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The Spinal Cord
Neuro
54
Biology
Undergraduate 4
11/30/2011

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Term
What types of neurons are involved in descending pathways
Definition
Upper motor neurons
Term
Motor Cortex
Definition
Planning, initiating and directing voluntary movements
Receives input from the basal ganglia
Term
Brainstem Centers
Definition
Basic movements and postural control
Receives input from the cerebellum
Term
Basal Ganglia
Definition
Gaiting of proper imitation of movement
Term
Cerebellum
Definition
Sensory motor coordinating of ongoing movement
Term
Where does the motor cortex and brainstem centers send info too?
Definition
The local circuit neurons or the motor pools
Term
Local circuit neurons
Definition
lower motor neuron integration
if info sent here first, it will send it to the motor pools
Term
Motor neuron pools
Definition
lower motor neurons
Term
Motor neuron pools send info to where?
Definition
Skeletal muscles
Term
Sensory inputs go to ?
Definition
Local circuit neurons (LMN)
Term
Spinal cord (3 main functions)
Definition
- distributes motor fibersto effector organ
- collects somatosensory info from periphery
- contains some reflex circuits
Term
Dorsal roots
Definition
Info from muscles, skin viscera
Term
Ventral roots
Definition
Outgoing info to muscles, preganglionic sympathetic axons, parasympathetic axons
Term
Gray matter
Definition
cell bodies of neurons
Term
White mater
Definition
ascending/descending fibers
Term
Spinal cord problems: how to transit high volume info at the highest possible speed while ensuring that the system is not exposed to risks
Definition
-Making neuronal axons smaller- miniaturizing is accomplished by myelination
- Concentrating all the transmitting axons into a single fiber that runs in a cushioned tube surrounded by bone
Term
Spinal cord problems: How to organize the system so that information is easily sorted ands the transmission lines are short
Definition
Organize the spinal cord into a matrix of lanes and areas where fibers are responsible fora particular task to travel together
Term
Spinal reflexes
Definition
behaviors that do no involve the brain
Term
Dermatomes
Definition
-segemental organization of spinal cord is most pronounced in regard to the skin
- area innervated by one spinal nerve=one derm

herpes zoster
Term
The amount and shape of both gray and white matter in the spinal cord varies with location
Definition
largest cross sections in cervical and lumbar regions

thoracic and lumbar characterized by lateral horn
Term
nucleus posteromarginalis
Definition
tip of dorsal horn (medium and large neurons)
Term
substancia gelatinosa
Definition
small unmyelinated and thinly unmyelinated neurons
Term
Nucleus proprius
Definition
neurons of various sizes, different pathways
Term
motor cell columns in ventral horn
Definition
LMN
Term
alpha motor neurons
Definition
striated muscle, controls muscles
Term
gamma motor neurons
Definition
muscle spindle fibers
Term
Ascending Pathways (somatosensory)
Definition
carries info from sensory receptors in the skin, viscera, joints and muscles in CNS
Term
First Order Neurons
Definition
-primary afferents whose peripheral endings form the sensory receptors
- transmit the info to the CNS and have cell bodies in dorsal root ganglia
Term
Second Order Neurons
Definition
-located in spinal cord or brainstem and transmit info from the first order neurons to the thalamus
- decussates to synapse in contralateral thalamus
Term
Third order neurons
Definition
These transmit info from one of the sensory nuclei of the thalamus to a sensory region of the cerebral cortex
Term
Fourth order
Definition
-located in sensory regions of the cerebral cortex
-may also synapse on higher order neurons so that hight processing occurs
Term
Asc. Pathways for Pain and Temperature (Anterolateral System)
Definition
includes spinothalamic, spinoreticular, and spinotectal tract
Term
Pathways for tactile information, vibration and kinesthesia
Definition
DCML
Term
Pathways for Somatosensory impulses to cerebellum
Definition
spinocerebellar tracts
Term
Key points in AL system
Definition
- axons decussate in same or adjacent spinal cord segment
- fibers ascend in contralateral in anterolateral funniculus
- project to VPL thalamus and then onto first neuron somatosensory cortex
Term
AL vs DCML

modalities
location in sc
level of decussation
brainstem terminations
cortical terminations
Definition
pain, temp, light touch vs. touch, vibration and proprioception

anterolateral system vs. dorsal column

spinal cord vs medulla

reticular formation vs. VPL nuclei of thalamus
tectum posterior group of thalamus
VPL nuclei of thalamus
posterior group of thalamus

first and second-degree somatosensory cortex and posterior parietal cortex
Term
Spinocerebellar tract
Definition
carries unconscious proprioception to the cerebellum

second order neurons
Term
Descending pathways
Definition
white matter of spinal cord
motor pathways
originate in pre central gyrus
Term
Descending fibers from brain to ventral horn of spinal cord to gray matter =
Definition
UMNS
Term
Descending tracts
Definition
cortico, rubro, vestibulo, reticulo
Term
Cortico and rubro descend where?
Definition
in dorsal lateral aspect of white matter (lateral funicullus)
Term
vestibulo and reticulo descend into?
Definition
ventromedial white matter (ventral funiculus)
Term
lateral vs. ventral corticospinal tract
Definition
90% fibers from motor cortex follow LSCT
10% fibers descend uncrossed in ventral funiculus
Term
Lesions of lateral cortico
Definition
ipsilateral weaknessand spasticity of the affected muscles and below the level of the lesion
Term
Stroke of the brain regions driving the lateral cortico
Definition
result in contralateral weakness and spasticity of the affected muscles and below the level of the lesion
Term
Rubrospinal tract
Definition
-closely related to cortico
-descend together in to lateral funiculus
- uses red nucleus as relay station
- responsible for skilled movements of limb muscles
Term
Vestibulospinal and medial reticulospinal tracts
Definition
-part of ventromedial group in spinal cord
- responsible for decerebrate rigidity
- tonically active when disconnected from cerebellar control
- loss of inhibition of externs and flexor muscles
Term
Vestibulo
Definition
involved with postural movements and gross movements of limb muscles (head balance and turning)
Term
Reticulo
Definition
involved with cardiovascular, respiratory, and other visceromotor functions
Term
ventral horn cells=?=?=?
Definition
primary afferents=sc to skeletal muscles=LMNS
Term
cell groups form read lamina IX
Definition
axial musculature medially in ventral horn
limb musculature laterally in ventral horn
Term
LMNS tell what to do what?
Definition
muscles
Term
UMN lesions
Definition
spastic paralysis
no muscular atrophy
hyper reflexia and clonus
usually babinksi sign
no fibrillations or fasciculations
Term
LMN lesions
Definition
flaccid paralysis
pronounced muscular atrophy
hyporflexia
absence of babinski
fibrillations and fasiciulations
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