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The Peripheral Nervous System
pns
91
Nursing
Graduate
09/16/2014

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Term
THE PNS IS DIVIDED INTO WHAT 3 PARTS?
Definition
THE AUTONOMICNERVUS SYSTEM, SOMATIC NERVOUS SYSTEM, AND ENTERIC NERVOUS SYSTEM
Term
WHAT 2 PARTS IS THE AUTONOMIC NERVOUS SYSTEM DIVIDED INTO?
Definition
SYMPATHETIC NERVOUS SYSTEM AND PARASYMPATHETIC NERVOUS SYSTEM
Term
WHAT 2 AREAS IS CONSIDERED THE CENTRAL NERVOUS SYSTEM?
Definition
AUTONOMIC NERVOUS SYSTEM AND THE SOMATIC NERVOUS SYSTEM
Term
ENDOGENOUS LIGANDS AFFECTING THE NERVOUS SYSTEM ARE CALLED WHAT?
Definition
NEUROTRANSMITTERS
Term
DOES ENDOGENOUS AND EXOGENOUS LIGANDS ALWAYS CAUSE AN EFFECT VIA PERIPHERAL RECEPTORS? CAN THEY CHANGE THE CONCENTRATION OR ACTION OF ENDOGENOUS NEUROTRANSMITTERS?
Definition
NO. YES
Term
WHAT TYPE OF NEURONS IS THE SOMATIC NERVOUS SYSTEM MADE UP OF EXCLUSIVELY AND WHERE DO THEY INNERVATE?
Definition
MOTOR NEURONS THAT INNERVATE THE SKELETAL MUSCLES
Term
WHAT IS THE MAIN NEUROTRANSMITTER OF THE SOMATIC NERVOUS SYSTEM?
Definition
ACETYLCHOLINE
Term
WHAT IS THE MAIN RECEPTOR OF THE SOMATIC NERVOUS SYSTEM?
Definition
NICOTINIC (N). AKA NICOTINIC CHOLINERGIC RECEPTORS. CHOLINERGIC COMES FROM THE TERM ACETYLCHOLINE
Term
WHAT DOES THE ENTERIC NERVOUS SYSTEM DO?
Definition
REGULATES GI TRACT'S MOTILITY AND SECRETION.
Term
WHERE IS THE ENTERIC NERVOUS SYSTEM'S INNERVATION FROM? CAN THE ENS FUNCTION WITHOUT THE ANS?
Definition
AUTONOMIC NERVES.. YES, THE ENS CAN FUNCTION WITHOUT THE ANS
Term
WHICH TYPE OF STIMULATION ACTIVATES THE ENS? WHAT TYPE OF STIUMULATION INHIVITS THE ENS?
Definition
PARASYMPATHETIC, SYMPATHETIC
Term
WHAT ARE THE NEUROTRANSMITTERS ASSOCIATED WITH ENTERIC NERVOUS SYSTEM?
Definition
NEUROPEPTIDE Y, VASOACTIVE INTESTINAL POLYPEPTIDE (VIP), ENKEPHALIN, SUBSTANCE p, SEROTONIN, ATP, AND NITRIC OXIDE AMONG OTHERS
Term
WHAT SYSTEM ARE WE PRIMARILY ALTERING WITH ANESTHESIA?
Definition
AUTONOMIC NERVOUS SYSTEM
Term
THE INVOLUNTARY REGULATION OF THE ANS ARE IN WHAT AREAS?
Definition
CARDIAC MUSCLE, SMOOTH MUSCLE, VISCERAL REFLEXES, AND GLANDULAR FUNCTIONS
Term
WHAT TPE OF NEURONS DOES BOTH THE SNS AND PNS DIVISIONS CONTAIN.
Definition
BOTH DIVISIONS CONTAIN A PREGANGLIONIC AND POSTGANGLIONIC NEURONS.
Term
WHAT IS A GANGLION?
Definition
IS A MASS OF NERVE CELL BODIES
Term
WHERE DOES PREGANGLIONIC NEURONS ORIGINATE AND TERMINATE AT?
Definition
NEURONS ORIGINATE IN THE BRAINSTEM AND SPINAL CORD AND TERMINATE AT AUTONOMIC GANGLIA.
Term
WHAT ARE AUTONOMIC GANGLIA?
Definition
SYNAPSE POINTS BETWEEN PRE- AND POSTGANGLIONIC NEURONS.
Term
WHERE DOES POSTGANGLIONIC NEURONS HAVE THEIR CELL BODIES AT AND WHERE DO THEY TERMINATE?
