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The Endocrine System
Hormones and Structures
102
Veterinary Medicine
Undergraduate 2
04/22/2013

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Term
Which system gives rapid control?
Definition
The nervous system
Term
Which system regulates long term chances?
Definition
The endocrine system
Term
What do both the nervous and endocrine system produce?
Definition
Chemical transmitters
Term
What are the two types of chemical transmitter?
Definition
Neurotransmitter
Hormones
Term
What produces neurotransmitters?
Definition
Neurons
Term
What produces hormones?
Definition
Endocrine Glandular Cells
Modified Neurons
Term
What are the differences between neurotransmitters and hormones?
Definition
Neurotransmitters only travel short distances and produce their effects on the muscles and glands while hormones travel ling distances in the blood effect all tissues and organs
Term
Which gland is known as the master gland?
Definition
The pituitary gland
Term
Which part of the brain manages the endocrine system?
Definition
Hypothalamus
Term
Which part of the brain is the hypothalamus found?
Definition
Diencephalon
Term
What acts do they hypothalamus preform which are vital for life?
Definition
regulates thirst, sleep and temperature
monitors levels of hormones and other chemicals in the blood
controls the functioning of the anterior pituitary gland
Produces ADH and Oxytocin which are stored in the posterior pituitary gland
Term
What is homeostasis?
Definition
Maintenance of the body's internal environment
Term
Define: Exocrine Gland
Definition
Gland whose secretions pass in a system of ducts which lead to the exterior of the body
Term
Some examples of an exocrine gland?
Definition
Sweat Gland
Salivary Gland
Mammary Gland
Stomach
Liver
Pancreas
Term
Define: Endocrine Gland
Definition
A gland that secretes hormones into the blood stream
Term
Some examples of an endocrine gland?
Definition
Pituitary Gland
Pancreas
Ovaries
Testes
Thyroid Gland
Adrenal Glands
Term
Define: Hormone
Definition
A substance that is made in one part of the body but affects another
Term
Some examples of Hormones
Definition
Insulin
Thyroxin
Prolactin
Oxytocin
Oestrogen
Testosterone
Term
Define: Releasing Hormone
Definition
A hormone whose main purpose is to control the release of another hormone
Term
Some examples of releasing hormones...
Definition
Thytotropin Releasing Hormone
Corticotropin Releasing Hormone
Gonadotropin Releasing Hormone
Growth Hormone Releasing Hormone
Term
Define: Inhibiting Hormone
Definition
A hormone that stops the secretion of another hormone
Term
Examples of inhibiting hormones...
Definition
Somatostatin
Dopamine
Term
What are the five ways hormones can be categorised?
Definition
Regulate internal chemical composition
Respond to changes in environment
Help integrate growth and development
Contribute to reproduction
Help regulate metabolism and energy balance
Term
Define: Permissiveness
Definition
When a hormone cannot exert its full effects without the presence of another hormone
Term
Define: Synergism
Definition
When two or more hormones produce the same effects in a target cell and their results are amplified
Term
Define: Antagonism
Definition
When a hormone opposes or reverses the effect of another hormone
Term
What is the process of hormonal signalling?
Definition
Biosynthesis of a particular hormone in a particular tissue
Storage and Secretion of the hormone
Transport of the hormone to the target cells
Recognition of the hormone by associated cell membrane or intracellular receptor protein
Relay and Amplification of the received hormonal signal
Degradation of the hormone
Term
What is the most common method of control in regards to hormones?
Definition
Negative Feedback Loops
Term
What is a Negative Feedback Loop?
Definition
Where production of a hormone is inhibited by a large circulating volumes of the same hormone in the circulation
Term
What do negative feedback loops ensure?
Definition
Optimum concentration of hormone is maintained in the body
Term
What are the major endocrine glands?
Definition
Pituitary Gland
Thyroid Gland
Parathyroid Gland
Pancreas
Ovary
Testes
Adrenal Glands
Pineal Gland
Term
Where is the pituitary situated?
Definition
in the pituitary fossa above the hard palate
Term
What is the technical term for the anterior pituitary gland?
Definition
Adenohypophysis
Term
What is the technical term for the posterior pituitary gland?
Definition
Neurohypophysis
Term
The anterior pituitary gland is a region of glandular tissue, true or false?
Definition
True
Term
The posterior pituitary gland is a outgrowth of the hypothalamus and therefore nervous in origin, true or false?
Definition
True
Term
What are the types of hormones which are produced by anterior pituitary gland?
Definition
Trophic Hormones which stimulate the activity of their respective endocrine glands
Term
Where is THYROID STIMULATING HORMONE secreted from?
Definition
Anterior Pituitary Gland
Term
What are the functions of the TSH?
Definition
Promotes normal development and activity of the thyroid gland and stimulates the thyroid gland to produce its own hormones
Term
What stimulates the release of TSH?
Definition
Hypothalamic Thyrotropin-Releasing Hormone
Term
Where is ADRENOCORTICOTROPHIC HORMONE (ACTH) secreted from?
Definition
Anterior Pituitary Gland
Term
What are the functions of ACTH?
Definition
Regulates growth of the adrenal cortex
Stimulates the adrenal cortex to produce its own hormones
Term
What stimulates the release of ACTH?
Definition
Corticotrophin-Releasing Hormone
Term
Where is FOLLICLE STIMULATING HORMONE (FSH) released from?
Definition
Anterior Pituitary Gland
Term
What are the functions of FSH?
Definition
Regulates the development, growth and maturation of the reproductive process
Initiates changes in the ovaries that result in oogenesis
stimulates oestrogen secretion creating sexual behaviour
stimulates spermatogenesis in males
Term
What hormone stimulates the secretion of FSH?
