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Definition
-body makes antibodies (immunoglobulins) in response to bacteria or virus |
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-exposure to antigen or by passive injection of immunoglobulins (vaccine) |
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Definition
-geneticall determined in specific populations |
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Term
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Definition
-administering small amount of antigen
-stiumlate immune response
-does not give disease
-inactivated, attenuated, toxoid, conjugate, recombinant subunit |
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Definition
-whole or part of killed microorganism |
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-live, weakened microorganism |
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-inactivated toxins, disease-producing substance produced by microorganism |
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Term
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Definition
protein or toxoid from unrelated microorganism that links to the outer coat of disease-causing microorganism, creating a substance that is recognized by immature immune system (infants-Haemophilus influenza B) |
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Term
Recombinant subunit vaccine |
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Definition
-insert some of the genetic material (DNA) of a pathogen into another cell/organism, producing antigens; antigens then used as vaccine in place of the whole pathogen (Hepatitis B) |
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Term
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Definition
-person receives antibodies against a particular pathogen from another source (newborn infant recieves maternal antibodies via placenta), (administration of antibodies)
-short-lived (weeks-months, then no longer present)
-no immune response experienced
-used if own immune response incapable of producing effective immune response
-exposed person at high risk of complications from exposure
-used when time does not permit active vaccination |
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Definition
-check prescription, OTC use
-food & drug allergies |
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Foreign travel immunizations |
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Definition
-typhoid
-yellow fever
-specific to travel area |
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Term
Reporting Adverse Reactions to Vaccines |
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Definition
-chart lot# when vaccination given
-adverse reaction reported to VEARS (Vaccine Event Adverse Reporting System) |
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Term
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Definition
-vaccine for chicken pox
-may provide prophylaxis w/ exposure or 3-5 days
-dose: 0.5 ml SQ, 2 doses (1st @ 12-15 months, 2nd @ 4-6 yr)
SE: injection site reaction, fever, chickenpox-like rash (mild)
-Adverse: encephalitis, Steven-Johnson syndrome, thrombocytopenia, anaphylaxis
CI: immune-compromised, pregnancy or possibility of, active/untreated TB, moderate-severe illness
-drug-drug: No salicylates for 6 wk (Reye syndrome), no high dose steroids, no vaccine for 5 months if transfusion or immune globulins |
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