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The List
The List
6
Pharmacology
Graduate
08/20/2011

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Cards

Term
How does cimetidine (TAGAMET) work?
Definition
Competitively block H2 receptors on parietal cells, reducing gastric acid secretion.
Term
How does cimetidine interact with CYP enzymes
Definition
3A4 enzyme inhibitor
Term
Cimetidine may decrease absorption of which drugs?
Definition
AZOLEs: itraconazole, ketoconazole; AVIRs: indinavir, atazanavir; Tyrosine kinase inhibitors: dasatinib, gefitinib, erlotinib
Term
What are the practice points for cimetidine?
Definition
Consider using a different H2 antagonist.
Term
What are the side effects of long term corticosteroid use?
Definition
weight gain, infection, GI ulcers/bleeding, osteoporosis, weight gain, weight gain, insomnia, oedema/hypertension, steroidal withdrawal syndrome: fatigue, muscle stiffness/pain, joint pain, fever.
Term
what are the symptoms of steroid withdrawal syndrome?
Definition
fatigue, muscle stiffness/pain, joint pain, fever.
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