CNS) |
|
Definition
CENTRAL NERVOUS SYSTEM
Antiplatelets: possible additive / ↑ effect, Single case report of coma in patient taking low dose trazodone |
|
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Term
|
Definition
CENTRAL NERVOUS SYSTEM
Anxiety disorders
Levadopa: ↓ efficacy; concerns of hepatotoxicity contraindicates use with other meds and supplements that damage liver |
|
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Term
|
Definition
CENTRAL NERVOUS SYSTEM
Sleep disorders in blind
Nifedipine: ↓ absorption and delivery; Fluvoxamine, MAOIs, TCAs: ↑ melatonin effects |
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Term
|
Definition
CENTRAL NERVOUS SYSTEM
CYP34A: ↓ levels and effects (e.g. alprazolam, amitriptyline, nifedipine, simvastatin, theophylline, warfarin); Antidepressants: ↑ risk of serotonin syndromes with nefazadone, sertraline, paroxetine, fluoxetine; ↓ cyclosporine levels case reports of graft rejections; OCs and HRTs: ↓ activity / effectiveness; ↓ serum levels of protease inhibitors and nonnucleoside reverse transcriptase inhibitors |
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Term
|
Definition
CENTRAL NERVOUS SYSTEM
↑ effects with alcohol or other CNS depressants (benzodiazepines) |
|
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Term
|
Definition
CENTRAL NERVOUS SYSTEM
SSRIs, tramadol, diabetic patients: ↑ risk of serotonergic side effects; Carbidoba: ↓ peripheral metabolism |
|
|
Term
| SAMe (CNS and musculoskeletal) |
|
Definition
CENTRAL NERVOUS SYSTEM
Depression |
|
|
Term
| Probiotics (GI/immune modulator) |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
GASTROINTESTINAL / LIVER
Blood glucose monitoring (avoid use)
Antiplatelets: possible additive / ↑ effect at higher doses (> 4gm/d) |
|
|
Term
|
Definition
|
|
Term
|
Definition
GASTROINTESTINAL / LIVER
Ragweed allergy |
|
|
Term
|
Definition
GASTROINTESTINAL / LIVER
↓ absorption of iron salts; premature dissolution of enteric-coated peppermint oil capsules by meds that increase gastric pH (H2 blockers, PPIs) |
|
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Term
|
Definition
GASTROINTESTINAL / LIVER (generally safe)
Constipation, Diarrhea, hemmorhoids, IBS, Weight loss and obseity |
|
|
Term
|
Definition
GASTROINTESTINAL / LIVER (likely safe)
Constipation |
|
|
Term
|
Definition
GASTROINTESTINAL / LIVER
weight control |
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|
Term
|
Definition
|
|
Term
|
Definition
GASTROINTESTINAL / LIVER
Diarrhea |
|
|
Term
|
Definition
ENDOCRINE SYSTEM (might be safe for most)
Blood glucose monitoring
Type 2 diabetes, diabetic neuropathy
↑ bioavailability of valproate |
|
|
Term
|
Definition
ENDOCRINE SYSTEM (OS - Green)
(G) Postprandial Glucose Reduction:Dose 1-3g with meals. |
|
|
Term
|
Definition
|
|
Term
| Dehydroepiandrosterone (DHEA) |
|
Definition
ENDOCRINE SYSTEM (OS - Red)
↑ serum triazolam
(G) Erectile Dysfunction: ED due to HTN or unknown etiology (not including neurological ED)
(B) Sexual Arousal in women:no benefit in young premenopausal women. Self reported in postmenopausal woman benefits. |
|
|
Term
|
Definition
ENDOCRINE SYSTEM (OS - Black)
Avoid using in Immune issue patients (AIDs , RA, Lupus)
(B)Hypoglycemia, Hypocholesterolemia: significant glucose lowering agent but small (though statisticall significant) decrease in lipid. 1gm daily |
|
|
Term
|
