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The Circulatory System
Basic ish Circulatory System Stuff
59
Biology
Undergraduate 2
02/08/2010

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Term
What are the 4 key points of the Animal Circulatory System?
Definition
1) Animal circulatory systems share basic elements.
2) Most invertebrates have open circulatory systems.
3) Some invertebrates and all vertebrates have closed circulatory systems.
4) Vertebrate circulatory systems have evolved from single to double blood circuits.
Term
What are the four basic components of the circulatory system?
Definition
1) Circulating fluid (Blood or hemolymph.)
2) Pump to provide pressure (Tubular and Chambered hearts).
3) Blood vessels or channels (for transport over distance).
4) Area for exchange of gases (O2 and Co2, Nutrients and waste): Capillaries or Sinuses.
Term
How do simple invertebrates (sponges, cnidarians, flatworms) operate?
Definition
They use cilia and flagella. Pick up O2 and nutrients, release waste and CO2.
Term
Why can substances not by exchanged with the environment by diffusion in larger animals?
Definition
They have more complex systems -- organs are deep in the body.
Term
What and where is an Open Circulatory System?
Definition
It is in most invertebrates and the heart pumps hemolymph into vessels that empty into body spaces (sinuses) before returning to the heart.
Term
What and where are Closed Circulatory Systems?
Definition
They are in some invertebrates and all vertebrates. Blood is confined in blood vessels throughout the body (does not mix with interstitial fluid.)
Term
What are the advantages to the Invertebrate Open Circulatory System?
Definition
1) Less resistance
2) Less efficient pump needed.
3) Less energy required.
Term
What are some advantages offered by closed circulatory systems?
Definition
1) Blood is maintained at a higher pressure and moves more rapidly through the body.
2) Allows precise control of distribution and rate of blood flow via muscles that contract or relax to adjust the diameter of the vessels.
Term
Summarize the evolution of the vertebrate circulatory system.
Definition
It evolved from a heart with a single series of chambers (single circuit) to a double heart the pumps blood through separate pulmonary and systemic circuits.
Term
Summarize the amphibian circulatory system.
Definition
It is a double blood circuit -- Pulmocutaneous and Systemic. The heart is divided into three chambers -a right atrium, a left atrium, and the Ventricle.Oxygenated blood from the lungs and skin and deoxygenated blood from the rest of the body are kept partially separate by a smooth pattern of a flow and a flap of tissue in the large artery leaving the heart.
Term
Summarize the circulatory system of turtles, lizards, and snakes
Definition
This is almost identical to the amphibian, except that now a wall of tissue called the septum completely separates the oxygenated blood from the deoxygenated blood.
Term
Summarize the circulatory system of crocodiles, birds, and mammals.
Definition
Now a complete septum forms two ventricles and creates a four chambered heart which keeps oxygenated and deoxygenated blood completely separate.
Term
What are the four components of blood?
Definition
1) Plasma
2) Erythrocytes
3) Leukocytes
4) Plateles
Term
What is plasma?
Definition
An aqueous solution of proteins, ions, nutrient molecules and gases (91% water)
Term
What are erythrocytes?
Definition
The oxygen carriers of the blood.
Term
What are Leukocytes?
Definition
The body's front line of defense against disease.
Term
What are Platelets?
Definition
They induce blood clots that seal breaks in the circulatory system.
Term
What is Mammalian Blood?
Definition
A fluid connective tissue (usually 4-5 liters in humans) that consists of Blood Cells (Erythrocytes, leukocytes, and platelets) suspended in a fluid matrix (plasma).
Term
Where do human blood cells develop?
Definition
The red bone marrow of vertebrae, sternum, ribs, and pelvis.
Term
Blood cells arise from pluripotent stem cells that also give rise to what two types of cell?
Definition
1) Myeloid stem cells
2) Lymphoid stem cells.
Term
What are the three kinds of Plasma proteins?
Definition
1) Albumins
2) Globulins
3) Fibrinogen
Term
What are Albumin proteins involved with?
Definition
Osmotic balance, pH, transport hormones, waste, and drugs.
Term
What are globulins involved with?
Definition
Transport lipids (cholesterol), fat soluble vitamins, immunoglobins.
Term
What is Fibrinogen involved with?
Definition
Blood clotting
Term
What are the 5 plasma ions?
