Term
| pyruvate dehydrogenase complex (pdh) |
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Definition
pyruvate is converted to acetyl-CoA. made of three enzymes and 5 coenzymes. |
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Term
| the three enzymes involved in the pyruvate dehydrogenase complex |
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Definition
pyruvate dehydrogenase dihydrolypoyl transacetylase dihydrolypoyl dehydrogenase |
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Term
| how does the PDH complex work? |
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Definition
| substrate channeling and intermediates never leave the enzyme surface |
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Term
| 5 coenzymes involved in the pyruvate dehdrogenase complex |
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Definition
thiamin pyrophosphate(tpp) nicotinamide adenine dinucleotide(NAD) FAD CoA Lipoate/lipoic acid |
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Term
| enzyme that adds acetyl CoA to oxaloacetate to form citrate |
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Definition
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Term
| enzyme that changes citrate to isocitrate |
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Definition
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Term
| enzyme that change isocitrate to alpha-ketoglutarate |
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Definition
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Term
| enzyme that changes alpha ketoglutarate to succinyl-CoA |
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Definition
| alpha ketoglutarate dehydrogenase complex |
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Term
| enzyme that changes succinyl-CoA to succinate |
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Definition
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Term
| enzyme that changes succinate to fumarate |
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Definition
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Term
| enzyme that changes fumarate to malate |
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Definition
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Term
| enzyme that change malate to oxaloacetate |
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Definition
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Term
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Definition
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Term
| three enzymes that reduce NAD to NADH |
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Definition
isocitrate dehydrogenase alpha ketoglutarate DH complex malate dehydrogenase |
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Term
| enzyme that reduce FAD to FADH2 |
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Definition
| succinate dehydrogenase(succinate to fumarate) |
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Term
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Definition
| succinyl-CoA to succinate(succinyl-CoA synthetase) |
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Term
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Definition
competitive inhibitor of succinate dehydrogenase the enzyme can't bind to succinate to form fumarate |
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Term
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Definition
acetyl-CoA to citrate Isocitrate to alpha ketoglutarate alpha ketoglutarate to succinyl-CoA they are regulators of the TCA cycle |
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Term
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Definition
pyruvate to oaa pep to oaa pyruvate to malate |
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Term
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Definition
binds to CO2 and transports it to oxaloacetate bound to pyruvate carboxylase |
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Term
inhibitors of the TCA cycle |
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Definition
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Term
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Definition
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Term
| thermodynamics of the TCA cycle |
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Definition
under cellular conditions, most rxns are in equilibrium |
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