Definition
POSTGANGLIONIC NEURONS HAVE THEIR CELL BODIES AT THE AUTONOMIC GANGLIA AND TERMINATE AT EFFECTOR ORGANS
Term
WHERE DOES THE SNS NERVES ARISE FROM?
Definition
THE THORACIC AND LUMBAR SPINAL CORD. AKA THORACOLUMBAR SYSTEM. T1-L3
Term
ARE THE SNS PREGANGLIONIC AND POSTGANGLIONIC FIBERS SHORT OR LONG?
Definition
SHORT PREGANGLIONIC AND LONG POSTGANGLIONIC FIBERS
Term
WHAT DOES THE SNS PREGANGLIONIC FIBERS CARRY?
Definition
IMPULSES TO ONE OF MANY SYMPATHETIC GANGLIA.
Term
WHAT IS THE PARAVERTEBRAL CHAIN ALSO KNOWN AS?
Definition
SYMPATHETIC CHAIN GANGLIA
Term
DOES NERVE FIBERS SYNAPSE IN THE SYMPATHETIC CHAIN GANGLIA?
Definition
SOME NER FIBERS SYNAPSE IN THE CHAIN, WHILE OTHERS PASS THROUGH AND SYNAPSE IN GANGLIA SLIGHTLY MORE DISTAL FROM THE CORD.
Term
THE CEPHALAD PORTION IS MADE UP OF 3 DISTINCT GANGLIA. WHAT ARE THEY?
Definition
SUPERIOR CERVICAL GANGLION, MIDDLE CERVICAL GANGLION, AND LOWER CERVICAL GANGLION AKA (STELLATE GANGLION)
Term
WHAT DOES THE SUPERIOR CERVICAL GANGLION DO?
Definition
PROVIDES INNERVATION TO THE PUPIL, SALIVARY GLANDS, LACRIMAL GLANDS, AND BLOOD VESSELS AND SWEAT GLANDS OF THE HEAD AND NECK.
Term
WHAT DOES THE MIDDLE CERVICAL GANGLION DO?
Definition
PROVIDES INNERVATION TO THE HEART AND LUNGS.
Term
WHAT DOES THE LOWER CERVICAL GANGLION AKA STELLATE GANGLION DO?
Definition
COMBINES LOWER CERVICAL AND UPPER THORACIC NERVES. PROVIDES INNERVATION TO HEAD, NECK AND ARM (BLOOD VESSELS, SWEAT GLANDS), THE HEART AND LUNGS
Term
WHAT ARE THE 2 PREVERTEBRAL GANGLIA?
Definition
CELIAC GANGLION AND SUPERIOR AND INFERIOR MESENTERIC GANGLIA.
Term
WHERE ARE THE PREVERTEBRAL GANGLIA ARRANGED AT?
Definition
ANTERIOR TO THE AORTA
Term
WHAT IS UNIQUE ABOUT THE PREVERTEBRAL VS PARAVERTEBRAL CHAIN?
Definition
IN COMPARISON TO THE NEURONS THAT SYNAPSE IN THE PARAVERTEBRAL CHAIN, THESE NEURONS HAVE A LONGER PREGANGLIONIC SEGMENT.
Term
WHERE DOES THE CELIAC GANGLION RECEIVE INNERVATION?
Definition
FROM THE SPLANCHNIC NERVE (THORACIC ORIGIN)
Term
WHAT DOES THE POSTSYNAPTIC CELIAC GANGLION NEURONS INNERVATE?
Definition
STOMACH, LIVER, SPLEEN, SMALL INTESTINES, PANCREAS, KIDNEY AND ABDOMINAL BLOOD VESSELS
Term
WHAT PART OF THE SPINE DOES THE SUPERIOR AND INFERIOR MESENTERIC GANGLIA RECEIVE SIGNALS FROM?
Definition
THE LUMBAR PORTION OF THE SPINE
Term
WHERE DOES THE SUPERIOR AND INFERIOR MESENTERIC GANGLIA INNERVATE?
Definition
THE LARGE INTESTINES, RECTYM, GENITALS, BLADDER, AND LOWER EXTREMITIY BLOOD VESSELS
Term
WHAT IS THE NEUROTRANSMITTER THAT IS EXCRETED AT NERVE TERMINAL OF PREGANGLIONIC NEURONS?
Definition
ACH
Term
WHAT TYPE OF RECEPTORS ARE PRESENT AT THE SYNPASE GANGLIA?