Definition
Gonadotrophin Releasing Hormone
Term
Where is LUTEINISING HORMONE released from?
Definition
Anterior Pituitary Hormone
Term
What are the functions of LH?
Definition
when the levels of LH increase ovulation occurs and the corpus luteum develops
Term
What causes LH to be secreted?
Definition
When maturing follicle secretes oestrogens, FSH is inhibited and LH is produced
Term
Where is SOMATOTROPHIN released from?
Definition
Anterior Pituitary Gland
Term
What is the other name for Somatotrophin?
Definition
Growth Hormone
Term
Where is PROLACTIN released from?
Definition
Anterior Pituitary Hormone
Term
What is the function of Prolactin?
Definition
Stimulates milk production
Term
How is the production of Prolactin increased?
Definition
By a positive feedback loop
Term
Where is Antidiuretic Hormone (ADH) released from?
Definition
Posterior Pituitary Gland
Term
What are the functions of ADH?
Definition
stimulates the kidneys to reabsorb and conserve water resulting in concentrated u+ and raised blood pressure
Term
Where is Oxytocin released from?
Definition
Posterior Pituitary Gland
Term
What is the function of Oxytocin?
Definition
stimulates contraction of uterine muscles
Term
What triggers the release of Oxytocin ?
Definition
Pressure on the cervix during parturition
Term
How is Oxytocin release regulated?
Definition
Positive feedback mechanism
Term
Where is the Thyroid Gland located?
Definition
In the throat close to larynx
Term
What is the tissue called that connects the lobes of the Thyroid Gland?
Definition
Isthmus
Term
What are within the Thyroid Gland which produce the thyroid hormones?
Definition
Follicles
Term
What three hormones are produced by the thyroid gland?
Definition
Tri-iodothronine (T3)
Thyroxine (T4)
Calcitonin
Term
What is the function of T3?
Definition
Levels of this in practice are clinically important. The main function is that it exerts its effects on the body's metabolism
Term
What stimulates the production of the thyroid hormones?
Definition
Thyroid Stimulating Hormone
Term
What cells produce CALCITONIN?
Definition
C cells found inbetween the thyroid follicles
Term
What is the function of the Calcitonin?
Definition
Regulates calcium levels in the blood by encouraging uptake of calcium by the bones when levels are increased beyond normal
Term
What is Calcitonin secreted in response to?
Definition
High Blood Calcium Levels
Term
What are the main actions of Calcitonin?
Definition
Stops the uptake of calcium from the GIT
Stops demineralisation of bone
Stops Kidneys picking up Phosphorus
Increases the reabsorption of Calcium by Kidneys
Term
Where are the Parathyroid glands found?
Definition
On either side of the thyroid gland
Term
When is parathyroid hormone secreted?
Definition
When there are low levels of calcium in the blood
Term
What are the main actions of Parathyroid hormone?
Definition
Increases movement of calcium from the bones
Increases reabsorption of calcium by the kidneys and absorption by the GIT
Increases excretion of Phosphorus
Increases production of active Vitamin D
Term
Where are the adrenal glands found?
Definition
Close to the cranial poles of the kidneys
Term
What tissue does the adrenal cortex arise from?
Definition
Glandular Tissue
Term
What tissue does the adrenal medulla arise from?
Definition
Neural Tissue
Term
What does the adrenal cortex respond to?
Definition
Increased ACTH
Term
What types of hormone does the Adrenal Cortex produce?
Definition
Steroid Hormones
Term
What are the three types of Steroid Hormone?
Definition
Glucocorticoids
Mineralocorticoids
Sex Hormones
Term
What are the three examples of Glucocorticoids?
Definition
Cortisone
Cortisol
Corticosterone
Term
What are the functions of Glucocorticoids?
Definition
To increase Gluconeogenesis
To increase Blood Glucose Levels
Term
When are Glucocorticoids released?
Definition
In response to stress
Term
Give an example of a Mineralocorticoid
Definition
Aldosterone
Term
What are the functions of Aldosterone?
Definition
Regulate Sodium and Potassium Levels
Increases reabsorption of Sodium in the Kidneys
Increases Potassium excretion
Raised Blood Pressure
Term
Name the adrenal sex hormone released in males?
Definition
Androgens
Term
Name the adrenal sex hormone released in females?
Definition
Oestrogens
Term
Both Androgen's and Oestrogen are produced in both males and females, true or false?
Definition
True
Term
What two hormones are produced in the adrenal medulla?
Definition
Adrenaline
Noradrenaline
Term
What controls the release of adrenaline and noradrenaline?
Definition
The sympathetic innervation which is part of the autonomic nervous system
Term
What type of neurotransmitter is noradrenaline and adrenaline?
Definition
Excitatory Neurotransmitters
Term
What are the hormone producing cells in the pancreas found in?
Definition
Islets of Langerhans
Term
What are the three types of cells found in the pancreas?
Definition
Alpha Cells
Beta Cells
Delta Cells
Term
What do the Alpha Cells produce?
Definition
Glucagon
Term
What do the Beta Cells produce?
Definition
Insulin
Term
What do the Delta Cells produce?
Definition
Somatostatin
Term
What is the function of Insulin
Definition
To decrease high levels of blood glucose in the blood encouraging it to be stored as glycogen
Term
What is the function of Glucagon?
Definition
To increase low levels of blood glucose by stimulating glucongeogenesis and mobilising glycogen stores
Term
What is the function of Somatostatin?
Definition
To control the release of insulin and glucagon
Term
Where are the reproductive hormones produced?
Definition
In the testes and ovaries
Term
What hormone does the kidneys produce?
Definition
Erythropoietin
Term
What hormone does the stomach produce?
Definition
Gastrin
Term
What hormone does the small intestine produce?
Definition
Secretin
Cholecystokinin
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