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The Integumentary System
n/a
24
Anatomy
Undergraduate 2
03/03/2009

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Term
Epidermis
Definition
layer of skin made up of stratified squamous epithelium
Term
Dermis
Definition
layer of skin made up of areolar and dense irregular connective tissue.
Term
Hypodermis
Definition
a subcutaneous layer, filled mostly with fat; this fat serves as insulation as well as fuel storage.
Term
Stratum basale
Definition
layer of the epidermis which constantly undergoes mitosis to replace cells exfoliated from the skin's surface.
Term
Stratum spinosum
Definition
layer of the epidermis which consists of cells attached to one another by fibrous desmosomes which enable tje skin to be pulled and stretched without the cells pulling apart.
Term
Keratinized
Definition
skin cells die and become hard, flattened cells completely filled with keratin and keratohyaline.
Term
Cornified outer layer
Definition
When this layer of the epidermis thickens as a result of constant pressure it produces "corns" and calluses seen on the feet and hands.
Term
Thick skin
Definition
has the presence of the stratum lucidium.
Term
Thin Skin
Definition
there is NO stratum lucidum and there may be fewer layers in the stratum spinosum.
Term
Melanin
Definition
varies in colors among the races and helps protect the cells from UV radiation.
Term
Cancer
Definition
this occurs when genetic change result in turning on, or not turning off, genes which regulate normal cell division and tissue growth.
Term
Squamous cell carcinoma
Definition
this type of cancer occurs in the keratinocytes of the intermediate or transitional layers of the epidermis.
Term
Apoptosis
Definition
this results in the protective layer of flattened, dead cells found in the outer cornified layer. acceleration of this mechanism is an important response of these cells to sun exposure. If this mechanism fails then these cells can become abnormal and produce cancer.
Term
Basal Cell Carcinoma
Definition
this cancer is the result of an abnormal growth of the basal cells. These cells are normally protected from UV exposure by the melanin secreted by nearby melanocytes. This form of cancer can usually be successfully treated surgically of caught in time.
Term
Melanoma
Definition
This is a cancer of the melanocytes which is the most dangerous because it often metastasizes to other tissues and organs.
Term
Sebum
Definition
hairs are bathed in this oily substance which helps the skin to remain moist and resist water loss.
Term
Lanolin
Definition
this is used in many cosmetics and is sebum from sheep.
Term
Meissner's Corpuscle
Definition
free nerve endings which respond to change in shape of the capsule by producing an action potential (nerve signal); they are fast adapting, which means they stop responding to a continuous stimulus. That is why you don't notice your clothes touching your body.
Term
Free Nerve Endings
Definition
these nerves project into the dermis just below the epidermis, providing sensations of pain when they are disrupted.
Term
Eccrine glands
Definition
secrete watery liquid for thermoregulation; are extensive on skin.
Term
Apocrine glands
Definition
found in groin and axilla (arm pit), secret more viscous fluid containing pheromones, believed important for sexual arousal.
Term
Sudoriferous gland and duct
Definition
sweat gland; two types eccrine and apocrine
Term
Arrector Pili muscle
Definition
these muscles are found in the dermis and are attached at one end to the hair root, and at the other end to the basement membrane of the epidermis. They are controlled by the autonomic nervous system and are responsible for raising the hair roots to produce "goose bumps" during thermoregulation and stress situations.
Term
Granulation Tissue
Definition
blood vessels invade the clot and the budding capillaries.
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