Definition
NICOTINIC RECEPTORS
Term
WHERE DOES THE POSTGANGLIONIC FIBERS BEGIN AND END AT?
Definition
POSTGANGLIONIC FIBERS BEGIN AT THE GANGLION AND TRAVEL THE DISTANCE TO THE INNERVATED ORGAN
Term
WHAT TYPE OF POSTGANGLIONIC FIBER INNERVATE THE MAJORITY OF THE ORGANS AND VESSELS IN OUR BODY?
Definition
SYMPATHETIC POSTGANGLIONIC FIBERS
Term
WHAT IS THE RATIO OF PREGANGLIONIC TO POSTGANGLIONIC NEURONS?
Definition
1:20. DIFFUSE REACTION SOCCUR AFTER SYMPATHETIC STIMULATION
Term
WHAT IS THE NEUROTRANSMITTER AT THE NERVE TERMINAL FOR POSTGANGLIONIC FIBERS?
Definition
NOREPINEPHRINE
Term
WHAT ARE THE RECEPTORS FOR POSTGANGLIONIC FIBERS?
Definition
ADRENERGIC RECEPTORS. ADRENERGIC COMES FROM THE WORK ADRENALINE, SYNONYMOUS WITH EPINEPHRINE... NORADRENERGIC REFERS TO NORADRENALINE OR NOREPINEPHRINE...ADRENERGIC RECEPTOS INCLUDE ALPHA, BETA, AND DA (DOPAMINERGIC) RECEPTORS
Term
A SWEAT GLAND IS AN EXCEPTION TO THE POSTGANGLIONIC FIBER. WHAT DOES THE POSTGANGLIONIC NERVE FIBERS RELEASE AND WHAT ARE THE RECEPTORS?
Definition
ACH, MUSCARINIC CHOLINERGIC RECEPTORS (M)
Term
DOES THE SYMPATHETIC NERVES THAT INNERVATE THE ADRENAL MEDULA SYNAPSE IN A GANGLION?
Definition
NO. THE PREGANGLIONIC NERVE FIBER CARRIES THE IMPULSE DIRECTLY TO THE ADRENAL GLAND
Term
ACH IS THE NEUROTRANSMITTER RELEASED TO THE WHAT CELL IN THE ADRENAL MEDULLA?
Definition
CROMAFFIN
Term
ONCE ACH BIND TO THE CROMAFFIN CELLS IN THE ADRENAL MEDULLA WHAT IS RELEASED INTO THE SYSTEMIC CIRCULATION?
Definition
EPINEPHRINE AND NOREPINEPHRINE
Term
THE RELEASE OF CATECHOLAMINES GREATLY FAVORS WHAT?
Definition
80% EPI AND 20% NOREPI. THE ADRENAL MEDULLA IS THE ONLY PLACE THAT EPI IS RELEASED
Term
THE VASCULAR BEDS OF SKELETEAL MUSCLES HAVE SOME SYMPATHETIC INNERVATION WHICH CAUSES VASODILATION. WHAT ARE THE RECEPTORS?
Definition
NICOTINIC CHOLINERGIC RECEPTORS
Term
DOES THE PARASYMPATHETIC NERVOUS SYSTEM PERFORM REST AND DIGEST?
Definition
YES. SALIVATION, LACRIMATION, URINATION, DEFACATION
Term
NERVES OF THE PARASYMPATHETHIC NERVOUS SYSTEM ARISE FROM WHICH CRANIAL NERVES?
Definition
3,7,9,10 AND SACRAL PORTION OF THE SPINAL CORD
Term
WHAT IS THE PARASYMPATHETHIC NERVOUS SYSTEM ALSO KNOWN AS?
Definition
CRANIOSACRAL SYSTEM
Term
ARE THE PARASYMPATHETHIC NERVOUS SYSTEM PREGANGLIONIC AND POSTGANGLIONIC NEURINS SHORT OR LONG?
Definition
OPPOSITE OF SNS. LONG PREGANGLIONIC AND SHORT POSTGANGLIONIC
Term
WHERE DOES THE GANGLIA POSITIONED AT IN THE PNS?
Definition
THEY LIE IN OR VERY NEAR TO THE EFFECTOR ORGAN
Term
WHAT DOES CN 7 DO FROM THE PARASYMPATHETHIC NERVOUS SYSTEM?
Definition
SUBMAXILLARY AND SUBLINGUAL GLAND SALIVATION. LACRIMAL GLAND TEAR PRODUCTION
Term
WHAT DOES THE PARASYMPATHETHIC NERVOUS SYSTEM DO TO CN9.
