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The Circulatory System
blood, circulation, heart, veins, arteries
108
Physiology
Undergraduate 2
09/27/2011

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Cards

Term
Where is the heart located?
Definition
In the region of the thoracic cavity called the mediastinum.
Term
What is the endocardium?
Definition
the innermost layer of the heart wall providing a smooth surface to reduce friction between blood and the wall of the heart.
Term
What type of epithelium does the endocardium consist of?
Definition
a layer of simple squamous also called the endothelium 
Term
What is the myocardium?
Definition
the middle layer of the heart wall can consists of cardiac muscle
Term
What are the two motor units of the myocardium?
Definition

1) one forming the walls of the top two chambers of the heart

 

2) one forming the walls of the bottom two chambers of the heart

Term
Which side of the myocardium is the thickest? Why?
Definition
the left side is the thickest to provide the pwer needed to drive blood through the aorta and through the body
Term
Where does the right ventricle pump blood to?
Definition
to the lungs
Term
What is the epicardium?
Definition
the outermost layer of the heart
Term
This internal structure separates the 2 top & 2 bottom chambers and provides support for the heart valves.
Definition
annulus fibrosus
Term
What is the pericardium?
Definition
a triple layed bag that protects and anchors the heart
Term
Which pericardium makes up the outer connective tissue layer that anchors the heart to the diaphragm?
Definition
fibrous pericardium
Term
What are the two layers of the serous pericardium and their functions?
Definition

parietal portion adheres to the fibrous pericardium

 

visceral portion is the epicardium

Term
What are the two top champbers of the heart called?
Definition
atria
Term
What separates the two top chambers and prevents blood from flowing from one atrium to the other?
Definition
interatrial septum
Term
What are the two bottom chambers?
Definition
ventricles
Term
What seperates the two bottom chambers that prevents blood from entering from one ventricle to another
Definition
interventricular septum
Term
What seperates the atria from the ventricles?
Definition
atrioventricular septum
Term
This valve consists of three thin flaps of tissue that create a one-way passage between the right atri and the right ventricle.
Definition
tricuspid valve
Term
What is the name of the cardiac muscle that the edges of the tricuspid flaps are attatched to?
Definition
papillary muscles
Term
What happen each time the myocardium of the ventricles contracts?
Definition
the chordae keep the valve from opening into the right atrium
Term
What are the cords of collagenous fiberts that attach the papillary muscles to the edges of the tricuspid valve?
Definition
chordae tendinae
Term
Which valve seperates the chambers on the left side of the heart and only has two flaps?
Definition
bicuspid or mitral valve
Term
What are the valves that consist of three adjacent cups and prevent blood from flowing back into the heart?
Definition
semilunar valves
Term
This valve is found in the opening of the aorta and prevent blood from flowing from aorta back into the left ventricle.
Definition
aortic semilunar valve
Term
This valve is found in the opening of the pulmonary trunk and prevents blood from reentering the right ventricle.
Definition
pulmonary semilunar valve
Term
What is the surface depression called taht delineates the boarder between the left atrium and the left ventricle?
Definition
left atrioventricular sulcus
Term
Where is the great cardiac vein and circumflex artery found?
Definition
In the left atrioventricular sulcus
Term
What is the surface depression that delineates the right atria from the right ventricle and contain the right coronary artery?
Definition
right atrioventricular sulcus
Term
A surgeon is looking for the great cardiac vein and the anteriour interventriuclar artery located over the interventriular septum, between the left and right ventricles. What would this space be called?
Definition
The anterior interventriuclar sulcus
Term
Veins flow __________
Definition
towards heart
Term
Arteries flow _____________
Definition
away from heart
Term
Where is the posterior interventricular sulcus located? What is also located here?
Definition
it is located over the interventriular septum on the back of the heart which contains the middle vein and posterior interventricular artery.
Term
What are the veins that deliver blood to the right atrium?
Definition
vena cavas
Term
which vena cava delivers blood, low in oxygen from the upper body?
Definition
superior vena cava
Term
which vena cava delivers blood from the lower body?
Definition
inferior vena cava
Term
What is the name of the stucture that carries blood from the right ventricle to the pulmonary arteries?
Definition
pulmonary trunk
Term
This structure splits in right & left directions and delivers blood to the lungs
Definition
pulmonary arteries
Term
These veins deliver blood to the left atrium
Definition
pulmonary veins
Term
What carries the blood from the left ventricle through the thoracic and abdominal cavities?
Definition
aorta
Term
What is the term used to describe the circulation of blood through the heart?
Definition
cardiac cycle
Term
The right atrium receives blood from the superior and inferior vena cavas as well as from the  _______ _______ and several small veins.
Definition
coronary sinus
Term
Which veins deliver blood to the left atrium and how many are there?
Definition
pulmonary; 4
Term
What opens the cuspid valves as blood enters the atria?
Definition
blood flowing from high pressure to low pressure
Term
What makes blood pressure increase in the ventricle?
Definition
when the ventricle wall begins to contract in causes the blood pressure to increase (systole)
Term
The cuspid valves close when blood pressure in the ventricles is ______ than in the atria.
Definition
higher
Term
The ________ ________ open and blood leaves the ventricles when blood pressure in ventricles is higher than in the pulmonary trunk or aorta.
Definition
semilunar valves
Term
When blood pressure in the pulmonary trunk is _____ than in the ventricles, the semilunar valves close.
Definition
higher
Term
At the end of ventriclar contraction the myocardium ______ and blood pressure falls in the expanded, somewhat empty ventricles allowing the cuspid valves to reopen and the cycle to begin again.
Definition
relaxes
Term
What is the first sound that represents the cuspid valves closing at the beginning of the ventricular contraction?
Definition
"lub"
Term
What is the second sound representing the closing of the semilunar valves?
Definition
"dub"
Term
The flow of blood through the coronary vessels is the result of the interaction between ________ and  _________.
Definition
aortic blood prssure and intramural pressure
Term
What is the driving force for the flow of blood through the coronary vessels? inhibitory force?
Definition

