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Therapeutics Kerr
Hyperlipidemia
12
Aerospace Engineering
5th Grade
09/01/2009

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Cards

Term
Clinical Athersclerotic Disease that confers high risk for Coronary Heart Disease (CHD)
Definition
  1. MI/ACS
  2. Unstable or Stable Angina
  3. h/o Coronary Procedures: CABG/Angioplasty/Stent
Term
Clinical Athersclerotic Disease that confers high risk for Coronary Heart Disease (CHD) Risk Equivalent
Definition
  1. DM
  2. PVD
  3. Abdominal Aortic Aneurysm (AAA)
  4. Stroke (CAV)/Transiet Ischemic Attack (TIA)
  5. Carotid Artery Disease (stenosis > 50%)
  6. 2+ risk factors with 10 year risk > 20%
Term
Drug Effects on Plasma Lipids: Thiazides
Definition
  • No effect/Increase TC initially
  • Increase TG
  • Increase HDL
  • Effects are transient, however monitor for long-term effects
Term
Drug Effects on Plasma Lipids: Loop Diuretics
Definition
  • Decrease HDL
  • Effects Transiet, however monitor for long-term effects
Term
Drug Effects on Plasma Lipids: Non-Selective Beta Blockers
Definition
  • Increase TGs
  • Decrease HDL
Term
Drug Effects on Plasma Lipids: Selective Beta 1
Definition
  • Increase TGs
  • Decrease HDL
Term
Drug Effects on Plasma Lipids: Alpha agonst/antagonist
Definition
  • No effect/Decrease TC
  • No effect/Decrease TGs
  • No effect/Increase HDL
Term
Drug Effects on Plasma Lipids: Oral Contraceptives
Definition
  • Monophasics increase TC and TGs more than Triphasics
  • Monophasics can either increase or decrease HDL
  • Triphasics increase HDL
Term
Drug Effects on Plasma Lipids: Glucocorticoids
Definition
  • Increase TC
  • Increase TGs
Term
Drug Effects on Plasma Lipids: Ethanol
Definition
  • Increase TGs significantly
  • Increase HDL
Term
Drug Effects on Plasma Lipids: Isotretinoin
Definition
  • Increase TC
  • Increase TGs significantly
  • Decrease HDL
Term
Drug Effects on Plasma Lipids: Cyclosporine
Definition
Increase TC
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