Definition
PAROTID GLAND SALIVATION
Term
WHAT IS THE PERCENTAGE OF CN 10 THAT ACCOUNTS FOR THE PNS ACTIVITY? WHAT ORGANS DO THEY ACCOUNT FOR?
Definition
75. MAJOR ORGANS IN CHEST AND ABDOMEN AND GI SYSTEM DOWN TO PROXIMAL COLON
Term
WHAT TYPES OF NERVES FROM THE PNS INNERVATE THE REMAINDER OF THE COLON, BLADDER, AND GENITALS.
Definition
THE SACRAL NERVES
Term
FOR THE PNS WHAT IS THE NEUROTRANSMITTER RELEASED AT PREGANGLIONIC NERVE TERMINAL?
Definition
ACH
Term
WHAT IS THE RECEPTOR AT THE AUTONOMIC GANGLIAM OF THE PNS?
Definition
NICOTINIC
Term
WHAT IS THE NEUROTRANSMITTER THAT IS RELEASED AT POSTGAGNGLIONIC NERVE TERMINAL OF THE PNS?
Definition
ACH
Term
WHAT IS THE RECEPTOR AT THE POSTGANGLIONIC NERVE TERMINAL (EFFECTOR ORGAN) OF THE PNS?
Definition
MUSCARINIC
Term
WHAT IS THE RATIO OF PREGANGLIONIC TO POSTGANGLIONIC NEURONS IN THE PNS?
Definition
1:1 OR 1:3. THIS ALLOS FOR MORE PRECISE OR DISCRETE RESPONSE TO STIMULATION THAT SEEN WITH SNS.
Term
WHAT IS ACH SYNTHESIZED FROM, WHERE, AND BY WHAT?
Definition
ACH IS SYNTHESIZED FROM CHOLINE AND ACETATE N THE CYTOPLASM OF THE NEURON BY ACTEYLTRANSFERASE
Term
WHAT IS THE RATE LIMITING STEP IN ACH SYNTHESIS?
Definition
THE AVAILABILITY OF CHOLINE
Term
WHERE IS ACH STORED AT WHILE IT AWAIT SON ACTION POTENTIAL?
Definition
IN THE VESICLES OF THE NEURON
Term
WHAT HAPPENS WHEN THE NERVE IS STIMULATED-WHAT DOES CALCIUM DO?
Definition
THE ACTION POTENTIAL CAUSES CALCIUM TO ENTER THE NEURON, INDUCING EXOCYTOSIS OF THE NEUROTRANSMITTER-FILLED VESICLES.
Term
WHAT IS THE GOAL OF THE ACH AFTER IT IS RELEASED BY EXOCYTOSIS?
Definition
THE VESICLES RELEASE THE ACH INTO THE SYNAPSE OF THE NEURON FOR IT TO STIMULATE THE POST SYNAPTIC CHOLINERGIC RECEPTORS
Term
IF THE POST RECEPTORS AFTER THE SYNAPSE ARE IN THE SYMPATHETIC OR PARASYMPATHETIC GANGLIA WHAT IS GOING TO HAPPEN?
Definition
THEY CAUSE THE PROPAGATION OF THE IMPULSE DOWN THE POSTGANGLIONIC FIBER
Term
IN THE SOMATIC NERVOUS SYSTEM WHAT NEUROTRANSMITTER STIMULATES WHAT RECEPTORS ON SKELETAL MUSCLES?
Definition
THE SOMATIC NERVOUS SYSTEM THE ACH STIMULATE THE NICOTINIC RECEPTORS ON SKELETAL MUSCLE
Term
THE SYNAPTIC ACH CAN ALSO STIMULATE RECEPTORS ON WHAT SIDE OF THE NEURON? WHAT DOES THIS DO AND WHAT IS IT CALLED?
Definition
THE PRESYNAPTIC SIDE. THIS IN TURN STIMULATES THE RELEASE OF MORE ACH (POSITIVE FEEDBACK).
Term
AFTER THE POSTSYNAPTICE RECEPTOR IS STIMULATED, THE ACH IS RAPIDLY HYDROLYZED BY WHAT, BACK TO WHAT?
Definition
ACETYLCHOLINESTERASE BACK TO CHOLINE AND ACETATE
Term
WHAT HAPPENS AFTER ACH IS BROKEN DOWN IN THE POSTSYNAPTIC RECEPTOR?
Definition
THE CHOLINE IS TRANSPORTED BACK IN TO THE NERVE TERMINAL AND RECYCLES BACK INTO ACH.
