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venous blood is more acidic/alkyline that arteriole blood |
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what decreases excitability of muscles/nerves? |
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Definition
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what increases excitability of muscles/nerves? |
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how does acidosis affect kidney function (reabsorption/secretion) |
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Definition
kidney substitutes secretion of K+ for H+, so K+ is retained in cell and hyperkalemia results |
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major source of H+ in body? |
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Definition
carbonic acid production from CO2 and H20 |
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3 places of defense against pH changes |
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Definition
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Henderson Hasselbach equation? |
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Definition
ph = pka + log (unprotonated)/(protonated) |
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high levels of H+ does what to ventilation? |
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Definition
increases to decrease CO2 levels |
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low levels of H+ does what to ventilation? |
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Definition
lowers it (depresses) to increase amounts of CO2 and therefore H+ |
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if PCO2 rises, what does kidney do? |
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Definition
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what is the cause of acidosis/alkalosis if CO2 levels are off? |
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Definition
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what is the cause of acidosis/alkalosis if HCO3- is abnormal |
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Definition
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cause of respiratory acidosis? |
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Definition
retnention of CO2--hypoventilation |
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how do u compensate for respiratory acidosis? |
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Definition
retain HCO3- to balance out the elevated CO2 |
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causes of metabolic acidosis |
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Definition
diarrhea (loss of HCO3-) diabetes, xs fat metab, ketoacidosis, exercise (lactic acid), uremic acidosis-renal failure |
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how do u compensate for metab acidosis? |
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Definition
increase pulmonary function, hyperventilate, excrete acid, connserve more HCO3- |
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causes of respiratory alkalosis: |
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Definition
loss of CO2 (hyperventilation) fever anxiety aspirin poisoning, high alts |
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how do u compensate for resp alk? |
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Definition
conserve H+ and excrete HCO3- |
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Term
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Definition
vomiting ingestion of alk drugs |
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Term
compensation for metab alk? |
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Definition
hypoventilation (conserve CO2) secrete less H+ and excrete more HCO3- |
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