driving force is aortic blood pressure

inhibitory is intramural pressure

Term
What determines the force by which blood enters the coronary blood vessels and travels to the mycardium?
Definition

driving force is aortic blood pressure

i

Term
A compression of the coronary vessels by contraction of the myocardium can close the coronary vessels and stop the flow of blood can be caused by?
Definition
Intramural pressure the inhibitory force
Term

When aortic blood pressure is greater than aortic blood pressure, blood _______

 

ABP>IP

Definition
 flows
Term

When intramural pressure is greater than aortic blood pressure, the blood _______

 

IP>ABP

Definition

slows or stops

 

 

Term
Coronary vessels dilate in response to high levels of ________, increaseing blood flow to the myocardium.
Definition
CO2
Term
Where do cardiac impulses originate?
Definition
in the SA node, located at the point where the superior vena cava enters the right atrium
Term
What is the SA node composed of?
Definition
it is composed of autorhythmic cells that continuosuly depolarize
Term
The resting membrane potential is unstable due to a reduced outflow of ___________ relative to the __________ entering the cells through passive channels.
Definition
potassium ions; sodium ions
Term
The interior of the cell becomes more positive until threshold of _____ is reached.
Definition
-40mV
Term
What happens at -40mV threshold?
Definition
voltage gated fast calcium ion channels open, calcium rushes into the cells and an action potential is generated.
Term
Why is the SA node concidered the pacemaker for the heart?
Definition
because it depolarizes more frequently than any other heart region @ 100 times/minute
Term
Where is the AV node located?
Definition
immediately above the tricuspid valve in the interatrial septum
Term
How are the cells of the AV node activated?
Definition
by implulses spreading from the SA node via the intercalatated disks (gap junctions) of atrial cardiac muscle cells
Term
While the AV node actas as a gatekeeper, how many impulses are let through at a time?
Definition
one in a fraction of a second
Term
Where does the AV node send impulses to?
Definition
to the ventricles via the bundle of His
Term
What is the bundle of His?
Definition
a specialized strand of cardiac muscle that is continuous with the AV node and enters the upper end of the interventriuclar septum
Term
Can the AV node act as a pacemaker if the SA node is destroyed?
Definition
yes, but at a much slower pace
Term
After the bundle of His splits and gives rise to conduction bundles where does it travel?
Definition
they travel down to the interventricular septum and stimulate cells of the septum
Term
What system is the bundle of His apart of?
Definition
purkinje system
Term
Where do the left and right branches supply impulses too?
Definition
first to the papillary muscles and then to the myocardium of each ventricle
Term
Where are pukinje fibers found and what are they responsible for?
Definition
on the inner surface of the heart beneath the endocardium and are responsible for the nearly simultaneous contraction of the two ventricles
Term

