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What internal organ has the greatest power of regeneration in the body? |
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Cells of the liver that all look alike and DO NOT specialize. |
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The liver produces about how many different chemicals? |
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Where in the body is the liver located? |
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Definition
Anchored to the underside of the diaphragm |
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Anterior surface, found at midline of the body, used to divide the liver into small left lobe and large right lobe |
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Double layer of parietal peritoneum - "anchors" liver to ventral abdominal wall |
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Superior surface; surrounds the bare area (no area peritoneum on the bare area) |
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Anchors liver to the diaphragm |
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Round ligament - posterior surface; same plane as the falciform ligament |
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Imbedded on the back of right lobe of liver |
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Liver uses blood while it is in the _____ _____. |
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Once blood reaches the _____ _____, the liver is dont with the blood. |
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________ _______ flows in the opposite direction of blood. |
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Right and Left hepatic ducts combine to form the ____ ____ ____. |
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Common hepatic duct combines with the cystic duct from the gallbladder to form the _____ _____ _____. |
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Common bile duct connects with the _____ _____ of the pancreas. |
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Definition
hepatic portal vein, hepatic artery, bile duct |
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Initially voluntary; then it becomes entirely reflexive |
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Definition
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During swallowing when the larynx elevates, the epiglottis... |
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Definition
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Definition
Movement of food down the esophagus |
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Definition
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Has millions of gastric glands; secreting gastric juice |
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Definition
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Gastric glands have what 3 types of cells |
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Definition
mucous cells (goblet), parietal cells, and chief cells |
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Thick, sticky, lines stomach walls |
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Definition
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secrete ezymes, primarily pepsinogen (inactive) |
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Hows does pepsiongen become active? |
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Definition
With combination of HCl it becomes pepsin |
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- a protease (protein digestor) - attacks ant protein; not picky; but does not fully digest - long polpeptides - pepsin - short polpeptides - fully formed pepsin would kill chief cells if made in this form, that is why the secrete pepsinogen |
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- provides optimum pH for pepsin to operate - helps activate pepsinogen - breaks tertiary & quarternary protein bonds - kills many bacteria |
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What are the 3 phases of gastric secretion? |
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Definition
- cephalic phase - gastric phase - intestinal phase |
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Conditioned reflex via vagal stimulus to the stomach; occures prior to food entering the stomach or mouth; just thinking about food or smelling food you like |
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Definition
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endocrine response; occurs when food arrives in the stomach; gastrin hormone is released (does not go into the stomach) - target: gastric glands |
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Occurs after the stomach is empty if chyme is still present in duodenum or proximal jejunum |
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Definition
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How long does food remain in the stomach? |
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Definition
pure carb - w/in 2 hours high fat or protein - w/in 6 hours |
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What causes inhibition of gastric secretion? |
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Definition
- unappetizing food (cephalic phase only) - sympathetic stimulus - acid build up in stomach (neg-feedback mech.) - fatty & or chyme in proximal small intestine |
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Term
Fatty & or chyme build up in the proximal small intestine stimulates what other 2 digestive hormones? |
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Definition
- secretin - CCK (cholesystokinin) |
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Term
What does the hormone secretin target? |
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Definition
Neck cells in the pancreas (acini) |
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What does the hormone CCK target? |
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Definition
Acinar cells in the pancreas |
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Where does almost all of digestion and absorption occur? |
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Definition
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For digestion and absorption to occur in the small intestine we need secretions from where? |
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Definition
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Aqueous juice; sodium bicarbonate; no enzymes; used to neutralize acid from the stomach; targeted by secretin |
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Definition
Neck cells in the pancreas (acini) |
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enzyme juice; works virtually on any type of food molecule you have coming in; targeted by CCK |
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Definition
acinar cells in the pancreas (acini) |
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Name 5 pancreatic enzymes |
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Definition
- amylase - cholesterol esterase - lipase - nucleases - proteases |
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What pancreatic enzyme breaks down starches to dissacharides? |
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Definition
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Which pancreatic enzyme breaks large cholesterol clumps in to individual cholesterols? |
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Definition
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Which pancreatic enzyme breaks down triglycerides - monoglycerides - glycerol - FFAs |
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Definition
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Term
What makes up a triglyceride? |
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Definition
glycerol (3 carbons) + 3 fatty acids |
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Which pancreatic enzyme breaks down DNase and RNase? |
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Definition
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The pancreatic enzyme protease has 3 diff types, what are they? |
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Definition
- tripsinogen - chymotrypsinogen - procarbocypeptidase |
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Term
_____ synthesizes bile & the _______ stores and concentrates bile. |
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Definition
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Thick, yellowish. alkaline pH, contains water, cholesterol, and inorganic salts |
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Definition
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Definition
- biliverdin (greenish/yellowish in color) - bilirubin (redish/brownish in color), gives feces its color - result of hemoglobin breakdown |
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emulsify fats - taking big fat droplets and breaking them into tiny soluble fat droplets |
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One end that is polar, hydrophilic; the other end is non-polar, hydrophobic, loves fat |
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Formed around tiny fat droplets (spherical) with polar heads facing out and nonpolar tails facing the fat |
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Definition
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Liver bile synthesized because: |
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Definition
-secretion -vagal stimulation |
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Gallbladder released because: |
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Definition
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Targets:neck cells of pancreas, liver to produce bile Inhibits:gastric secretion and motility |
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Definition
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Targets:acinar cells (release of enzyme juice), gallbladder to release bile Inhibits:gastric secretion and motility |
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Definition
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Definition
Secrets mucus, amylase (small amount), enterokinase (activates trypsiogen) |
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Definition
Membrane bound enzymes of microvilli |
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Definition
Membrane bound enzymes of microvilli |
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Breaks bond between table sugar, glucose-frutose (sucrose) |
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Definition
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Act as active transport "pumps" - completely absorbed carbs |
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Breaks bond between glucose-glucose (maltose) |
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Definition
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Breaks bond between lactose |
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Definition
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Breaks down peptides by breaking down 2 amino acids and the actively transport them into the cell |
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Definition
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Term
How do triglycerides enter a cell? |
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Definition
The have to be broken down, then put back together (not necessarily in the same way) |
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Term
Triglycerides collect into tiny droplets that become encased in proteins forming a type of lipoprotein called ________. |
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Definition
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Too big to pump into blood capillary, but they do diffuse into lacteals (lymoh capillaries) which are much more permeable than blood capillaries |
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Definition
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What color is lymph when it is actively absorbing fats? |
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Definition
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What happens to the water in chyme as it moves through the ileocecal valve into the large intestine? |
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Definition
Must be moved out, sodium and chloride leave the intestines with water following |
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Breaks down glycogen forming glucose; raises blood sugar |
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Definition
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Makes glycogen from glucose; lowers blood sugar |
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Definition
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What are the 2 condition in which our bodies can produce alot of ketones? |
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Definition
-starvation -uncontrolled diabetes -extreme low carb diets |
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Term
Ketones are formed from excess _____ |
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Definition
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Ketones are made because the cells are starving for _______. |
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