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Tetracylines
Tetracylines
10
Pharmacology
Professional
08/19/2012

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Term
MOA of Tetracylines.
Definition

inhibits bacterial protein synthesis by reversible binding to 30s ribosomal subunit.

Term
Name the tetracyclines.
Definition

Doxycycline (Vibramycin, Doryx)

Minocycline (Minocine)

Tetracyline (Sumycin)

Term
Describe antibiotic activity of tetracyclines.
Definition

Activity agianst atypicals, spirochetes, Rickettsial diseases, anthrax, syphilis, acne &c.

Term
Name a unique side effect of tetracylines.
Definition
Tooth discoloration (in children)
Term
Administration of tetracyclines.
Definition

Take with 8 oz water to minimize GI irritation. Remain upright for 30 minutes.

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Term
Which of the tetracyclines shouldn't be dose adjusted in renal imparitment.
Definition
Doxcycline
Term
Tetracycline absorption is impaired by what?
Definition

Antacids. Seperate dose by 1-2 hours before or 4 hours after.

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Term
What will tetracylines do warfarin.
Definition
Increase.
Term
Tetracyclines may decrease effectiveness of oral contraceptives (check package insert)
Definition
Statement. Not a question.
Term
Many anticonvulsants decrease levels of tetracyclines.
Definition
Statment. Not a question.
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