Note* the spread of impulses through the myocardium of either ventricle is from contractile cell to contractile cell

 

Definition
Term

Na+ and CA++ diffuse through the ____________ and inititiate depolarization

Definition
intercalated disks
Term
At at threshold of about _____mV, voltage gated NA+ channels open
Definition
-80
Term
What happens after voltage gated NA + channels open
Definition
Na+ enters the cell, completeing depolarization at +25
Term
What happens at +25?
Definition
voltage gated Ca++ channels open, providing the calcium that will bind with troponin and initiate contraction and voltage gated K+channels open for repolarization
Term
Where is the cardioinhibitory and cardioacceleratory reflex centers found?
Definition
in the medulla oblongata
Term
The _______ nerve slows the heartbeat rate via the release of acetylcholine
Definition
vagus
Term
What happens when acetylcholine binds to muscarinic receptors?
Definition
causes potassium ion channels to open
Term
An outflow of potassium _________ the heart cellls and _______ the heart.
Definition
hyperpolarizes ; inhibits
Term
Which nerve increases the heartbeat via the release of norepinephrine?
Definition
the cardiac nerve
Term
What does the norepinephrine bind to, causing the Ca++ ion channels to open?
Definition
beta receptors
Term
The inflow of Ca++ ________ the cell and ultimately ________ contraction.
Definition
depolarizes; initiates 
Term
What is it called wen both teh sympathetic and parasympathetic divisions of the autonomic nervous system, send impulses but the parasympathetic dominates?
Definition
vagal tone
Term
The division of the circulatory system where osmotic pressure is greater than osmotic pressure is?
Definition
capillary
Term
What is the endothelial tunica of a blood vessel?
Definition
tunica intima
Term
What is the pattern of ciculation that includes the ductus arteriosus?
Definition
fetal circulation
Term
This is a change in an artery that occurs when the aortic or carotic sinus is stimulated.
Definition
vasodilation
Term
What is the muscular, elastic vessel that elps move and distribute blood?
Definition
Artery
Term
What is the tunica of a blood vessel wall that controls vasodilation and vasocontriction?
Definition
tunica media
Term
What is the resistance to blood flow, determined by the degree of vasodilation or constriction called?
Definition
peripheral resistance
Term
What is the pressure that results in filtration at the arterial end of a capillary?
Definition
Blood hydrostatic pressure
Term
What is the vessel that carries blood toward the heart?
Definition
vein
Term
What is the vein in a fetus that carries oxygenated blood from the placenta to the baby?
Definition
umbilical vein
Term
What is the potential pressure of blood that dominates at the venous end of a capillary?
Definition
Osmotic pressure
Term
What is the strucures found in veins that keep blood from flowing backward?
Definition
Valves
Term
Capillaries that have pores in their walls are called?
Definition
discontinued
Term
The vessel where nutrients and wastes are exchanged with the tissues?
Definition
capillary
Term
The chemical that is a powerful vasoconstrictor and stimulates the release of aldosterone?
Definition
angiotensin
Term
The pattern of circulation supplied by the first branch off the aorta?
Definition
coronary circulation
Term
Autoregulatory stimuli that enhance blood delivery to a local area....
Definition

-reflect a given tissue's needs at the moment

-include chemicals that act as metabolic controls

-include falling O2 and rising CO2 levels in most tissues

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