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The Chromosomal Basis of Inheritance
Chapter 15 Campbell: Sex linked genetics
25
Biology
11th Grade
02/07/2011

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Term
wild type
Definition
phenotype most common in natural populations
Term
mutant phenotypes
Definition
alternative phenotypes to the wild type variety
Term
sex-linked genes
Definition
genes located on a sex chromosome (X or Y)
Term
linked genes
Definition
genes located on the same chromosome that tend to be inherited together
Term
genetic recombination
Definition
production of offspring with new combinations of traits inherited from two parents
Term
parental types
Definition
offspring phenotypes that match their parents phenotypes
Term
recombinants
Definition
offspring with phenotypes different than parental phenotypes
Term
genetic map
Definition
ordered list of genetic loci along a particular chromosome
Term
linkage map
Definition
genetic map based on recombination frequencies
Term
cytological maps
Definition
location of genes along a chromosome based on stained band locations that can be seen with a microscope
Term
Duchenne muscular dystrophy
Definition
sex linked recessive disorder; rarely live past their 20's; progressive weakening of the muscles and loss of coordination
Term
hemophilia
Definition
sex linked recessive disorder; absence of a protein required for blood clotting
Term
Barr body
Definition
inactive X chromosome in each cell of a female; condenses into a compact object that lies along the inside of the nuclear envelope
Term
nondisjunction
Definition
members of homologous chromosomes that don't separate during anaphase
Term
aneuploidy
Definition
abnormal chromosome number
Term
trisomic
Definition
cell in which a chromosome is present in triplicate (2n+1)
Term
monosomic
Definition
missing chromosome (2n-1)
Term
polyploidy
Definition
more than two complete chromosome sets (triploidy 3n or tetraploidy 4n)
Term
duplication
Definition
extra copy of a gene or genes on a chromosome
Term
deletion
Definition
loss of a gene or genes on a chromosome
Term
inversion
Definition
reattachment of part of a chromosome in reverse order
Term
translocation
Definition
fragment of one chromosome breaks off and attaches to a nonhomologous chromosome
Term
Down syndrome
Definition
trisoply 21; disorder cause by aneuploidy where there is one more copy of chromosome 21
Term
genomic imprinting
Definition
paternal or maternal effects put on genes based on whether they came from the mom or dad
Term
fragile X syndrome
Definition
(genomic imprinting) mom passes on abnormal X chromosome causing mental retardation
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