Definition
1) Na+
2) K+
3) Ca2+
4) Cl-
5) HCO3-
Term
List 4 important facts about Erythrocytes
Definition
1) They contain hemoglobin (transports O2 from lungs to body).
2) Mature erythrocytes have no nucleus or organelles.
3) They are flexible and can squeze through capillaries.
4) Their life span is 4 months.
Term
List 2 important facts about Leukocytes
Definition
1) They defend the body against infecting pathogens.
2) They eliminate dead and dying cells, debris.
Term
List two important facts about Platelets.
Definition
1) Cell fragments are enclosed in a plasma membrane.
2) They trigger clotting. They stick to collagen that is exposed whenblood vessels are damaged and release factors to bring more platelets to the region to seal off the damaged site.
Term
What are the five types of white blood cells in descending order?
Definition
NEVER (neutrophils)
LET (lymphocytes)
MONKEYS (macrophgaes/monocytes)
EAT (Eosinophils)
BANANAS (Basophils)
Term
What is EPO?
Definition
Erythropoietin, a hormone synthesized in the kidneys when O2 drops below normal. It stimulates bone marrow stem cells to produce more erythrocytes.
Term
What kind of valves are between the atria and ventricles?
Definition
The atrioventricular valves. (AV)
Term
What kind of valves are between the atria and ventricles?
Definition
The atrioventricular valves. (AV)
Term
What kind of valves are between the ventricles/aorta and pulmonary arteries?
Definition
Semilunar valves (SL)
Term
Which circuit is associated with the right heart?
Definition
Pulmonary
Term
Which circuit is associated with the left heart
Definition
Systemic
Term
What are some advantages of having separate systems?
Definition
1) Pressures can be different in the different systems.
2) Keeps high pressures from our lungs.
3) Allows high pressures in the body for sustained blood flow to maintain activity.
Term
Pulmonary arteries move blood...
Definition
From the heart to the lungs.
Term
Left pulomnary veins move blood
Definition
From the lungs to the heart.
Term
The superior vena cava moves blood
Definition
From the head and upper limbs to the heart.
Term
The inferior vena cava moves blood
Definition
From the trunk and legs to the heart.
Term
The aorta moves blood...
Definition
To the systemic circuit.
Term
Blood leaves the heart in.... which branch into smaller...
Definition
arteries; arterioles.
Term
_____ deliver blood to capillary networks.
Definition
Arterioles.
Term
_____ exchange substances between blood and interstitial fluid.
Definition
Capillaries.
Term
Small _____ collect blood from capillaries.
Definition
Venules.
Term
Venules join into larger ____ that return blood to the heart.
Definition
Veins
Term
F=
Definition
DeltaP/R
Term
Delta P =
Definition
The change in pressure from one end of the tube to the other.
Term
R=
Definition
8Ln/pi r.
L= Length of the tube
n = fluid viscosity
r = inside radius of the tube.
Term
What is the cardiac cycle?
Definition
The systole-diastole sequence.
Term
What is the systole?
Definition
The ventricle contracting.
Term
What is the Diastole?
Definition
The ventricle relaxing, the chambers filling, and the atria contracting.
Term
Blood moves as a result of what?
Definition
Pressure Differences.
Term
What is the cardiac cycle triggered by?
Definition
Action potentials that spread across the cardiac muscle cell membranes.
Term
What is Systolic pressure?
Definition
The contraction of ventricles pushing blood into arteries at peak pressure.
Term
What is diastolic pressure?
Definition
Between contractions when blood pressure in arteries falls to a minimum pressure.
Term
What are the five steps of the Cardiac cycle?
Definition
1) The heart is fully relaxed and the atria begins to fill with blood. AV and SL valves are closed.
2) Blood fills the atria and pushes AV valves open, the ventricles begin to fill.
3) The atria contract, filling the ventricles completely.
4) The ventricles begin to contract, forcing the AV valves closed. The SL valves remain closed.
5) The ventricles contract fully, forcing SL valves open and ejecting blood into arteries.
Term
Cardiac Output (CO) =
Definition
Stroke Volume (SV) x Heart Rate (HR).
Term
What are the two things that effect cardiac output?
Definition
1) The amount of blood going out per beat.
2) The number of beats per minute.
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