Definition
ENDOCRINE SYSTEM (no info about safety)
Diabetes mellitus
Menstrual pain, menorrhagia |
|
|
Term
|
Definition
ENDOCRINE SYSTEM (OS - Black)
(G) Diabetes: significant decrease in fasting blood sugar and HgA1c. (counselled and monitor). 400 mg daily |
|
|
Term
| Evening Primrose Oil (skin/endocrine) |
|
Definition
ENDOCRINE SYSTEM (OS - Green)
(G) Diabetic Neuropathy: reduction of neuropathy symptoms, some with reversal of symptoms. 4gm daily |
|
|
Term
|
Definition
|
|
Term
| Echinacea or Purple Cornflower |
|
Definition
IMMUNE MODULATORS
Avoid using in Immune issue patients (AIDs , RA, Lupus)
Asteracea (aster, daisy or sunflower family) allergy |
|
|
Term
| Probiotics (GI/Immune modulator) |
|
Definition
IMMUNE MODULATORS
Separate dosing of antibiotics or antifungals by 2 or more hours |
|
|
Term
|
Definition
PHYSICAL AND MENTAL PERFORMANCE ENHANCERS
(OS - Green)
(G) Enhance Athletic Performance: Improvement in performance related to high-intensity, repetitive tasks. Seem to occur only in trianed athletes. 15-20g/day then 2-10g day
(B)Strength performance in older adults: 5-15g/day
(B) Hemidialysis-induced leg cramps: reduced leg cramps |
|
|
Term
| Eleuthero (siberian ginseng) |
|
Definition
PHYSICAL AND MENTAL PERFORMANCE ENHANCERS
(OS - Black)
Asteracea (aster, daisy or sunflower family) allergy
Possible false ↑ in serum digoxin (assay dependent); Caffeine ↑ CNS stimulation
(B) Stress Adaptation: improvement in CV response to stress.
(B) Chronic fatigue: No significant improvement over placebo, but statistically significant from baseline with moderate fatigue.
(R) Athletic Performance: No evidence |
|
|
Term
|
Definition
PHYSICAL AND MENTAL PERFORMANCE ENHANCERS
(OS - Green)
Oral hypoglycemics: possible lowered BG levels; Must self-monitor BG
(G) ED: 900mg or 1800 (extract(
(B) Cognition:Improvement in specific areas of cognition (abstract thinking). Long term safety evidence lacking.
(B)Athletic performance: Slight benefit in psychomotor activities, such as reaction time or concentration |
|
|
Term
|
Definition
PHYSICAL AND MENTAL PERFORMANCE ENHANCERS
(OS - Green)
Decongestants: ↑ stimulant effects
(R) weight Loss) no evidence supporting |
|
|
Term
| Pygeum (African Plum Tree) |
|
Definition
KIDNEY, URINARY TRACT & PROSTATE
(OS - Green)
(G): BPH: Decrease in symptoms and improvement in urodynamics. No effect in prostate volume. 100-200 mg/day
Sometimes found in saw palmetto or pumpkin. |
|
|
Term
|
Definition
KIDNEY, URINARY TRACT & PROSTATE
(OS - Green)
UTI prevention: Several studies show effectiveness in prevention. has drug interactions. |
|
|
Term
|
Definition
KIDNEY, URINARY TRACT & PROSTATE
(OS - Green)
(G)BPH: Decrease symptoms and improves flowmetry. No effect on volume. Does not support a recommendation for treatment of mild BPH. Can mask symptoms of prostate cancer |
|
|
Term
|
Definition
KIDNEY, URINARY TRACT & PROSTATE
↑ serum triazolam |
|
|
Term
|
Definition
KIDNEY, URINARY TRACT & PROSTATE
(OS - Green)
(G) - Treatment of Prostate Cancer: May improve prostate cancer-related markers such as PSA. Better Treatment and survival when combined with orchidectomy. |
|
|
Term
|
Definition
KIDNEY, URINARY TRACT & PROSTATE
(OS - Green)
(G) Prostate Cancer prevention: |
|
|
Term
|
Definition
MUSCULOSKELETAL (OS - Green)
Shellfish allergy
Blood glucose monitoring