Term
WHAT IS A STRUCTURE OF A CATECHOLAMINE?
Definition
A CATECHOL NUCLEUS (A BENZENE RING WITH 2 ADJACENT HYDROXYL GROUPS) AND AN AMINE-CONTAINING SIDE CHAINE
Term
WHERE DOES CATECHOLAMEIN SYNTHESIS TAKE PLACE AT?
Definition
IN NERVE TERMINALS AND IN CROMAFFIN CELLS
Term
TYROSINE IS TRANSPORTED INTO THE NERVE TERMINAL AND CONVERTED BY THE ENZYME ______ INTO ______.
Definition
TYROSINE HYDOXYLASE INTO DIHYDROXYPENYLALANINE (DOPA)
Term
WHAT IS THE RATE LIMITING ENZYME FOR CATECHOLAMEIN SYNTHESIS?
Definition
TYROSINE HYDROXYLASE. THEREFORE, THIS IS THE RATE LIMITING STEP
Term
IN THE CYTOPLASM OF THE NEURON WHAT IS DOPA CONVERTED TO AND BY WHAT ENZYNME?
Definition
DOPA IS CONVERTED TO DOPAMINE BY THE ENZYME DOPA DECARBOXYLASE
Term
WHAT HAPPENS AFTER DOPA IS CONVERTED TO DOPAMINE?
Definition
IT IS TRANSPORTED INTO THE SYNAPTIC VESICLES WHERE IT IS CONVERTED TO NOREPINEPHRINE BY THE ENZYME DOPAMINE-BETA-HYDROXYLASE
Term
IN THE ADRENAL MEDULLA THE NOREPI IS CONVERTED TO WHAT BY WHAT?
Definition
EPI BY PHENYLETHANOLAMINE N-METHYTRANSFERASE (PNMT)
Term
PNMT CONCENTRATION IS HIGHYL DEPENDENT ON AN ADEQUATE AMOUT OF WHAT BEING DELIVERD INTO THE ADRENA MEDULLA?
Definition
CORTISOL
Term
NEUROTRANSMITTER RELEASE IS MEDIATED IN THE SAME WAY AS ACH RELEASE WHICH IS HOW?
Definition
BY CALCIUM-MEDIATED EXOCYTOSIS.
Term
PRESYNAPTIC ADRENERGIC RECEPTOR STIMULATION LEADS TO THE INHIBITION OF WHAT?
Definition
NOREPI RELEASE (NEGATIVE FEEDBACK)
Term
AS A CATECHOLAMINE DIFFUES AWAY FROM THE RECEPTOR, IT IS REMOVED FROM THE SYNAPTIC CLEFT BY HOW MANY MECHANISMS?
Definition
3
Term
ONE WAY A CATECHOLAMEIN DIFFUSES AWAY FROM THE RECEPTOR IS BY
Definition
REUPTAKE OF THE CATECHOLAMINE INTO THE PRESYNAPTIC NEURON. THIS IS BY FAR THE MOST IMPORTANT DETERMINANT IN THE TERMINATION OF CATECHOLAMEIN EFFECT
Term
ANOTHER WAY A CATECHOLAMEIN DIFFUSES AWAY FROM THE RECEPTORS IS BY
Definition
DIFFUSION OUT OF THE SYNAPTIC CLEFT
Term
THE 3RD WAY A CATECHOLAMINE DIFFUSES AWAY FROM THE RECEPTOR IS BY
Definition
METABOLISM OF THE CATECHOLAMINE TO AN INACTIVE METABOLITE
Term
WHAT 2 ENZYMES TAKE PART IN CATECHOLAMINE METABOLISM?
Definition
MONOAMINE OXIDASE (MAO) AND CATECHOL-O-METHYLTRANSFERASE (COMT)
Term
WHERE IS MAO PRESENT AT?
Definition
MITOCHONDRIA OF NEURONS
Term
WHAT DOES MAO-A METABOLIZE?
Definition
SEROTONIN, NOREPI, AND DOPAMINE, AS WELL AS DETOXIFIES CHEESE AND WINE
Term
WHAT DOES MAO-B METABOLIZE?
Definition
IS MORE SELECTIVE FOR DOPAMINE
Term
EPI AND NOREPI ARE METABOLIZED BY MAO AND COMT INTO SEVERAL INACTIVE METABOLITES WHICH ARE EXCRETED IN THE URINE AS
Definition
METANEPHRINE, NORMETANEPHRINE AND VANILLYLMANDELIC ACID (VMA)
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