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Test #4 Chapters 28-40
Antivirals, antimalarials, & antihelmintics
22
Pharmacology
Undergraduate 2
03/27/2011

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Cards

Term
Viral infections
Definition

-influenza A, B, C

-Herpes 1 (oral, cold sores)

-Herpes 2 (genital)

-Herpes 3 (chicken pox & shingles)

-Herpes 4 (Epstein-Barr, mono)

-Herpes 5 (CMV, cytomegalovirus)

-Hepatitis A, B, C, D, E, etc. -H

Term
Amantadine (Symmetrel)
Definition
-non-HIV antiviral for influenza A
Term
Rimantadine (Flumadine)
Definition
-non-HIV antiviral for influenza A
Term
Vidarabine (Vira-A)
Definition
-non-HIV antiviral for h. zoster, v. zoster, HSV-1
Term
Entecavir (Barraclude)
Definition
-non-HIV antiviral for chronic Hep B
Term
Adefovir (Hepsera)
Definition
-non-HIV antiviral for chronic Hep B
Term
Zanamivir (Relenza)
Definition
-non-HIV antiviral; take w/ in 48 hrs of flu
Term
Oseltamivir (Tamiflu)
Definition
-non-HIV antiviral; take w/ in 48 hrs of flu
Term
*Acyclovir (Zovirax)
Definition

-non-HIV antiviral for HSV-1 & 2

-dose: 200-400 mg po, HSV-1; 800 mg po, h. zoster

-SE: n/v/d, headache, tremors, rash, phlebitis

-Adverse: seizures, nephrotoxic, bone marrow depression, neuropathy

Term
Didanosine (Videx)
Definition
HIV antiviral
Term
Lamivudine (Epivir)
Definition
-HIV antiviral
Term
Nevirapine (Viramune)
Definition
HIV antiviral
Term
Stavudine (Zerit)
Definition
HIV antiviral
Term
Nelfinavir (Viracept)
Definition
HIV antiviral
Term
Ritonavir (Norvir)
Definition
HIV antiviral
Term
Saquinavir (Invirase)
Definition
HIV antiviral
Term
Antimalarials
Definition

-malaria incubation 10-35 days w/ flu-like symptoms

-acute tx: chloroquine, mefloquine

-prophylaxis (prevention): chloroquine, primaquine

Term
*Chloroquine (Aralen)
Definition

-prophylaxis & acute malaria tx

-dose: 600 mg, then 300 mg po acute; 5 mg/kg/wk for 2 wk before & 6-8 wk after exposure

-SE: n/v/d, fatigue, anorexia, blurry vision, nervousness, pruritis

-Adverse: psychosis, hypotension, EKD changes, aplastic anemia, ototoxicity, CV collapse

-drug-drug: increased effects of digoxin & warfarin

Term
Antihelmintics
Definition

-treat parasitic worm infestation- tapeworm, roundworm, fluke, tissue roundworms

-get from contaminated food

-SE: GI distress, dizziness, headache, drowsiness

-usually given for 1-3 days

Term
Mebendazole (Vermox)
Definition
-antihelmintic for pinworms, roundworms, hookworms
Term
Pyrantel pamoate (Antiminth)
Definition
-antihelmintic for pinworms, roundworms, hookworms
Term
Antiviral, Antimalarial, & Antihelmintic Nursing Measures
Definition

-hand hygiene

-wash clothing, bedding

-follow-up stool specimen needed

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