(G) Osteoarthritis: most highly researched dietary supplement. First line agent for treatment of osteoarthritis. (knee) others might not be as reliable. May take several months. May continue NSAID or APAP. |
|
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Term
|
Definition
MUSCULOSKELETAL (OS - Green)
(G) Osteoarthritis: Benefit to reduce pain and increase function. Fewer new joint erosions. combined with glucosamine. no evidence show that combo is better, also more expensive. |
|
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Term
|
Definition
MUSCULOSKELETAL (OS - Green)
(G) Low Back Pain: recommendation of use for low back pain (reduces NSAID use)
(G) Osteoarthritis: Small studies found improvement in OA. Comparable to diacerhein. More research needed for longterm effect and efficacy. |
|
|
Term
|
Definition
MUSCULOSKELETAL (OS - Green)
(G)Osteoarthritis: gum has been used in ayurvedic medicinal therapies for centuries for inflam disease. can be cautiously recommended. |
|
|
Term
|
Definition
MUSCULOSKELETAL (OS - Black)
(G) Lower Back Pain: Significant benefit in reduction of backpain symptoms. time to imrpovement usualy longer and cost was less.
(B) Osteoarthritis: Can not be recommended for OA ATM.
Number of allergic and AE compare to placebo/conventional treatments. Same risk of gastric ulcer. |
|
|
Term
| Methyl-sulfonyl-methane (MSM) |
|
Definition
MUSCULOSKELETAL (OS - Green)
(B) Osteoarthritis: Benefits were noted and side effects minimal. More research needed to determine extent of efficacy and long term safety. cant be recommended. |
|
|
Term
| S-adenosyl-L-methionine (SAMe) |
|
Definition
|
|
Term
|
Definition
SKIN AND MUCOUS MEMBRANES
(topical OS - Green, Oral - Red)
(G) Psoriasis: Evidence limited but may help reduce psoriatic lesions
(B) Wound Healing: Commonly used in minor wounds and burns but no clinical evidence supports this use. |
|
|
Term
|
Definition
SKIN AND MUCOUS MEMBRANES
Ragweed allergy
Atopic eczema |
|
|
Term
|
Definition
SKIN AND MUCOUS MEMBRANES (OS - Green)
(G) Herpes Labialis (cold Sores): May be effective for shortening duration. No sufficient info to make general recommendation.
(B) Agitation Associated with dementia |
|
|
Term
|
Definition
SKIN AND MUCOUS MEMBRANES (OS - Green)
(G) Acne: Affective for treating acne but less effective than benzoyl peroxide, but less incidence of skin irritation was reported. May be an option if cant tolerate Benzoyl P.
(G) Dandruff: for who cannot tolerate standard treatment.
(G) Athletes foot: not as effective as clotrimazole creams. |
|
|
Term
|
Definition
SKIN AND MUCOUS MEMBRANES (OS - Black)
(B) Atopic Dermatitis: no evidence but one trial had an effect.
(B) periodontitis: Not enough evidence for recommendation |
|
|
Term
|
Definition
| SKIN AND MUCOUS MEMBRANES |
|
|
Term
|
Definition
SKIN AND MUCOUS MEMBRANES (OS - Black)
(G) Oral leukoplakia: Lesions on tongue. Shouldnt be used as monotherapy. |
|
|
Term
|
Definition
|
|
Term
|
Definition
WOMEN’S HEALTH
Premenstrual syndrome |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
EYES
Age-related macular degeneration |
|
|
Term
| Possible interaction with warfarin and or antiplatelets |
|
Definition
| Chondroitin, Coenzyme Q10, Cranberry, Devils claw, evening primrose, fenugreek, feverfew garlic, ginko, ginseng, Green tea, fish oil, kava, phytoestrogens, policosanol, saw palmetto, st johns wart. |
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